Chapter 9 Allergies and immunologic diseases Flashcards
What are the three patterns of transient lingual papillitis?
- Localized
- Generalized
- Diffuse, papulokeratotic variant
What does transient lingual papillitis appear as?
-Large red/yellow papilla
For symptomatic transient lingual papillitis what might help reduce the pain?
-Topical steroids
What are recurrent aphthous ulcerations aka?
-Recurrent aphthous stomatitis (canker sores)
Where do recurrent aphthous ulcers occur exclusively?
-Movable mucosa
What are the three clinical variations of Recurrent aphthous ulcers?
- Minor
- Major
- Herpetiform
When does RAU occur?
-Childhood
What is the most common form of RAU?
-Minor
T/F Pats with RAU minor typically have a prodrome
True
What does RAU minor appear as in size?
-Less than 1 cm
How fast does RAU minor heal?
-7-10 days spontaneously
Who does RAU major occur in?
-Adolescents
What does RAU major appear as in size?
1-3 cm
What type of RAU has the longest duration per episode?
-Major
How long does it take RAU to heal?
2-6 weeks
T/F RAU major may cause scarring
True
How many lesions per episode do you get in RAU Minor?
-1-5
How many lesions per episode do you get in RAU major?
1-10
What are the most commonly involved locations of RAU major?
- Labial mucosa
- Soft palate
- Tonsillar fauces
What is major aphthus uclers aka?
-Suttons disease
Who does RAU herpetiform occur in?
Adults
What type of RAU occurs in greatest numbers of lesions and recurrences?
-Herpetiform stomatitis
What is the size of herpetiform RAU?
1-3 mm
What is the healing time of herpetiform RAU?
7-10 days
Which type of RAU is scarring possible?
-Major
How many lesions are possible for RAU herpetiform?
-up to 100
What is a chronic recurrent immune mediated disease with oral aphthous like ulcerations, ocular inflammation, genital ulcers and skin lesions?
-Behcet’s syndrome
What is associated with Behcet’s syndrome?
- Ocular inflammation
- Genital ulcers
- Oral aphthous-like ulcers
- Joint pain
What is the treatment for Behcet’s syndrome?
-Systemic and topical steroids
What is a multisystem granulomatous disorder of unknown cause?
-Sarcoidosis
What organs are most commonly involved in sarcoidosis?
- Lungs
- Lymph nodes
- Skin
- Eyes
- Salivary glands
T/F Lymphoid tissue is involved in almost all cases of sarcoidosis
True
What pt is most likely to have sarcoidosis?
-African Americans
What are two different syndromes associated with sarcoidosis?
- Lofgren’s syndrome
- Heerfordt’s syndrome
If you have sarcoidosis on the skin what is it termed?
-Lupus pernio
If you have scattered, nonspecific, tender, red nodules on lower legs, what is that termed?
-Erythema nodosum
What is associated with Lofgren’s syndrome?
- Erythema nodosum
- Bilateral hilar lymphadenopathy
- Arthralgia (joint pain)
What is associated with Heerfordt’s syndrome?
- Parotid enlargement
- Inflammation of eye
- Facial paralysis
- Fever
- aka uveoparotid fever
What are the histological features of Sarcoidosis?
- Granulomatous inflammation
- Schaumann bodies
- Asteroid bodies
- Hamazaki-Wesenberg bodies
What is needed to diagnose sarcoidosis?
- Elevated serum angiotensin-converting enzyme levels
- Chest XRAY
- Kveim test
When only the lips are involved with orofacial granulomatosis what is that known as?
-Cheilitis granulomatosa
What is Melkersson-Rosenthal syndrome?
- Cheilitis granulomatosa
- Facial paralysis
- Fissured tongue
What does classic Wegner’s granulomatosis have associated with it?
- Necrotizing granulomatous lesions of respiratory tract,
- necrotizing glomerulonephritis
- Systemic vasculitis of small arteries and veins
What are the oral lesions are characteristic of wegner’s granulomatosis?
-Strawberry gingivitis
How do you diagnose Wegner’s granulomatosis?
-Indirect immunofluorescence detecs presence of antineutrophil cytoplasm antibodies (cytoplasmic)
If wegner’s granulomatosis goes untreated what is the prognosis?
-10% two year survival
