Chapter 14 Bone pathology Flashcards
What are some ways to determine if it is a benign bone neoplasm?
- Asymptomatic
- Grows slowly by expansion moving teeth
- Symmetrical
- Does not metastasize
What are some ways to determine if it is a malignant bone neoplasm?
- usually symptomatic
- Grows more rapidly
- Invades and destroys adjacent structure
- Often asymmetrical
- Ragged or poorly defined margins
- Laying down bone outside the cortex
What is the most common type of inherited bone disease?
-Osteogenesis imperfecta
What does osteogenesis imperfecta have a defect in?
-Type I collagen maturation
What are signs and symptoms of osteogenesis imperfecta?
- Bone fragility
- Blue sclera
- altered teeth
- Hearing loss
- Long bone and spine deformities
- Join hyper extensibility
What are wormian bones in the skull?
-Abnormal sutures found with osteogenesis imperfecta
What are some distinctive occasional findings noted in the oral cavity associated with osteogenesis imperfecta?
- Teeth with a blue to brown translucence
- Premature pulpal obliteration
- Class III malocclusion
What is marble bone disease?
-Ostopetrosis
What is a skeletal disorder with a marked increase in bone density?
-Osteopetrosis
T/F Osteopetrosis is a failure of normal osteoclast function
True
What are the XRAY features of osteopetrosis?
- Widespread increase in skeletal density (Increased radiopaque)
- Roots of teeth are difficult to visualize because of the density of surrounding bone
What is a syndrome complex characterized by dental and clavicle abnormalities?
-Cleidocranial dysplasia
What are oral feature of cleidocranial dysplasia?
-Numerous unerupted permanent and supernumerary teeth
What is an area of hematopoietic marrow that produces a roadiolucency?
-Focal osteoporotic marrow defect
T/F Focal osteoporotic marrow defect has no association between focal osteoporotic marrow defect and any hematologic disorder
True
What is a focal area of increased radiodensity that is of unknown cause and cannot be attributed to anything else?
-Idiopathic osteosclerosis
What might idiopathic osteosclerosis be confused with?
- Condensing osteitis
- Cemento-osseous dysplasia
- Cementoblastoma
How do you distinguish a cemento-osseous dysplasia vs idiopathic osteosclerosis?
-Cemento-osseous dysplasias will have a radiolucent rim
How do you known it is a cementoblastoma?
-Fused with the tooth
How do you know if it condensing osteitis?
-Associated with infection
Do you see idiopathic osteosclerosis more in the mandible or maxilla?
-Mandible
What is a relatively common disease characterized by abnormal resorption and deposition of bone?
-Paget’s disease of bone
What is a common complaint of paget’s disease of bone?
-Bone pain
What can cause bone growth to the point where a denture doesn’t fit any more?
-Paget’s disease of bone
What is leontiasis ossea associated with?
-Paget’s disease of bone
What are the Xray features associated with paget’s disease of bone?
- Many teeth with hypercementosis
- Patchy sclerotic areas have a cotton wool appearance
What test do you run to determine paget’s disease of bone?
-Serum alkaline phosphatase levels
What is considered a on neoplastic lesion that crosses the midline?
-Central Giant cell granuloma
Where is a central giant cell granuloma more commonly found?
-The anterior jaw
What two other things does the histopathology of a central giant cell granuloma appear as?
- Brown tumor of hyperparathyroidism
- Lesions of cherubism
What is a developmental jaw condition?
-Cherubism
What causes the eyes upturned to heaven in cherubism?
-Wide rim of exposed sclera noted below the iris
What is a traumatic bone cyst also known as?
-Simple bone cyst
Is a traumatic bone cyst a true cyst?
-No because it does not have an epithelial lining
What can cause a traumatic bone cyst?
-Trauma hemorrhage theory
When several teeth are involved in traumatic bone cyst what does the defect show up like in an xray?
-Domelike projections that scallop between the roots
What is an aneurysmal bone cyst?
- It is not a true cyst
- An intraosseous accumulation of blood-filled spaces surrounded by connective tissue
What does the clinical appearance of an aneurysmal bone cyst?
-Blood soaked sponge
A pt presents with central giant cell granuloma what other diseases should you consider?
- Cherubism
- Browns tumor of hyperparathyroidism
