Chapter 14 Bone pathology Flashcards
What are some ways to determine if it is a benign bone neoplasm?
- Asymptomatic
- Grows slowly by expansion moving teeth
- Symmetrical
- Does not metastasize
What are some ways to determine if it is a malignant bone neoplasm?
- usually symptomatic
- Grows more rapidly
- Invades and destroys adjacent structure
- Often asymmetrical
- Ragged or poorly defined margins
- Laying down bone outside the cortex
What is the most common type of inherited bone disease?
-Osteogenesis imperfecta
What does osteogenesis imperfecta have a defect in?
-Type I collagen maturation
What are signs and symptoms of osteogenesis imperfecta?
- Bone fragility
- Blue sclera
- altered teeth
- Hearing loss
- Long bone and spine deformities
- Join hyper extensibility
What are wormian bones in the skull?
-Abnormal sutures found with osteogenesis imperfecta
What are some distinctive occasional findings noted in the oral cavity associated with osteogenesis imperfecta?
- Teeth with a blue to brown translucence
- Premature pulpal obliteration
- Class III malocclusion
What is marble bone disease?
-Ostopetrosis
What is a skeletal disorder with a marked increase in bone density?
-Osteopetrosis
T/F Osteopetrosis is a failure of normal osteoclast function
True
What are the XRAY features of osteopetrosis?
- Widespread increase in skeletal density (Increased radiopaque)
- Roots of teeth are difficult to visualize because of the density of surrounding bone
What is a syndrome complex characterized by dental and clavicle abnormalities?
-Cleidocranial dysplasia
What are oral feature of cleidocranial dysplasia?
-Numerous unerupted permanent and supernumerary teeth
What is an area of hematopoietic marrow that produces a roadiolucency?
-Focal osteoporotic marrow defect
T/F Focal osteoporotic marrow defect has no association between focal osteoporotic marrow defect and any hematologic disorder
True