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Oral Pathology 2020 > Chapter 17 Oral Manifestations of Systemic Diseases > Flashcards

Chapter 17 Oral Manifestations of Systemic Diseases Flashcards

1
Q

What is jaundice?

A

-Excess bilirubin in the bloodstream accumulates in the tissues

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2
Q

Elastin fibers have an affinity for bilirubin, what areas are more prominently affected?

A
  • Sclera
  • Lingual frenum
  • Soft palate
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3
Q

What is a group of conditions characterized by the deposition of an extracellular, proteinaceous substance termed amyoild?

A

-Amyloidosis

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4
Q

What other disease is associated with primary systemic amyloidosis?

A

-Multiple Myeloma

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5
Q

What is secondary amyloidosis associated with?

A

-Hemodialysis

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6
Q

When you have organ limited amyloidosis does it occur in the oral cavity?

A

-Very rarely

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7
Q

What is the cause of 20% of primary systemic amyloidosis?

A

-Multiple myeloma

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8
Q

What are the most common areas affected by primary systemic amyloidosis?

A
  • Eyelid
  • Neck
  • Lips
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9
Q

What does secondary systemic amyloidosis develop as a result of?

A
  • Chronic inflammatory process such as TB, sarcoidosis, or osteomyelitis
  • Hemodialysis
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10
Q

What is Vitamin A?

A

-Retinol

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11
Q

What is Vitamin A essential for?

A

-Vision

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12
Q

What might a Vitamin A deficiency lead to>?

A

-Blindness

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13
Q

What is Vitamin B1?

A

-Thiamin

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14
Q

What is Vitamin B1 used for?

A

-maintain proper functioning of neurons

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15
Q

What does a Vitamin B1 deficiency lead to?

A

-Beriberi

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16
Q

What is Vitamin B2?

A

-Riboflavin

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17
Q

What is Vitamin B2 necessary for?

A

-Cellular oxidation-reduction reactions

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18
Q

What happens if you have a Vitamin B2 deficiency?

A

-Oral alterations like angular cheilitis or glossitis

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19
Q

What is Vitamin B3?

A

-Niacin

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20
Q

What does Vitamin B3 do?

A

-Acts as a coenzyme for oxidation-reduction reactions

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21
Q

What happens if you have a Vitamin B3 deficiency?

A

-Pellagra = dermatitis, dementia, and diarrhea

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22
Q

What is Vitamin B6?

A

-Pyridoxine

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23
Q

What is Vitamin B6 used for?

A

-Cofactor associated with enzymes that participate in Amino Acid synthesis

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24
Q

What is Vitamin C?

A

-Ascorbic acid

25
Q

What is Vitamin C necessary for?

A

-Proper synthesis of collagen

26
Q

What occurs with a Vitamin C deficiency?

A

-Scurvy

27
Q

Vitamin D is considered a what?

A

-Hormone

28
Q

What is Vitamin D necessary for?

A

-Calcium absorption from the gut

29
Q

What does Vitamin D deficiency result in adults and kids?

A
  • Osteomalacia

- Rickets (kids)

30
Q

What is Vitamin E?

A

-Alpha-tocopherol

31
Q

What is Vitamin E used for?

A

-Antioxidant

32
Q

What is vitamin K necessary for?

A

-Proper clotting

33
Q

What are vitamin K clotting factors?

A
  • II
  • VII
  • IX
  • X
34
Q

What occurs if you are vitamin K deficient?

A

-Coagulopathy because of inadequate synthesis or prothrombin

35
Q

What is the most common cuase of anemia in the US and the world?

A

-Iron deficiency anemia

36
Q

How does Iron deficiency anemia develop?

A
  • Excessive blood loss
  • Increased demand for RBCs
  • Decreased uptake of iron
  • Decreased absorption of iron
37
Q

What are oral manifestations of Iron deficiency anemia?

A
  • angular cheilitis

- atrophic glossitis

38
Q

What syndrome is associated with Iron-deficiency anemia?

A

-Plummer-Vinson syndrome

39
Q

What characterizes Plummer-Vinson Syndrome?

A
  • Irone deficiency anemia
  • Glossitis
  • Dysphagia
40
Q

T/F Plummer-Vinson Syndrome is considered a premalignant process

A

True

41
Q

What is another sign of Plummer-Vinson syndrome?

A

-alterations of growth pattern of the nails that results in spoon-shaped configuration (koilonychia)

42
Q

What is type of anemia is Pernicious anemia?

A

-Megaloblastic anemia

43
Q

What causes Megaloblastic (pernicious anemia)?

A

-Poor absorption of cobalamin (Vitamin B12)

44
Q

Is Vitamin B12 an intrinsic or extrinsic factor?

A

-Intrinsic

45
Q

What are the oral manifestations of Pernicious anemia?

A

-Atrophic glossitis

46
Q

What disease is associated with an increased production of GH usually related to a functioning pituitary adenoma?

A

-Gigantism

47
Q

What oral findings are associated with Gigantism?

A

-Generalized macrodontia

48
Q

When does gigantism take place?

A

-Before the closure of the epiphyseal plates

49
Q

When does acromegaly occur?

A

-After closure of the epiphyseal paltes

50
Q

What is acromegaly?

A

-Excessive production of GH after closure of epiphyseal plates

51
Q

What is Hypothyroidism in infancy known as?

A

-Cretinism

52
Q

What is Hypothyroidism in adulthood known as?

A

-Myxedema

53
Q

What deep fungal infection is associated with uncontrolled diabetes?

A

-Zygomycosis

54
Q

What type of Diabetes are oral manifestations associated with?

A

-Type I

55
Q

What oral manifestations do you see with Type I DM?

A
  • Periodontal disease
  • Delayed healing
  • Increased infections
  • Enlargement of erythema of the attached gingiva
  • Oral candidiasis
56
Q

What is an inflammatory and immunologically mediated condition of unknown cause?

A

-Crohn’s disease

57
Q

What are the oral lesions of Crohn’s disease?

A

-Linear ulcer of the buccal vestibule

58
Q

What do the oral lesions of Crohn’s disease look like?

A

-Cobblestone appearance

Oral Pathology 2020 (38 decks)

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