Endocrine Part 4-Adrenal.ppt Flashcards
Which are Glucocorticoids
a. prednisone
b. fludrocortisone
c. methylprednisolone
d. hydrocortisone
a. prednisone
c. methylprednisolone
d. hydrocortisone
Mineralocorticoids
a. prednisone
b. fludrocortisone
c. methylprednisolone
d. hydrocortisone
b. fludrocortisone
What is CORTICOSTEROIDS suffix ?
One
CORTICOSTEROIDS are secreted from?
a. Adrenal medulla
b. Adrenal cortex
b. Adrenal cortex
Aldosterone?
a. Glucocorticoids (?)
b. Mineralocorticoids (?)
b. Mineralocorticoids
Cortisol
a. Glucocorticoids (?)
b. Mineralocorticoids (?)
a. Glucocorticoids
Do CORTICOSTEROIDS deal with various sexual hormones?
Y/N
Yes
Cortisol level peak when?
a. Morning
b. Afternoon
C. Night time
a. Morning
Since cortisol natually peaks in the morning when should CORTICOSTEROIDS be given?
a. Morning
b. Afternoon
C. Night time
a. Morning
CORTICOSTEROIDS may inhibit or increase:
a. Metabolism
b. Inflammation
c. Both
c. Both
Which is true about Cortisol
a. Relieves stress
b. Stress hormone
c. Increases blood glucose during stress for survival
d. Decreases blood glucose during stress for survival
e. Fuel for brain
b. Stress hormone
c. Increases blood glucose during stress for survival
e. Fuel for brain
Which is true about Cortisol Metabolic Effects:
a. Gluconeogenesis- breakdown of proteins to amino acids
b. Hypertrophy is an increase and growth of muscle cells.
c. Lipolysis- increased free fatty acids
d. Decreased muscle mass,
e. Increased muscle mass,
f. Thinning of skin
g. Thicking of skin,
h. Hyperglycemia
i. Hypoglycemia
j. Moon face and buffalo hump
k. Decrease the breakdown of bone matrix (osteoporosis!)
m. Increase the breakdown of bone matrix (osteoporosis!)
a. Gluconeogenesis- breakdown of proteins to amino acids
c. Lipolysis- increased free fatty acids
d. Decreased muscle mass,
f. Thinning of skin
h. Hyperglycemia
j. Moon face and buffalo hump
m. Increase the breakdown of bone matrix (osteoporosis!)
Whats true about Cortisol Inflammation Effects:
a. It blocks Cyclo-oxygenase
b. It does’t block Cox 1 and Cox 2
c. It does block Cox 1 and Cox 2
d. It blocks prostaglandins similar to NSAIDS
e. It should be taken with food like NSAIDS
f. It Shouldn’t be taken with food like NSAIDS
a. It blocks Cyclo-oxygenase
c. It does block Cox 1 and Cox 2
d. It blocks prostaglandins similar to NSAIDS
e. It should be taken with food like NSAIDS
Which is true about Mineralocorticoids- aldosterone a. hypoglycemia b. hyperglycemia c. Hypercalcemia d. Hypocalcemia e. hypernatremia f. hyponatremia g. Sodium retention H. hypokalemia
b. hyperglycemia
d. Hypocalcemia
e. hypernatremia
g. Sodium retention
H. hypokalemia
Which is a disease that needs CORTICOSTEROIDS
a. Reye syndrome
b. Addison’s Disease
c. Kawasaki disease
b. Addison’s Disease
Which is lab values of low Cortisol
a. Hypoglycemia
b. Fatigue
c. Hypotension
d. Anorexia
e. N/V/D
f. Constipation
a. Hypoglycemia
b. Fatigue
c. Hypotension
d. Anorexia
e. N/V/D
Which are Glucocorticoids:
a. prednisone
b. fludrocortisone
c. methylprednisolone
d. hydrocortisone
a. prednisone
c. methylprednisolone
d. hydrocortisone
Which are Mineralocorticoids:
b. fludrocortisone
Which is LOW dose: physiologic effects?
