Other Lipid Lowering Drugs

Question 1

fibrates: mechanism of action

Answer 1

inhibition of cholesterol synthesis

Question 2

what is fibrates known for on the lipids

Answer 2

decrease in TG

Question 3

why do we want to lower TG

Answer 3

pancreatitis

Question 4

2 fibrates

Answer 4

gemfibrozil
fenofibrate

Question 5

what can we not wait gemfibrozil with

Answer 5

any statin because of rabdo

Question 6

fibrates effects

Answer 6

nausea, diarrhea, gall stones, phototoxicity

Question 7

what sequence do we focus on TG

Answer 7

pull blood
make sure TGs are not crazy high
meds for LDL
when LDL is fixed we check TG again

Question 8

ezetimide is a what

Answer 8

cholesterol absorbing inhibitor

Question 9

ezetimide affect on lipids

Answer 9

lowers LDL, increase HDL, small decrease in TG

Question 10

since ezetimide can only decrease LDL a small amount what do we pair it with

Answer 10

statins

Question 11

omega 3s are used for what

Answer 11

decrease triglycerides

Question 12

omega 3 adverse effects

Answer 12

prolonged bleeding, bruising

Question 13

omega 3 increase what

Answer 13

LDL by small amounts

Question 14

omega 3 are used for

Answer 14

pancreatitis

Question 15

statins lipid affects

Answer 15

major decrease in LDL
slight increase in HDL
slight increase in TG

Question 16

fibrates lipid affects

Answer 16

neutral on LDL
increase on HDL
major decrease on TG

Question 17

ezetimibe lipid affects

Answer 17

decrease LDL
increase HDL
neutral on TG

Question 18

omega 3 lipid affects

Answer 18

increase LDL
increase HDL
major decrease in TG