(P7) Skin pathology (Lab27) Flashcards
Identify

Molluscum contagiosum

Identify and Lable

Molluscum contagiosum
(circle) Scrab lesion-eosinophilic inclusion
(S2) Molluscum bodies (Poxyvirus) (eosinophilic inclusion cytoplasm-pink)-under/above epithelium
Note: Nuclei pushed to side

Identify

Seborrheic keratosis

Identify and Label
Seborrheic keratosis
(circled) Pseudo-horn cyst
(Blue stacked cells) Proliferation of Squamous Cells (Basal-like cells, hyperkeratosis, keratin-filled cycts on surface of tumor )
(red cicrcl) Horn-Cyst (fibroblast growth factor FGF-receprot)
(bottom red circl) proliferation of basolioid cell

Identify and Label

Keratoacanthoma
Squamous proliferation tuor mainly on
Hair-bearing skin (long lasting keloid)
(yellow) Tumor cell proliferation

Identify

Keratoacanthoma

Identify and label

Keratoacanthoma

Identify

Benign pilomatrixoma

Identify and label

Benign pilomatrixoma
(red circl) Intratumor caclification
Ghost cells
Shadow cells

Identify

Basal cell carcinoma

Identify and Label

Basal cell carcinoma

Identify

Pigmented compound nevus

Identify and Label

Pigmented compound nevus
(Blue circl) melanocyte- darker
(3sld) nest of melanocyte-surrounded by cleft

Identify

Malignant melanoma

Identify and label

Malignant melanoma
Ballonin cell

Identify

Keloid

Identify and Label

Keloid

Give an example of special staining helpful in detection of this lesion?

Keloid
-Van Gieson

Q. Malignant neoplasm that originates from the same tissue is?

Molluscum contagiosum
-Squamous cell carcinoma-

Q. Indicate the structure:
Large white/oval structure
Seborrheic keratosis
-Keratin filled cyst (horn cyst)-

Q. The pathological differential diagnosis of this lestion should include?

Keratoacanthoma
-Squamous cell carcinoma-

Q. This lesion typically occurs in the following age group?
Q. The lesion originates from what structure?
Q. List 2 benign skin tumors caused by viruses?
Q. Structure (Dark lower left) indicated on the slide is composed of?

Benign pilomatrixoma
- Children and young adults-
- Hair folicules-
- Verrucae, v. bulgaris, v. plantaris, v. plana, condyloma acuminatum, bowenoid papulosis, molluscum contagiousm-
- Calcium salt deposits-

Q. is this lestion malignant, semimalignant, or benign?

- Basal cell carcinoma*
- Semimalignant-

Q. This lesion typically unergoes slow evolution with time..name the lesion that represents the preceding and the next stage fo this evolution ?

- Basal cell carcinoma*
- -Marginal (junctinal) nevus-*
- -Dermal nevus-*

Q. The malignant counterpart of this lesion is called?

- Basal cell carcinoma*
- -Malignant melanoma-*

Q. The lesion direclty preceding this lesion is called?

- Pigmented compound nevus*
- Junctional nevus-

Q. Name 2 systems commonly used for the evaluation of local extent of this lesion?

- Malignant melanoma*
- -Clark (level of invasion)*
- -Breslow (tumor thickness)*
