Chapter 12 lecture 3 soft tissue tumors Flashcards
What is multiple endocrine neoplasia characterized by?
- Parathyroid tumors
- Pituitary tumors
- Pancreatic tumors
- Adrenal gland tumors
- Thyroid tumors
- Mucosal neuromas
What are adrenal gland tumors also known as?
-Pheochromocytoma
What are thyroid tumors also known as?
-Medullary carcinoma
Patients with multiple endocrine neoplasia have what type of build?
- Marfanoid build (long thin face)
- Elongated limbs
What is the typically the first sign of multiple endocrine neoplasia?
-Oral mucosal neuromas
What are bilateral neuromas of the commissural mucosa highly characteristic of?
-Multiple endocrine neoplasia
What is a rare pigmented tumor that usually occurs during the 1st year of life?
-Melanotic neuroectodermal tumor of infancy
What does a melanotic neuroectodermal tumor of infancy appear as clinically?
-Black and or blue rapidly expanding mass usually found on the anterior maxilla
How do they diagnose melanotic neuroectodermal tumor of infancy?
-Test for high urinary levels of vanillymandelic acid
What is a granular cell tumor?
-Benign soft tissue neoplasm that shows a predilection for the oral cavity
What is the most common site for a granular cell tumor?
-Tongue with the dorsal surface being the most common
What does a granular cell tumor appear as clinically?
-Yellow or mucosal colored, asymptomatic sessile nodule that is less than than 2 cm.
What can a granular cell tumor cause?
-Pseudoepitheliomatous hyperlasia (also caused by blastomycosis)
What is S-100 positive associated with: granular cell tumor or congenital epulis?
-Granular cell tumor
What can occur almost exclusively on the alveolar ridge of newborns?
-Congenital epulis
What does a congenital epulis appear as clinically?
-Mucosal colored, smooth surfaced, polypoid mass typically less than 2 cm
What arch do you typically see a congenital epulis?
-Maxillary on the ridge
What differentiates a congenital epulis from a granular cell tumor?
-a congenital epulis does not have PEH (pseudoepithelomatous hyperlasia) and is S-100 negative
What gender does a congenital epulis most commonly occur in?
-Female