Medication concept 1 Flashcards
with pregnancy can medication reach the fetus
Yes or No?
Yes
Does the first trimester or last trimester proposed the greatest risk
1st
Does the first trimester or last trimester has the highest drug absorption
Last
Which of the follwoing are drugs that can cross the placenta
Water soluble lipid soluble Small molecular weight Non-ionized Ionized
All except water and ionized
which breast feed you should not avoid long acting drugs
False
You sound give medication before or after breastfeeding
After
Some REM drugs that can cause infertility or teratogenic requires a (negative/Positve) pregnacy test and
Recommendations may include beginning or altering contraceptive therapies (T/F)
Neg
True
Ped
ABSORPTION
(decreased/increase) gastric acid production + (slower/faster) gastric emptying time
More/Less) blood flow to skin (topical drugs get rapidly absorbed)
Decrease
Slow
More
DISTRIBUTION
Limited protein binding sites (until age 1/2)
Still developing Blood Brain Barrier (drugs may/may not enter the brain)
(Higher/Lower) body water content (dilutes water soluble drugs)
1
may
High
METABOLISM
(Immature/ Mature) liver function
ELIMINATION
(Immature/Mature) kidney function
Immature
Immature
Match
? (doxycline) can bind to calcium of developing children
? ( levofloxacin) can damage developing cartilage
? (prednisone) can suppress or delay growth
Fluoroquinolones, Tetracyclines, Systemic Corticosteroids
Tetracyclines
Fluoroquinolones
Systemic Corticosteroids
Ped
Dose must be checked with weight (kg) or Body Surface Area (BSA) or Neither or Both
Both
GERIATRIC
ABSORPTION
(increase/decreased) gastric acid production + (slower/faster) gastric emptying time
Decreased
Slower
GERIATRIC
DISTRIBUTION
(Increased/Decreased) body water + (mass, more/less) fat content
(Increased/Decreased) protein binding
Decreased
More
Decreased
GERIATRIC METABOLISM◦ (Incline/Declined) liver function ELIMINATION (Incline/Declined) kidney function
Decline
Decline
