Monocytes/lymphocytes, Eosin/Baso

Question 1

Monocytes share the same lineage as what?

Answer 1

Neutrophils

Question 2

Monocytes have a similar mechanism to what?

Answer 2

Neutrophils

Question 3

Dogs and cats can see a monocyte increase in response to what?

Answer 3

Corticosteroid use

Question 4

What produces lymphocytes?

Answer 4

Bone marrow, lymph nodes, and other primary lymphoid tissues

Question 5

What are common causes of lymphocytosis?

Answer 5

Chronic inflammation: will also see neutrophilia, monocytosis with this
Physiologic: epinephrine induced due to increased blood flow
Lymphoproliferative disease: leukemic stage of lymphoma
Due to hypoadrenocorticism: lack of glucocorticoid hormones
Young animals: common in young animals

Question 6

If you see a leukocytosis, what is the one dz you should always consider?

Answer 6

Addison’s disease; will present with a leukocytosis and a neutropenia

Question 7

What are the causes of lymphopenia?

Answer 7

Acute inflammatory: increased margination into tissues
Corticosteroid use: most common cause. Shifts from circulating pool to other pools
Depletion: loss of lymph
Lymphoma associated: common; decreased production

Question 8

Eosinophils are short/long lived in the blood

Answer 8

Short lived

Question 9

Eosinophilia can be due to what?

Answer 9

Allergic/hypersensitivity disorders 
Parasitism 
Other inflammatory processes
Mast cell degranulation 
Hypoadrenocorticism 
Idiopathis

Question 10

Eosinopenia is associated with what?

Answer 10

Acute inflammation or corticosteroid. Alone it is no big deal

Question 11

Basophilia is seen with what?

Answer 11

Allergic/hypersensitivity issues: insect bites, drugs, or foods
Parasitism
Neoplasia