a. prednisone
b. fludrocortisone
c. methylprednisolone
d. hydrocortisone
e. adrenal insufficiency
g. inflammation
a. prednisone
c. methylprednisolone
d. hydrocortisone
e. adrenal insufficiency
Which is HIGH dose: pharmacologic effects
a. prednisone
b. fludrocortisone
c. methylprednisolone
d. hydrocortisone
e. adrenal insufficiency
g. inflammation
a. prednisone
c. methylprednisolone
d. hydrocortisone
g. inflammation
treat adrenal insufficiency CHRONIC or ACUTE a. prednisone b. fludrocortisone c. methylprednisolone d. hydrocortisone
a. prednisone
c. methylprednisolone
d. hydrocortisoneA
CHRONIC
treat inflammation CHRONIC or ACUTE a. prednisone b. fludrocortisone c. methylprednisolone d. hydrocortisone
a. prednisone
c. methylprednisolone
d. hydrocortisone
ACUTE
Which treat the following: IBS, Crohns- GI Diseases Asthma, COPD- Pulmonary Poison Ivy, Rashes- Dermatology a. prednisone b. fludrocortisone c. methylprednisolone d. hydrocortisone
a. prednisone
c. methylprednisolone
d. hydrocortisone
Which treat the following: Adrenal Insufficiency- Endocrinology Rheumatoid Arthritis - Immunology Leukemia/Lymphomas - Hematology a. prednisone b. fludrocortisone c. methylprednisolone d. hydrocortisone
a. prednisone
c. methylprednisolone
d. hydrocortisone
Which treat the following: Joints- reduce inflammation Cerebral Edema Organ transplant (decrease immune response) a. prednisone b. fludrocortisone c. methylprednisolone d. hydrocortisone
a. prednisone
c. methylprednisolone
d. hydrocortisone
Which treat the following: Spinal cord injury Antiemetic NEONATES- Lung development a. prednisone b. fludrocortisone c. methylprednisolone d. hydrocortisone
a. prednisone
c. methylprednisolone
d. hydrocortisone
Whiich treats Addison’s Disease a. prednisone b. fludrocortisone c. methylprednisolone d. hydrocortisone
b. fludrocortisone
Which treats Orthostatic Hypotension a. prednisone b. fludrocortisone c. methylprednisolone d. hydrocortisone
b. fludrocortisone
C - U - S - H - I - N - G - O - I - D -
C –Cataracts U – Ulcers (peptic ulcer disease) S –Skin thinning/Striae, Salt retention H – Hypertension, Hirsutism I – Immunosuppression, Infections N – Necrosis of femoral heads] G – Glucose elevation/Glaucoma O – Osteoporosis, Obesity I – Impaired wound healing D – Depression/mood changes
Cortostreids Adverse Effects
a. hypokalemia
b. hyperkalemia
c. hyponatremia + water
d. hypernatremia + water
e. Hyperglycemia
f. Hypoglycemia
g. hyperlipidemia ( Elevated Cholesterol
h. hypolipidemia ( Decreased Cholesterol
i. Elevated WBC - Not getting outside blood, Increased j. Infections
k. Decreased WBC - Not getting outside blood, m. Increased Infections
a. hypokalemia
d. hypernatremia + water
e. Hyperglycemia
g. hyperlipidemia ( Elevated Cholesterol
i. Elevated WBC - Not getting outside blood, Increased j. Infections
Select what is true about Cortostreids
a. Take in the morning with food
b. Take in the afternoon without food
c. Patient are at risk for hyperglycemia, so check BG levels
d. Patient are at risk for hypoglycemia, so check BG levels
e. MUST TAPER (reduce dosage slowly) to prevent adrenal atrophy
f. Safe to with other people/crowds who may be SICK + LIVE VACCINES
g. AVOID other people/crowds who may be SICK
+ NO LIVE VACCINES
a. Take in the morning with food
c. Patient are at risk for hyperglycemia, so check BG levels
e. MUST TAPER (reduce dosage slowly) to prevent adrenal atrophyg. AVOID other people/crowds who may be SICK
+ NO LIVE VACCINES
Are the following: Cortosteriod Abnormal hair growth Thinning of the skin + Scarring Cushing’s Disease - fatty hump between the shoulders a. Short term effect b. Longterm effect
b. Longterm
Select what is true about Cortostreids
a. Children growth will remain normal
b. Children Growth may be delayed
c. Addison- do not need doses of steroids prior to stressful events
d. Addison- need doses of steroids prior to stressful events
e. Addison - Giving supplemental doses can prevent ADRENAL CRISIS
f. Addison - Giving supplemental doses can’t prevent ADRENAL CRISIS
b. Children Growth may be delayed
d. Addison- need doses of steroids prior to stressful events
e. Addison - Giving supplemental doses can prevent ADRENAL CRISIS
Which are low dose therapy for cortostreriods
a. Topical
b. PO
c. IV
d. Intranasal sprays
a. Topical
d. Intranasal sprays
Select what is true about Cortostreids
a. NSAIDS- can increase GI issues, peptic ulcer disease
b. NSAIDS- can decrease GI issues, peptic ulcer disease
c. Can be taken with Grape Juice
d. Can not be taken with Grape juice
a. NSAIDS- can increase GI issues, peptic ulcer disease
d. Can not be taken with Grape juice
Addison High Stress what is true?
a. EXTRA doses of steroids
b. LESS doses of steroids
c. Failure to do so can result in SHOCK and DEATH
d. SUPPLEMENTAL/EXTRA Doses of Steroids for Addison’s Patients
e. SUPPLEMENTAL/LOW Doses of Steroids for Addison’s Patients
f. Addison’s patients are supposed to wear bracelets in the event of an accident
a. EXTRA doses of steroids
c. Failure to do so can result in SHOCK and DEATH
d. SUPPLEMENTAL/EXTRA Doses of Steroids for Addison’s Patients
f. Addison’s patients are supposed to wear bracelets in the event of an accident