Pancreas and muscle shennanigans Flashcards
What are two major problems with the exocrine pancreas?
Inflammation (Pancreatitis)
Exocrine pancreatic insufficiency
What are some risk factors for pancreatitis in dogs?
Obesity, high fat diet, endocirne disease
T/F Serum amylase and/or lipase are really good at detecting pancreatitis
NO; They suck
You suspect a dog has pancreatitis; what test do you run?
PL; PLI (Pancreatic lipase immunoreactivity)
You suspect a dog has exocrine pancreatic insufficiency. What test do you run?
TLI
What are some causes of EPI?
Pancreatic acinar atrophy
Chronic pancreatitis
Pancreatic duct obstruction
T/F EPI is relatively uncommon in cat
TRUE
What is malassimilation?
Inability of the GI tract to take up ingested nutrients secondary to maldigestion or malabsorption
You suspect an animal is suffering from malassimilation. What tests would you run/
Serum cobalamin
Serum folate
If you see decreased serum folate, what part of the SI do you suspect disease?
Proximal
If you see a decreased serum cobalamin what part of the SI do you expect has disease?
Distal
T/F Muscle is the major tissue in most animals
URRR DURRRR
What is the most specific and sensitive indicator of muscle damage?
Creatine kinase
T/F You can get a false positive CK test with hemolysis
TRUE
What are some possible sources of AST?
Hepatocytes
Skeletal muscle
RBCs
