Chapter 12 lecture 3 soft tissue tumors Flashcards

1
Q

What is multiple endocrine neoplasia characterized by?

A
  • Parathyroid tumors
  • Pituitary tumors
  • Pancreatic tumors
  • Adrenal gland tumors
  • Thyroid tumors
  • Mucosal neuromas
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2
Q

What are adrenal gland tumors also known as?

A

-Pheochromocytoma

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3
Q

What are thyroid tumors also known as?

A

-Medullary carcinoma

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4
Q

Patients with multiple endocrine neoplasia have what type of build?

A
  • Marfanoid build (long thin face)

- Elongated limbs

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5
Q

What is the typically the first sign of multiple endocrine neoplasia?

A

-Oral mucosal neuromas

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6
Q

What are bilateral neuromas of the commissural mucosa highly characteristic of?

A

-Multiple endocrine neoplasia

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7
Q

What is a rare pigmented tumor that usually occurs during the 1st year of life?

A

-Melanotic neuroectodermal tumor of infancy

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8
Q

What does a melanotic neuroectodermal tumor of infancy appear as clinically?

A

-Black and or blue rapidly expanding mass usually found on the anterior maxilla

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9
Q

How do they diagnose melanotic neuroectodermal tumor of infancy?

A

-Test for high urinary levels of vanillymandelic acid

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10
Q

What is a granular cell tumor?

A

-Benign soft tissue neoplasm that shows a predilection for the oral cavity

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11
Q

What is the most common site for a granular cell tumor?

A

-Tongue with the dorsal surface being the most common

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12
Q

What does a granular cell tumor appear as clinically?

A

-Yellow or mucosal colored, asymptomatic sessile nodule that is less than than 2 cm.

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13
Q

What can a granular cell tumor cause?

A

-Pseudoepitheliomatous hyperlasia (also caused by blastomycosis)

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14
Q

What is S-100 positive associated with: granular cell tumor or congenital epulis?

A

-Granular cell tumor

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15
Q

What can occur almost exclusively on the alveolar ridge of newborns?

A

-Congenital epulis

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16
Q

What does a congenital epulis appear as clinically?

A

-Mucosal colored, smooth surfaced, polypoid mass typically less than 2 cm

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17
Q

What arch do you typically see a congenital epulis?

A

-Maxillary on the ridge

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18
Q

What differentiates a congenital epulis from a granular cell tumor?

A

-a congenital epulis does not have PEH (pseudoepithelomatous hyperlasia) and is S-100 negative

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19
Q

What gender does a congenital epulis most commonly occur in?

A

-Female

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20
Q

What is the most common tumor of infancy?

A

-Hemangioma

21
Q

What is the most common location for a hemangioma?

A

-Head and neck

22
Q

What are the two types of hemangiomas?

A
  • Capillary

- Cavernous

23
Q

What might you do to tell if it is a capillary hemangioma?

A

-May not blanch clinically and is usually red in color

24
Q

What might you do to tell if it is a cavernous hemangioma?

A

-Typically blanches, and is a darker red to purple color

25
Q

What is a rare, nonhereditary developmental condition caused by the persistence of a vascular plexus around the cephalic portion of the neural tube?

A

-Sturge-Weber Angiomatosis

26
Q

Patients with sturge-weber angiomatosis are born with a dermal capillary vascular malformation known as what?

A
  • Port wine stain

- Nevus flammeus

27
Q

T/F if a pt has port wine stain they have sturge-weber angiomatosis

A

False

-Not all people with the stain have sturge weber angiomatosis

28
Q

T/F Sturge-weber angiomatosis is unilateral and is usually associated with the trigeminal nerve

A

True

29
Q

What is a benign tumor of lymphatic vessels?

A

-Lymphangioma

30
Q

What are the types of lymphangioma?

A
  • Capillary
  • Cavernous
  • Cystic
31
Q

Where are cavernous lymphangiomas more frequently found?

A

-In the mouth

32
Q

What are cystic lymphangiomas most often found?

A

-Lateral Neck

33
Q

Oral lymphangiomas occur most frequently where?

A

-Anterior two thirds of the tongue resulting often in macroglossia

34
Q

What age do most cases of lymphangiomas occur?

A

-Before 2 yrs of age

35
Q

What is a benign tumor of smooth muscle?

A

-Leiomyoma

36
Q

What is the most common location of Leiomyoma?

A
  • Uterus
  • GI tract
  • Skin
37
Q

What is a benign neoplasm of skeletal muscle?

A

-Rhabdomyoma

38
Q

Who does the adult type of Rhabdomyoma occur in?

A

-Men

39
Q

In adult Rhabdomyoma where does it most commonly occur?

A
  • Pharynx

- FOM

40
Q

In fetal Rhabdomyoma who and where does it occur?

A
  • Young male pts

- Predilection for the face

41
Q

What are six soft tissue sarcomas?

A
  • Fibrosarcoma
  • Malignant fibrous histiocytoma
  • Liposarcoma
  • Leiomyosarcoma
  • Angiosarcoma
  • Malignant peripheral nerve sheath tumor
42
Q

What are the four clinical presentations of Kaposi’s sarcoma?

A
  • Classic
  • Endemic
  • Iatrogenic immunosuppression associated
  • AIDS related
43
Q

What ethnicities can get the classic kaposi’s sarcoma?

A
  • Italian
  • Jewish
  • Slavic descent
44
Q

Where is the endemic type of kaposi’s sarcoma found?

A

-Africa

45
Q

What is a malignancy of skeletal muscles?

A

-Rhabdomyosarcoma

46
Q

Where are the most common locations of Rhabdomyosarcoma?

A

-Face and orbit in children

47
Q

Head and neck metastases in the absence of lung metastases is possible because of what?

A

-Batson’s plexus

48
Q

What is Batson’s plexus?

A

-Valveless vertebral venous plexus that might allow retrograde spread of tumor cells and bypass the lungs

49
Q

What is the most common site for metastases to the soft tissues?

A

-Gingiva