Anti BPH

Question 1

alpha 1 antagonists selective vs nonselective

Answer 1

nonselective work everywhere there is a alpha receptor (vessels)
selective only work in the prostate

Question 2

how do 5 alpha reductase inhibitors work

Answer 2

inhibits conversion of testosterone into DHT which is what causes glandular part of prostate to grow

Question 3

5 alpha reductase and a1 antagonists difference in onset of action

Answer 3

5a have full effects in 6-12 mo
a1 start working immediately

Question 4

advserse effect of a1 nonspecific and specific

Answer 4

both: decrease ejaculate volume
nonspecific: nasal congestion, fatigue, dizziness, fainting, orthostatic hypotension (due to activating alpha in vessels and causing vasodilation)

Question 5

5a adverse reactions

Answer 5

decrease ejaculate volume
decrease libido
gynecomastia

Question 6

who should not be in contact with 5a

Answer 6

pregnant women
this is beacause this is easily absorbed into the blood and DHT is vital for a developing male fetus

Question 7

a1 nonselective

Answer 7

terazosin
doxazosin
prazosin

Question 8

a1 selective

Answer 8

tamsulosin

Question 9

5a

Answer 9

finasteride