Beta 2 Receptor Agonists

Question 1

mechanism of action

Answer 1

stimulates B2 which cause smooth muslce relaxtion
most receptors are in bronchioles

Question 2

SABA vs LABA

Answer 2

SABA: work quicker, don’t last, rescue inhaler
LABA: don’t work quick, last long, preventative inhaler

Question 3

adverse effects

Answer 3

skeletal muscle tremor
tachycardia
nervousness
hypokalemia: relative= pushes K into cells so blood K drops

these are due to B2 stimulation else where besides lungs

Question 4

warnings about LABAs in asthma

Answer 4

hospitalization and death due to desensotivty
- must use steroid with LABA which eliminate attacks and make desnsitivty less likely to happen
- do not use as first defense
- shortest duration possible

Question 5

pros of inahlers

Answer 5

speed of onset is faster
fewer systematic adverse reactions

Question 6

cons to inhalers

Answer 6

increase systematic effects when inhaled incorrectly
benefits rely on technique
- use a spacer which creates smaller particles and get deeper into the lungs
- wait in-between doses because if having a bad attack is the first does opens the airways a little bit and then you can inhale more of the second dose

Question 7

SABA

Answer 7

albuterol

Question 8

LABA

Answer 8

salmeterol
formoterol
vilanterol

Question 9

what one is only use for COPD

Answer 9

vilaternol (due to long half life)