Chapter 14 Bone pathology Flashcards

1
Q

What are some ways to determine if it is a benign bone neoplasm?

A
  • Asymptomatic
  • Grows slowly by expansion moving teeth
  • Symmetrical
  • Does not metastasize
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2
Q

What are some ways to determine if it is a malignant bone neoplasm?

A
  • usually symptomatic
  • Grows more rapidly
  • Invades and destroys adjacent structure
  • Often asymmetrical
  • Ragged or poorly defined margins
  • Laying down bone outside the cortex
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3
Q

What is the most common type of inherited bone disease?

A

-Osteogenesis imperfecta

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4
Q

What does osteogenesis imperfecta have a defect in?

A

-Type I collagen maturation

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5
Q

What are signs and symptoms of osteogenesis imperfecta?

A
  • Bone fragility
  • Blue sclera
  • altered teeth
  • Hearing loss
  • Long bone and spine deformities
  • Join hyper extensibility
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6
Q

What are wormian bones in the skull?

A

-Abnormal sutures found with osteogenesis imperfecta

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7
Q

What are some distinctive occasional findings noted in the oral cavity associated with osteogenesis imperfecta?

A
  • Teeth with a blue to brown translucence
  • Premature pulpal obliteration
  • Class III malocclusion
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8
Q

What is marble bone disease?

A

-Ostopetrosis

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9
Q

What is a skeletal disorder with a marked increase in bone density?

A

-Osteopetrosis

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10
Q

T/F Osteopetrosis is a failure of normal osteoclast function

A

True

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11
Q

What are the XRAY features of osteopetrosis?

A
  • Widespread increase in skeletal density (Increased radiopaque)
  • Roots of teeth are difficult to visualize because of the density of surrounding bone
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12
Q

What is a syndrome complex characterized by dental and clavicle abnormalities?

A

-Cleidocranial dysplasia

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13
Q

What are oral feature of cleidocranial dysplasia?

A

-Numerous unerupted permanent and supernumerary teeth

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14
Q

What is an area of hematopoietic marrow that produces a roadiolucency?

A

-Focal osteoporotic marrow defect

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15
Q

T/F Focal osteoporotic marrow defect has no association between focal osteoporotic marrow defect and any hematologic disorder

A

True

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16
Q

What is a focal area of increased radiodensity that is of unknown cause and cannot be attributed to anything else?

A

-Idiopathic osteosclerosis

17
Q

What might idiopathic osteosclerosis be confused with?

A
  • Condensing osteitis
  • Cemento-osseous dysplasia
  • Cementoblastoma
18
Q

How do you distinguish a cemento-osseous dysplasia vs idiopathic osteosclerosis?

A

-Cemento-osseous dysplasias will have a radiolucent rim

19
Q

How do you known it is a cementoblastoma?

A

-Fused with the tooth

20
Q

How do you know if it condensing osteitis?

A

-Associated with infection

21
Q

Do you see idiopathic osteosclerosis more in the mandible or maxilla?

A

-Mandible

22
Q

What is a relatively common disease characterized by abnormal resorption and deposition of bone?

A

-Paget’s disease of bone

23
Q

What is a common complaint of paget’s disease of bone?

A

-Bone pain

24
Q

What can cause bone growth to the point where a denture doesn’t fit any more?

A

-Paget’s disease of bone

25
Q

What is leontiasis ossea associated with?

A

-Paget’s disease of bone

26
Q

What are the Xray features associated with paget’s disease of bone?

A
  • Many teeth with hypercementosis

- Patchy sclerotic areas have a cotton wool appearance

27
Q

What test do you run to determine paget’s disease of bone?

A

-Serum alkaline phosphatase levels

28
Q

What is considered a on neoplastic lesion that crosses the midline?

A

-Central Giant cell granuloma

29
Q

Where is a central giant cell granuloma more commonly found?

A

-The anterior jaw

30
Q

What two other things does the histopathology of a central giant cell granuloma appear as?

A
  • Brown tumor of hyperparathyroidism

- Lesions of cherubism

31
Q

What is a developmental jaw condition?

A

-Cherubism

32
Q

What causes the eyes upturned to heaven in cherubism?

A

-Wide rim of exposed sclera noted below the iris

33
Q

What is a traumatic bone cyst also known as?

A

-Simple bone cyst

34
Q

Is a traumatic bone cyst a true cyst?

A

-No because it does not have an epithelial lining

35
Q

What can cause a traumatic bone cyst?

A

-Trauma hemorrhage theory

36
Q

When several teeth are involved in traumatic bone cyst what does the defect show up like in an xray?

A

-Domelike projections that scallop between the roots

37
Q

What is an aneurysmal bone cyst?

A
  • It is not a true cyst

- An intraosseous accumulation of blood-filled spaces surrounded by connective tissue

38
Q

What does the clinical appearance of an aneurysmal bone cyst?

A

-Blood soaked sponge

39
Q

A pt presents with central giant cell granuloma what other diseases should you consider?

A
  • Cherubism

- Browns tumor of hyperparathyroidism