Chapter 14 lecture 2 Flashcards

1
Q

What is a diverse group of processes characterized by replacement of normal bone by fibrous tissue containing a mineralized product?

A

-Fibro-Osseous lesions

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2
Q

What are some examples of benign fibro-osseous lesions?

A
  • Fibrous dysplasia
  • Cemento-osseous dysplasia
  • Ossifying fibroma
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3
Q

What is characterized by replacement of normal bone by fibrous connective tissue intermixed with bone that is a sporadic condition resulting from a postzygotic mutation?

A

-Fibrous dysplasia

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4
Q

What is the chief radiographic feature of fibrous dysplasia?

A

-Fine ground glass opactification

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5
Q

What are the two syndromes found in the polyostotic fibrous dysplasia?

A
  • Jaffe-Lichtenstein syndrome

- McCune-Albright Syndrome

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6
Q

What is the most common type of fibrous dysplasia?

A

-Monostotic in the maxilla

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7
Q

When is monostotic fibrous dysplasia usually diagnosed?

A

-Teenage years

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8
Q

What is the most common feature of monostatic fibrous dysplasia?

A

-Slowly growing swelling of the affected area

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9
Q

What do you see in Jaffe-Lichtenstein syndrome?

A
  • Polyostotic fibrous dysplasia

- Cafe au lait spots (Coast of Maine)

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10
Q

What do you see in McCune-Albright syndrome?

A
  • Polyostotic fibrou dysplasia
  • Cafe au laite spots (Coast of maine)
  • Multiple endocrinopathies
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11
Q

Where does cemento-osseous dysplasia occur?

A

-Tooth bearing areas of the Jaw

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12
Q

What is the most common fibro-osseous lesion encountered in clinical practice?

A

-Cemento-Osseous dysplasia

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13
Q

What are the three types of cemento-osseous dysplasia?

A
  • Focal
  • Periapical
  • Florid
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14
Q

What does focal-Cemento-osseous dysplasia exhibit?

A

-Single sight of involvement

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15
Q

Where is the most common place of focal cemento-osseous dysplasia?

A

-Posterior mandible

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16
Q

Who do you see periapical cemento-osseous dysplasia in?

A

-Female African americans around 40

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17
Q

Where do you see periapical cemento-osseous dysplasia?

A

-Periapical region of the anterior mandible

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18
Q

What is florid cemento-osseous dysplasia?

A

-Multiple focal involvement not limited to the anterior mandible

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19
Q

Is cemento-osseous dysplasia symptomatic?

A

-No

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20
Q

Who do you see florid cemento-osseous dysplasia in?

A

-Female African Americans

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21
Q

What might extraction of a tooth in a person with florid COD lead to?

A

-Necrosis

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22
Q

What type of cemento-osseous dysplasia do you biopsy?

A

-Focal

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23
Q

What is an ossifying fibroma?

A

-True neoplasm with significant growth potential

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24
Q

What do early lesions of Cemento-osseous dysplasia appear as?

A

Radiolucent

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25
Q

What do middle lesions of cemento-osseous dysplasia appear as?

A

-Radiolucent with Radioopacitiy

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26
Q

What has large ossifying fibromas of the mandible demonstrate a characteristic downward bowing of the inferior cortex of the mandible?

A

-Ossifying fibroma

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27
Q

How do you distinguish between juvenile ossifying fibroma from an ossifying fibroma?

A
  • Age of patient
  • Most common sites of involvement
  • Clinical behavior
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28
Q

Where does juvenile ossifying fibromas occur more commonly?

A

-Maxilla

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29
Q

Who does juvenile ossifying fibromas occur more commonly in?

A

-Males

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30
Q

Where does ossifying fibromas occur more commonly?

A

-Mandible

31
Q

Who does ossifying fibromas occur more commonly in?

A

-Females

32
Q

What is an osteoma?

A

-Benign tumors of mature bone

33
Q

Where is an osteoma restricted to?

A

-Craniofacial skeleton

34
Q

Where does osteoma arise on?

