(P6) Practical Q's

Question 1

• Most typical site of metastasis of gestational form*
• of this lesion:*
• Name 5*

Answer 1

Chorioncarcinoma

Lung

vagina

brain

liver

kidney

Question 2

Name structures from the top:

Answer 2

Ectopic tubal pregnancy

1. Decidua
   * 2. Villus*

• 3. Covered by double layer of trophoblast*
• 4. Smooth muscle*

Question 3

Most common vaginal malignant neoplasm in children

younger than 5 years of age:

Answer 3

Stromal sarcoma of the uterine corpus

• Sarcoma botryoides (embryonal rhabdomyosarcoma)

Question 4

Structure Indicated:

Answer 4

Abortion

Decidua – maternal portion of placenta,

• large stromal cells with distinct borders,*
• abundant cytoplasm and round nuclei*

1. Villi covered by 2 layers of cells (outer layer syncytiotrophoblast, inner layer cytotrophoblast)

2. Loose stroma of villi

-Chorionic villi with blood vessels

• ◦ The inner layer – cytotrophoblast – cuboidal cells*
• ◦ The outer layer – syncytiotrophoblast – multinucleated giant cells*

-Erythroblasts are visible in the stromal vessel

-Slide:

• decidua (large, pale pink cell with*
• distinct border and round nucleus)*
• Villi with erythroblasts.*
• some samples contain embryo: very*
• small and dark cells.*

Question 5

• 1. Definition:*
     
     2. Most typical clinical symptoms and signs

of this lesion are:

Answer 5

Adenomyosis

1. The presence of endometrial tissue in

the myometrium of the uterus

2. Menorrhagia

colicky dysmenorrhea

dysparunia

pelvic pain

Question 6

Give 4 examples of

ovarian sex-cord stromal tumors:

Answer 6

• Granulosa Cell Tumor*
• Fibroma-Thecoma*
• Sertoli-Leydig tumors*
• leydig cell tumors*

NOTE : Ovarian sex cord-stromal tumors (SCSTs) (table 1) are a group of benign and malignant neoplasms that develop from the sex cord (eg, Sertoli cell tumor, granulosa cell tumor) or stromal cells (eg, fibroma, thecoma, Leydig cell tumor) or both (eg, Sertoli-Leydig cell tumor)

Question 7

Give 4 most anatomical sites of

endometriosis:

Answer 7

Ovary

• rectovaginal septum
• laparotomy scars
• vagina
• falopian tube
• uterine ligament
• pelvic peritoneum
• umbilicus
• intestine
• abdominal cavity

Question 8

Anatomical structure on the slide is called:

Answer 8

Retinoblastoma (the eyeball)

• Lens

Question 9

• 1. Typical age of patients with this lesion is:*
     
     2. Structure presented by arrow ?

Answer 9

Fibroadenoma

1. 3rd decade; Young woman

2. proliferation of intralobular stroma distorts the epithelium

Question 10

Structures indicated by Arrow

Answer 10

Wilms Tumor (the kidney)

• Tightly packed blue cells (blastemal component)
• Interspersed tubules
• Glomeruli = Focal anaplasia (hyperchromatic, pleomorphic nuclei)

Question 11

Give examples of less common histological types

of

invasive breast carcinoma:

Answer 11

Invasive lobular carcinoma

• Medullary • Mucinous
• Tubular • Metaplastic

• Papillary

Question 12

Structure Indicated by the arrow:

Answer 12

Fibrocystic change

-Apocrine metaplasia

Question 13

Enlargement of the male breast is known as :

Answer 13

Gynecomastia

Question 14

Main risk factors of this lesion?

Answer 14

neonatal respiratory distress syndrome (RDS)

Prematurity

Cesarean

section

Multiple

gestation

Male Sex
Diabetes in mother

Question 15

What organs are affected by this condition?

Answer 15

epididymitis

• Scrotum contents • Testicles • Epididymus

Question 16

Most typical anatomical location of this lesion is:

Answer 16

Osteosarcoma

• Knee
• Seperate bones

Question 17

• According to WHO classification,*
• this lesion belongs to the following group of which tumors:*
• Identify structures from top:

Answer 17

Embryonal carcinoma of the testis

• Germ cell tumors

• 1-Alveolar / tubular / papillary apttern*
• 2-Large, hyperchromatic nucleus with nucleoli*

Question 18

Most typical anatomical location

of metastasis of this neoplasm:

Name Structures from top:

Answer 18

Adenocarcinoma of the prostate

• Spine
• Proximal femur • Pelvis
• Ribs

-Larger, benign glands-

-Small, crowded glands (adenoma)

-Prominent nucleoli…Single layer of cells

Question 19

1. Counterpart of this lesion:
2. Typical age of patients with this lesion:
3. Identify arrow structures from Top:

Answer 19

Seminoma of the testis

1. Dysgermioma

2. >50 Years Old

• Inflammatory cells
• septa
• Lobules of uniform cells

Question 20

Give an example of special staining helpful

in detection of this lesion:

-Identify image :

Answer 20

Metastatic gastric signet ring cell carcinoma in the ovary

• Mucicarmin • Alcian blue

-Signet ring cells are mucicarmine positive.

Question 21

Osteitis deformans (pagets disease)

could be associated with infection of the following organism:

Answer 21

• Paramyxoviruses (measles, RSV)

Question 22

Identify

Answer 22

Question 23

Most common malignant tumor of the penis is:

Answer 23

Squamous cell carcinoma

Question 24

1. What is another name for this lesion ?

Answer 24

“Dermoid cysts”

1. Teratoma of ovary