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Pharmocology > ANTI-FUNGAL DRUGS > Flashcards

ANTI-FUNGAL DRUGS Flashcards

1
Q

These Drugs are?
Amphotericin B/ Liposomal Amphotericin B
Nystatin

Azoles or Polyenes

A

Polyenes

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2
Q

These Drugs are?
Ketoconazole
Fluconazole

Azoles or Polyenes

A

Azoles

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3
Q

Candida albicans is bacteria or Fungus

A

Fungus

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4
Q

Fungus are Superficial or Systemic Infections or both

A

Both

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5
Q

Amphotericin B treat Superficial or Systemic Infections or both

A

Systemic Infections

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6
Q

? Binds to ergosterol in fungal cell membrane

Azoles Antifungal or Polyenes Antifungal drugs

A

Polyenes Antifungal drugs

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7
Q

Which Polyenens is highly toxic

Amphotericin B/ Liposomal Amphotericin B
Nystatin

A

Amphotericin B

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8
Q

Which causes causes fever, chills, rigors, muscle pain, nausea and headache around 1 to 3 hours after drug administration

Amphotericin B/ Liposomal Amphotericin B
Nystatin

A

Amphotericin B

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9
Q

Which causes a SHAKE AND BAKE”- INFUSION REACTION

Amphotericin B/ Liposomal Amphotericin B
Nystatin

A

Amphotericin B

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10
Q

Which cause adverse effects
Nephrotoxicity (Kidney)
Hypokalemia
Bone Marrow Suppression - RBCs(rare)

Amphotericin B/ Liposomal Amphotericin B
Nystatin

A

Amphotericin B/

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11
Q

Nystatin is treat Superficial or Systemic Infections or both

A

Superficial

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12
Q

Which deal with creams, oral suspension) THRUSH!!!!

Amphotericin B/ Liposomal Amphotericin B
Nystatin

A

Nystatin

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13
Q

Swish and Swallow” is used only when the thrush is inside the mouth.

T/F

A

True

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14
Q

Azole’s- Fluconazole & Ketoconazole are Superficial or Systemic Infections or both

A

Both

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15
Q

Inhibit fungal CYP450 enzymes

Azoles Antifungal or Polyenes Antifungal drugs

A

Azoles Antifungal

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16
Q

which prevent fungi from creating ergosterol

CYP450 enzymes or Liver Enzymes

A

CYP450 enzymes

17
Q

ADVERSE EFFECTS:
Primarily GI related- N/V/D

KETOCONAZOLE or FLUCONAZOLE

A

FLUCONAZOLE

18
Q

ADVERSE EFFECTS:
Hepatotoxicity
Sex hormone alteration (decreased libido, gynecomastia, menstrual irregularities)•GI related (N/V/D/C)

KETOCONAZOLE or FLUCONAZOLE

A

FLUCONAZOLE

19
Q

Which is used on the NCLEX more!

KETOCONAZOLE or FLUCONAZOLE

A

KETOCONAZOLE

20
Q

This medication class functions as a CYP inhibitor

Azoles Antifungal or Polyenes Antifungal drugs

A

Azoles Antifungal

21
Q

Which alters sex hormones- patients should report menstrual irregularities/decreased libido, gynecomastia

KETOCONAZOLE or FLUCONAZOLE

A

KETOCONAZOLE

22
Q

Which if taken orally ? you want to avoid H2RAs and PPIs- typically AVOID

Azoles Antifungal or Polyenes Antifungal drugs

A

Azoles Antifungal

23
Q

prazoles
No prazoles with the azoles
or
Yes prazoles with the azoles

Pharmocology (36 decks)

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