A

-Surface of bone or within medullary bone

35
Q

T/F Osteomas exhibit continued growth

A

True

36
Q

What characterizes Gardner syndrome?

A
  • Clonic polyps
  • Skeletal abnormalities
  • Dental abnormalities
  • Epidermoid cysts
  • Dermoid tumors
  • Thyroid carcinoma
  • Pigmented lesions of the ocular fundus
37
Q

In Gardner syndrome what will bowel polyps transform into?

A

-Adenocarcinoma

38
Q

What skeletal abnormalities do you most commonly see in Gardner syndrome?

A

-Osteomas

39
Q

What dental abnormalities do you see in Gardner syndrome?

A
  • Supernumerary teeth
  • Impacted teeth
  • Odontomas
40
Q

What treatment do you need to do in Gardner syndrome?

A

-Prophylactic colectomy

41
Q

What are closely related benign bone tumors?

A
  • Osteoblastoma

- Osteoid Osteoma

42
Q

What does osteoid osteoma produce?

A

-Prostaglandins

43
Q

What is the pain relieved by in osteoid osteoma?

A

-Aspirin

44
Q

What are the size of osteoid osteomas?

A

-Smaller than 2 cm

45
Q

What are the size of osteoblastomas?

A

-Larger than 2 cm

46
Q

T/F Osteoblastomas are painful

A

True

47
Q

What type of pain do you see in osteoid osteoma?

A

-Nocturnal

48
Q

What is a cementoblastoma?

A

-Odontogenic neoplasm of cementoblasts

49
Q

Where do most cementoblastomas occur?

A

-Mandible in the molar/premolar region

50
Q

If you can see the root outline/PDL in the radioopacity will it be a cementoblastoma?

A

-No

51
Q

What is a chondroma?

A

-Benign tumor of cartilage

52
Q

T/F Synovial chondromatosis is a rare, benign , non neoplastic tumor

A

True

53
Q

Where does synovial chondromatosis most commonly affect?

A

-Large joints but can affect the TMJ

54
Q

What are some common features of synovial chondromatosis?

A
  • Swelling
  • Pain
  • Crepitus
  • Limitation of motion
55
Q

What do you see in an XRAY in someone with synovial chondromatosis?

A

-Loose bodies

56
Q

What is an osteosarcoma?

A

-Mesenchymal malignancy

57
Q

If you exclude hematopoietic neoplasma what is the most common type of malignancy to originate within bone?

A

-Osteosarcoma

58
Q

Whais the most common malignancy of bone?

A

-Metastatic disease

59
Q

Extragnathic osteosarcomas have a bimodal age distrubution, when does it occur?

A
  • 10-20 yrs most common

- After 50

60
Q

What is the most common place for osteosarcomas to arise in young pts?

A
  • Distal femur

- Proximal tibia

61
Q

When do ostosarcomas of the jaw occur?

A

-around age 33

62
Q

In an XRAY you see a sunburst appearance, what should you be thinking of?

A

-Osteosarcoma

63
Q

A triangular elevation of periosteum associated with osteosarcoma is termed what?

A

-Codman’s triangle

64
Q

Root resorption which is termed spiking resorption is associated with what?

A

-Osteosarcoma

65
Q

What is a Juxtacortical osteosarcoma aka?

A

-Peripheral osteosarcoma

66
Q

What is a chondrosarcoma?

A

-Malignant bone tumor of cartilage

67
Q

What is ewing sarcoma?

A

-Primary malignant tumor of bone

68
Q

What is the 3rd most common osseous neoplasm?

A

-Ewing sarcoma

69
Q

If you see the onionskin in an XRAY what are you thinking of?

A

-Ewing sarcoma

70
Q

What is the most common form of cancer involving bone?

A

-Metastatic tumor

71
Q

What are the most common origins of Gnathic mets?

A
  • Breast
  • Lung
  • Thyroid
  • Prostate
  • Kidney
72
Q

What is a numb-chin syndrome associated with?

A

-Metastatic tumor

73
Q

If you see the moth-eaten feature in an XRAY what are you thinking?

A

-Metastatic tumor