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Oral Pathology 2020 > Oral path Chapter 7 viral infections > Flashcards

Oral path Chapter 7 viral infections Flashcards

1
Q

What is HHV-3?

A

-Varicella-zoster virus (VZV)

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2
Q

What is HHV-4?

A

-Epstein-Barr virus

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3
Q

What is HHV-5?

A

-Cytomegalovirus

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4
Q

What is HHV-8?

A

-Kaposi’s sarcoma

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5
Q

What is the most common disease resulting from EBV exposure?

A

-Infectious mononucleosis

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6
Q

What are some other lesions/diseases that demonstrate EBV?

A
  • Oral hairy leukoplakia
  • Lymphomas
  • Lymphoproliferative disorders (African’s Burkitt’s lymphoma
  • Nasopharyngeal carcinoma
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7
Q

How is EBV infections spread?

A

-Intimate contact

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8
Q

What does a Diagnosis of EBV need to have?

A

-Presence of Paul-Bunnel heterophil antibodies

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9
Q

For the classical infection of mononucleosis what are some things to look for?

A
  • Fatigue
  • Malaise
  • Anorexia
  • Fever up to 104 and last 2 weeks
  • lymphadenopathy (tonsilar hyperplasia/cervical enlargement)
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10
Q

What oral lesions are associated with mono (EBV)?

A
  • Oropharyngeal tonsillar enlargement
  • Petechiae on hard palate
  • Necrotizing ulcerative gingivitis
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11
Q

What are enteroviruses classified into?

A
  • Echoviruses
  • Coxsackievirus
  • Poliovirus
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12
Q

What are three important diseases caused by coxsackievirus?

A
  • Herpangina
  • Hand-foot-and mouth disease
  • Acute lymphonodular pharyngitis
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13
Q

What type of signs and symptoms are associated with herpangina?

A
  • Skin rash
  • Sore throat
  • Fever
  • Oral lesions in the posterior mouth
  • Begin as red macules
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14
Q

What signs and symptoms are associated with hand foot and mouth disease?

A
  • Skin rash
  • oral lesions associated with flu like symptoms
  • Oral lesions arise first (larger than herpangia)
  • Affect buccal mucosa, labial mucosa, and tongue most commonly
  • Cutaneous lesions on borders of palms and soles
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15
Q

What signs and symptoms are associated with acute lymphonodular pharyngitis?

A
  • 1-5 yellow to dark pink nodules on the soft palate
  • Represent hyperplastic lymphoid aggregates
  • Fever
  • Sore throat
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16
Q

What causes Rubeola (measles)?

A

-Paramyxovirus

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17
Q

When do most cases of Rubeola arise?

A

-Winter

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18
Q

How is measles spread?

A

-Respiratory droplets

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19
Q

How many stages are there for measles?

A

3 stages for 3 days each

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20
Q

What occurs in the first stage of measles?

A
  • Coryza (runny nose)
  • Cough
  • Conjunctivitis
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21
Q

What stage of measles has the most distinctive oral manifestations, and what are these manifestations called?

A
  • First stage

- Koplik’s spots

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22
Q

What are Koplik’s spots?

A
  • Represent foci of epithelial necrosis
  • Pathognomonic
  • Multiple areas of mucosal erythema with numerous small, blue-white macules
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23
Q

What occurs in the second stage of measles?

A
  • Fever continues
  • Koplik’s spots fade
  • Maculopapular & erythematous rash begins (Starts with the face first)
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24
Q

What occurs in the third stage of measles?

A
  • Fever ends

- Rash fades

25
Q

What causes Rubella (german measles)?

A

-Togavirus

26
Q

What is congenital rubella syndrome?

A
  • Deafness
  • Heart disease
  • Cataracts
27
Q

What can rubella cause?

A

-Birth defects

28
Q

What oral lesions is associated with rubella?

A

-Forchheimer’s sign (small, discrete, dark-red papules on the palate)

29
Q

What is considered 9 day measles?

A

Rubeloa

30
Q

What is considered 3 day measles?

A

-Rubella

31
Q

What is a disease of exocrine glands?

A

-Mumps

32
Q

What exocrine glands are the best known sites of involvement for mumps?

A

-Salivary glands

33
Q

What do the involved glands of mumps exhibit?

A
  • Edema

- Lymphocytic infiltration

34
Q

What is the route of transmission for HIV?

A
  • Sexual contact
  • Parenteral exposure to blood
  • Transmission from mother to fetus
35
Q

What is the target cell for HIV?

A

-CD4 + Helper T lymphocyte

36
Q

What oral manifestations are strongly associated with HIV infections?

A
  • Candidiasis
  • Hairy leukoplakia (EBV) (white lesions bilateral on side of tongue)
  • Kapsi’s sarcoma
  • Non-Hodgkin’s lymphoma
  • Periodontal diseases
37
Q

What do you do for treatment with someone with HIV and candidiasis?

A

-Topical clotrimazole

38
Q

What is the most common EBV related lesions in AIDS pts?

A

-Oral Hairy leukoplakia

39
Q

What is characteristic of oral hairy leukoplakia?

A

-Found bilateral on lateral tongue, white plaque that doesn’t wipe off

40
Q

What is a multifocal neoplasm of vascular endothelial cell origin?

A

-Kaposi’s sarcoma

41
Q

What are the most common sites of Kaposi’s sarcoma?

A
  • Hard palate
  • Gingiva
  • Tongue
42
Q

HSV-1 is found where?

A

-Above the waste

43
Q

Where is HSV-2 found?

A

-Below the waste

44
Q

How do shingles present?

A

-Unilateral from dermatone

45
Q

What does HHV-3 reside?

A

-Dorsal root ganglion

46
Q

Where does HHV-1 reside?

A

-Trigeminal ganglion

47
Q

What is a herpetic whitlow?

A

-Herpetic paronychia is infection of the thumb or fingers

48
Q

What is the term for a primary herpes of HSV-1?

A

-Acute herpetic gingivostomatitis

49
Q

Where do recurrent herpes simplex happen intraoral lesions?

A

-On keratinized bound mucosa (palate, attached gingiva)

50
Q

What is the most common site of recurrence for HSV-1?

A

-Vermilion border

51
Q

If you are younger than 18 what is the name of primary HSV-1 infection?

A

-Gingivostomatitis

52
Q

If you are older than 19 what is the name of primary HSV-1 infections?

A

-Pharyngotonsillitis

53
Q

What are the histopathologic features of HSV?

A
  • Multinucleation
  • Ballooning degenerations
  • Tzanck cells
54
Q

If you have shingles impacting the tip of the nose is that a medical emergency?

A

-Yes can lead to blindness

55
Q

What is Ramsay Hunt Syndrome?

A
  • Cutaneous lesions of the external auditory canal
  • Involvement of ipsilateral face (facial paralysis, hearing defects, vertigo)
  • VZV
56
Q

What is another name for mumps?

A

-Epidemic parotitis

57
Q

What is Forchheimers sign associated with?

A

-Rubella

58
Q

What is swollen testicles associated with?

A

-Mumps

Oral Pathology 2020 (38 decks)

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