Asfarviridae

Question 1

Morphology

Answer 1

linear dsDNA
icoshederal capsid

enveloped

Question 2

Resistance

Answer 2

weak

but can survive for months in raw meat

Question 3

Biological properties

Answer 3

Baltimore I - multiplicates in the cytoplasm of lymphoid cells - buffy coat culture

stenoxen
hemabsorption
transmission: contact, arbo (ticks)
reservoir (africa) : wart-hog

Question 4

Genus

Answer 4

Asfivirus

Question 5

antigenetic properties

Answer 5

hidden protective antigen - no neutralizing antibodies.

immunocomplex deposition - clinical signs.

Question 6

Diagnosis

Answer 6

PCR
clinical signs are similar to classical swine fever

isolation - buffy coat

IF
ELISA
hemabsorption.

Question 7

Asfivirus

Answer 7

African swine fever

swine - high mortality and morbidity
acute fever, hemorrhage (skin, organs)
chronic: paralysis, weaning

Death follows quickly with high viral infection

Question 8

Is there vaccines?

Answer 8

No

Question 9

Is it a persisting infection?

Answer 9

Yes, Immunoglobulins are not effective.