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Pharmocology > Pain Part 3 (Gout).pptx > Flashcards

Pain Part 3 (Gout).pptx Flashcards

1
Q

Which of the following are GOUT Drugs

a. Colchicine
b. Febuxostat
c. Allopurinol
d. Sumatriptain
e. Ergotamine
f. Probenecid

A

a. Colchicine
b. Febuxostat
c. Allopurinol
f. Probenecid

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2
Q

Fill in the blank ? the uric acid

A

CAP

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3
Q

Which means simply excessive uric acid that forms uric acid crystals in joints and tissue?

a. arthritis
b. gout

A

b. gout

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4
Q

What are the two main causes for gout?

a. Under-excretion - Kidneys
b. Under-excretion- Tumor Lysis Syndrome/ Diet induced-/ Excessive purines (hypoxanthine)
c. Over production- Tumor Lysis Syndrome/ Diet induced-/ Excessive purines (hypoxanthine)
d. Over production- Kidneys

A

a. Under-excretion - Kidneys

Over production- Tumor Lysis Syndrome/ Diet induced-/ Excessive purines (hypoxanthine)

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5
Q

What treat Gout and Uric acid?

a. NSAIDS
b. IV Corticosteroids
c. Colchicine
d. Allopurinol
e. Probenecid
f. Febuxostat

A

All

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6
Q

Which treats Chronic Gout

a. NSAIDS
b. IV Corticosteroids
c. Colchicine
d. Allopurinol
e. Probenecid
f. Febuxostat

A

d. Allopurinol

f. Febuxostat

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7
Q

Which treat acute gout

a. NSAIDS
b. IV Corticosteroids
c. Colchicine
d. Allopurinol
e. Probenecid
f. Febuxostat

A

b. IV Corticosteroids

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8
Q

Which Inhibit Xanthine oxidase- this is needed to make uric acid. End result- less uric acid

a. NSAIDS
b. IV Corticosteroids
c. Colchicine
d. Allopurinol
e. Probenecid
f. Febuxostat

A

d. Allopurinol

f. Febuxostat

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9
Q

Which has Hypersensitivity Reactions (SJS/TEN)

a. NSAIDS
b. IV Corticosteroids
c. Colchicine
d. Allopurinol
e. Probenecid
f. Febuxostat

A

d. Allopurinol

f. Febuxostat

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10
Q 
Which is Symptoms of Allopurinol
Skin Rash
Fever
Lips peeling
Mouth sores
Sore throat
Fatigue
A

All

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11
Q

Which can be used for Tumor Lysis Syndrome

a. NSAIDS
b. IV Corticosteroids
c. Colchicine
d. Allopurinol
e. Probenecid
f. Febuxostat

A

d. Allopurinol

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12
Q 
Which Deals with 
Higher risk of CV (Cardiovascularevents)
a. NSAIDS
b. IV Corticosteroids
c. Colchicine
d. Allopurinol
e. Probenecid
f. Febuxostat
A

f. Febuxostat

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13
Q

Which treat Acute Gout (Gout Flare Ups)

a. NSAIDS
b. IV Corticosteroids
c. Colchicine
d. Allopurinol
e. Probenecid
f. Febuxostat

A

c. Colchicine

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14
Q

Which Stops microtubules of WBCs, therefore stops WBCs from entering joints and attack gout crystals. If WBCs attack joints, they further increase inflammation

a. NSAIDS
b. IV Corticosteroids
c. Colchicine
d. Allopurinol
e. Probenecid
f. Febuxostat

A

c. Colchicine

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15
Q

Which is Chronic Gout

a. NSAIDS
b. IV Corticosteroids
c. Colchicine
d. Allopurinol
e. Probenecid
f. Febuxostat

A

e. Probenecid

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16
Q

ADVERSE EFFECTS:◦May target microtubules of our own rapidly multiplying cells. Early warning of this is GI symptoms, late warning is systemic organ damage- Death

a. NSAIDS
b. IV Corticosteroids
c. Colchicine
d. Allopurinol
e. Probenecid
f. Febuxostat

A

c. Colchicine

17
Q

Which Adverse Alters urine- so kidney stones, kidney injuries

a. NSAIDS
b. IV Corticosteroids
c. Colchicine
d. Allopurinol
e. Probenecid
f. Febuxostat

A

e. Probenecid

18
Q

Which Patients will be on this daily

a. NSAIDS
b. IV Corticosteroids
c. Colchicine
d. Allopurinol
e. Probenecid
f. Febuxostat

A

d. Allopurinol

e. Probenecid

19
Q

Promotion of Migraine

a. CGRP (calcitonin gene related peptide)
b. Serotonin (5-HT)

A

a. CGRP (calcitonin gene related peptide)

20
Q

Inhibition of Migraine

a. CGRP (calcitonin gene related peptide)
b. Serotonin (5-HT)

A

b. Serotonin (5-HT)

21
Q

Which Aborting an ongoing migraine attack to relieve headache and associated symptoms?

a. Sumatriptain- “Triptans”
b. Ergotamine

A

a. Sumatriptain- “Triptans”

22
Q

WHich is b. Serotonin (5-HT)

a. Sumatriptain- “Triptans”
b. Ergotamine

A

a. Sumatriptain- “Triptans”

23
Q

WHich is b. Serotonin (5-HT)

a. Sumatriptain- “Triptans”
b. Ergotamine

A

a. Sumatriptain- “Triptans”

24
Q

Which cause Chest pain?

a. Sumatriptain- “Triptans”
b. Ergotamine

A

a. Sumatriptain- “Triptans”

25
Q

Which Avoid in CAD, HTN, hx of MI, or other heart disease

a. Sumatriptain- “Triptans”
b. Ergotamine

A

a. Sumatriptain- “Triptans”

26
Q

Which Avoid in pregnancy

a. Sumatriptain- “Triptans”
b. Ergotamine

A

a. Sumatriptain- “Triptans”

27
Q 
Which should a patient avoid with Sumatriptain
Emotions
Certain Drugs
Lights/Noises
Certain Foods (besides Tyramine)
A

aall

28
Q

Sumatriptain should work orally with in ? min

and can be repeated in ? hours

A

1 min

1 -2

29
Q

Which Treat or abort an oncoming migraine

a. Sumatriptain- “Triptans”
b. Ergotamine

A

b. Ergotamine

30
Q

Which Causes vasoconstriction of cranial blood vessels

a. Sumatriptain- “Triptans”
b. Ergotamine

A

b. Ergotamine

31
Q

Do NOT give Ergotamine within ? hours of a triptan- the two together can cause extreme vasospastic reaction

A

24

32
Q

Ergotamine Adverse side effects

a. Physical Dependence (can have withdrawal- HA,N/V)
b. GI- N/V/D- give with food
c. Toxicity: Called Ergotism
d. Convulsions- seizures/spasms, muscle pain
e. Hallucinations- CNS
f. Extreme vasoconstriction to extremities (dry gangrene)

A

All

Pharmocology (36 decks)

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