Chapter 9 Allergies and immunologic diseases Flashcards

1
Q

What are the three patterns of transient lingual papillitis?

A
  • Localized
  • Generalized
  • Diffuse, papulokeratotic variant
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2
Q

What does transient lingual papillitis appear as?

A

-Large red/yellow papilla

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3
Q

For symptomatic transient lingual papillitis what might help reduce the pain?

A

-Topical steroids

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4
Q

What are recurrent aphthous ulcerations aka?

A

-Recurrent aphthous stomatitis (canker sores)

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5
Q

Where do recurrent aphthous ulcers occur exclusively?

A

-Movable mucosa

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6
Q

What are the three clinical variations of Recurrent aphthous ulcers?

A
  • Minor
  • Major
  • Herpetiform
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7
Q

When does RAU occur?

A

-Childhood

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8
Q

What is the most common form of RAU?

A

-Minor

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9
Q

T/F Pats with RAU minor typically have a prodrome

A

True

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10
Q

What does RAU minor appear as in size?

A

-Less than 1 cm

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11
Q

How fast does RAU minor heal?

A

-7-10 days spontaneously

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12
Q

Who does RAU major occur in?

A

-Adolescents

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13
Q

What does RAU major appear as in size?

A

1-3 cm

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14
Q

What type of RAU has the longest duration per episode?

A

-Major

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15
Q

How long does it take RAU to heal?

A

2-6 weeks

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16
Q

T/F RAU major may cause scarring

A

True

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17
Q

How many lesions per episode do you get in RAU Minor?

A

-1-5

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18
Q

How many lesions per episode do you get in RAU major?

A

1-10

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19
Q

What are the most commonly involved locations of RAU major?

A
  • Labial mucosa
  • Soft palate
  • Tonsillar fauces
20
Q

What is major aphthus uclers aka?

A

-Suttons disease

21
Q

Who does RAU herpetiform occur in?

A

Adults

22
Q

What type of RAU occurs in greatest numbers of lesions and recurrences?

A

-Herpetiform stomatitis

23
Q

What is the size of herpetiform RAU?

A

1-3 mm

24
Q

What is the healing time of herpetiform RAU?

A

7-10 days

25
Q

Which type of RAU is scarring possible?

A

-Major

26
Q

How many lesions are possible for RAU herpetiform?

A

-up to 100

27
Q

What is a chronic recurrent immune mediated disease with oral aphthous like ulcerations, ocular inflammation, genital ulcers and skin lesions?

A

-Behcet’s syndrome

28
Q

What is associated with Behcet’s syndrome?

A
  • Ocular inflammation
  • Genital ulcers
  • Oral aphthous-like ulcers
  • Joint pain
29
Q

What is the treatment for Behcet’s syndrome?

A

-Systemic and topical steroids

30
Q

What is a multisystem granulomatous disorder of unknown cause?

A

-Sarcoidosis

31
Q

What organs are most commonly involved in sarcoidosis?

A
  • Lungs
  • Lymph nodes
  • Skin
  • Eyes
  • Salivary glands
32
Q

T/F Lymphoid tissue is involved in almost all cases of sarcoidosis

A

True

33
Q

What pt is most likely to have sarcoidosis?

A

-African Americans

34
Q

What are two different syndromes associated with sarcoidosis?

A
  • Lofgren’s syndrome

- Heerfordt’s syndrome

35
Q

If you have sarcoidosis on the skin what is it termed?

A

-Lupus pernio

36
Q

If you have scattered, nonspecific, tender, red nodules on lower legs, what is that termed?

A

-Erythema nodosum

37
Q

What is associated with Lofgren’s syndrome?

A
  • Erythema nodosum
  • Bilateral hilar lymphadenopathy
  • Arthralgia (joint pain)
38
Q

What is associated with Heerfordt’s syndrome?

A
  • Parotid enlargement
  • Inflammation of eye
  • Facial paralysis
  • Fever
  • aka uveoparotid fever
39
Q

What are the histological features of Sarcoidosis?

A
  • Granulomatous inflammation
  • Schaumann bodies
  • Asteroid bodies
  • Hamazaki-Wesenberg bodies
40
Q

What is needed to diagnose sarcoidosis?

A
  • Elevated serum angiotensin-converting enzyme levels
  • Chest XRAY
  • Kveim test
41
Q

When only the lips are involved with orofacial granulomatosis what is that known as?

A

-Cheilitis granulomatosa

42
Q

What is Melkersson-Rosenthal syndrome?

A
  • Cheilitis granulomatosa
  • Facial paralysis
  • Fissured tongue
43
Q

What does classic Wegner’s granulomatosis have associated with it?

A
  • Necrotizing granulomatous lesions of respiratory tract,
  • necrotizing glomerulonephritis
  • Systemic vasculitis of small arteries and veins
44
Q

What are the oral lesions are characteristic of wegner’s granulomatosis?

A

-Strawberry gingivitis

45
Q

How do you diagnose Wegner’s granulomatosis?

A

-Indirect immunofluorescence detecs presence of antineutrophil cytoplasm antibodies (cytoplasmic)

46
Q

If wegner’s granulomatosis goes untreated what is the prognosis?

A

-10% two year survival