Liver Tests Flashcards
Test 1
Chug a beer
10 pushups
chug a second beer 15 jumping jacks
NO PUKING
You need _ % loss of fx to see liver changes?
70
2 general types of liver test?
direct
add on tests
indirect
part of routine chem panel
What are the two direct tests of liver fx?
Bile acids and Ammonia
How do you test for BA
Dogs/cats must fast for 12 hours, baseline, test 2 hours after eating
Horse/Rmt single measuremt
What are the 2 major pathologic processes that increase BA?
decreased clearance
loss of fx hepatocytes/recircualtion issue
shunt
decreased excretion of BA
cholestasis
when dont you run BA?
to test fx liver mass if cholestasis is suspected
When is ammonia tolerance test contraindicated?
if ammonia is already high
What causes hyperamonemia?
hepatic insufficiency
shunts- tolerance test indicated
urea cycle ez def- rare rare rae
RMT urea toxicosis
MAY SEE Ammonia biurate crystals
What is hepatic encephalopathy?
result of toxic levels of plasma ammonia
neuro signs
most severe after eating
What are the indirect liver tests?
glucose
outside ref interval
cholesterol
decreased
albuimin
decreased
BUN
decreased
Bilirubin
increased
What is hepatic photosensitivity?
phylloerythrin breakdown from chorophyll, removed by hepatocytes
enters circ, accumualtes in skin
+sun = free radicals leading to inflamm, unpig/hairless skin affected
T/F microcyotis/codocytes can result from decreased heaptic mass
TRUE
What indicates hepatic lipidosis
CATS
hyperbilirubinemia
increased ALP/GGT
+/- hyperammonemia
What indicates cholangitis, cholangiohepatitis, or extra hepatic biliary dz?
increased BA hyperbilirubinemia increased ALP/GGT increase in leakage ez hypercholesterolemia prolonged PT/PTT steatorrhea
