Adenoviridae

Question 1

Morphology

Answer 1

linear dsDNA
icsohederal capsid + fibers (HA activity)
non enveloped

Question 2

Resistance

Answer 2

strong.

Question 3

Biological properties

Answer 3

Baltimore I. – cellular transcriptase
stenoxen (except BAV II subtype, CAV-1)
CPE: nuclear inclusion bodies, rounding, lysis
oncogenity – apoptosis inhibition

Question 4

Antigenic properties

Answer 4

good antigens

cross reaction - AGP, CF, ID - 2/3 subgroups

Serotyping: VN, HAI

Question 5

Genus

Answer 5

Mastadeno-
Aviadeno-
Atadeno-
Siadeno-
Ichtadenovirus

Question 6

Mastadenovirus genus:

Answer 6

(mastos – breast)
Pneumoenteritis of calves (BAV 1-3, 9)

Pneumoenteritis of lambs (OAV 1-6), bladder stone

Infectious canine hepatitis – Fox encephalitis (CAV-1)

Canine laryngotracheitis (CAV-2) – kennel cough

Human adenoviruses (HAV 1-41) – military disease

Question 7

Diagnosis

Answer 7

isolation
AGID, VN
PCR

Question 8

Aviadenovirus genus: (avis – bird)

Answer 8

Chicken (12), turkey (2), goose (3), pigeon adenoviruses Inclusion body hepatitis,
nephritis, gizzard erosion
CELO, GAL

Question 9

Atadenovirus genus:

Answer 9

(high A and T content of the genome)
Pneumoenteritis of calves (BAV 4-8, 10) and lambs

Egg drop syndrome (EDS)

Snake adenoviruses

Question 10

Siadenovirus genus: (sialidase enzyme gene)

Answer 10

• Hemorrhagic enteritis of turkey / Marble spleen disease of pheasant
• Frog adenoviruses

Question 11

Ichtadenovirus genus: (fish adenoviruses)

Answer 11

•Sturgeon adenovirus