Key Phrases For Exam 3

Question 1

most common “tumor” of the oral cavity

Answer 1

fibroma

Question 2

McCune Albright Syndrome

Answer 2

Polyostotic Fibrous Dysplasia, with “coast of Maine” Cafe Au Lait spots AND multiple endocrinopathies (sexual precocity, pituitary adenoma, Hyperthyroidism)

Question 3

Most common cutaneous / skin lymphoma

Answer 3

Mycosis Fungoides (resembles a fungal infection, but it’s a T-cell lymphoma)

Question 4

Will have “Verocay bodies” on histo (indicating that it is the Antoni A variant)

Answer 4

Schwannoma (Neurilemoma)

Question 5

Letterer-Siwe disease

Answer 5

ACUTE disseminated histocytosis (a disseminated subtype of langerhans cell histiocytosis)

Question 6

The subtype of leukemia that is most common in kids

Answer 6

ALL - Acute LymphoBlastic Leukemia

Question 7

Most common malignant salivary gland neoplasm IN THE SUBMANDIBULAR GLAND SPECIFICALLY

Answer 7

Adenoid Cystic Carcinoma

Question 8

cotton wool or cotton roll appearance of bone

Answer 8

Paget’s disease of bone

Question 9

Lisch Nodules

Answer 9

AKA Iris Hamartomas, or basically little freckles in your iris (assoc. with NF1 - NeuroFibromatosis type 1)

Question 10

Most common cancer INVOLVING bone

Answer 10

Metastatic carcinoma, from another site.

Question 11

Most common Mesenchymal neoplasm overall. Biopsy floats in formalin.

Answer 11

Lipoma

Question 12

glossopyrosis, glossodynia, & tongue atropy/bald tongue all symptoms of:

Answer 12

Anemia

Question 13

Pseudoepitheliomatous hyperplasia (also S-100 test positive)

Answer 13

Granular Cell tumor (most often seen in dorsal tongue)

Remember Congenital Epulis is NOT S-100 positive and doesn’t show the PEH)

Question 14

Most common type of leukemia overall, & more often seen in adults

Answer 14

CLL - Chronic LymphoCytic Leukemia

Question 15

Histologic term for the clinical diagnosis of “epulis fissuratum”

Answer 15

IFH - Inflammatory Fibrous Hyperplasia, caused by flange of an ill fitting denture

Question 16

“punched out radiolucency” of bone, with teeth floating in air

Answer 16

langerhans cell histiocytosis

Question 17

What 2 syndromes are “coast of Maine” Cafe Au Lait spots seen in?

Answer 17

Jaffe-Lichtenstein and McCune Albright syndrome

Question 18

Jaffe-Lichtenstein Syndrome

Answer 18

Polyostotic Fibrous Dysplasia, with “coast of Maine” Cafe Au Lait Spots

Question 19

“Starry-Sky pattern” on histo

Answer 19

Burkitt’s lymphoma (remember this is most common in african kids, so picture african kids all looking up at the starry sky on the savannah)

Question 20

most common lymphoma of the oral cavity

Answer 20

Diffuse Large B Cell Lymphoma (a type of NON-hodgkin’s lymphoma)

Question 21

differential of 4 most common “bump on the gums”

Answer 21

Inflammatory Fibrous Hyperplasia
Pyogenic Granuloma
Peripheral Giant Cell Granuloma
Peripheral Ossifying Fibroma

Question 22

“loose bodies”, or radiographic appearance of “tonsilloliths in the TMJ area”,

Answer 22

Synovial chondromatosis

Question 23

“Sunburst appearance” on radiograph, and “spiking resorption” of roots

Answer 23

Osteosarcoma

Question 24

Often Blue-purple bump on the gums, may produce “cupping resorption” of underlying bone

Answer 24

Peripheral Giant Cell Granuloma

Question 25

6+ Cafe Au Lait macules with "coast of california'

Answer 25

NF1 - NeuroFibromatosis type 1

Question 26

Birbeck Granules

Answer 26

The rod shaped cytoplasmic structures that differentiate langerhans cells from other APC's (langerhans cell histiocytosis)

Question 27

Most common Fibro-osseous lesions seen in clinical practice

Answer 27

COD - Cemento-Osseous Dysplasia (3 types)

Question 28

Reed-sternberg cells

Answer 28

The neoplastic cells seen in Hodgkin's Lymphoma (though they only make up about 1-3% of cells in the lesion)

Question 29

high urinary levels of vanillylmandelic acid seen in:

Answer 29

Melanotic neuroectodermal tumor of infancy

Question 30

Bone tumor arising on the surface of bone

Answer 30

Osteoma

Question 31

most common salivary gland neoplasm

Answer 31

Pleomorphic adenoma (so obviously also the most common benign one too)

Question 32

Hand-Schuller Christian disease

Answer 32

CHRONIC disseminated histiocytosis (a disseminated subtype of langerhans cell histiocytosis)

Question 33

"Von Recklinghausen's disease of the skin"

Answer 33

NF1 - NeuroFibromatosis type 1

Question 34

Defect in collagen type 1 maturation, also most common type of INHERITED bone disease

Answer 34

Osteogenesis Imperfecta

Question 35

Most common tumor of infancy

Answer 35

Hemangioma

Question 36

"Philadelphia chromosome" involves translocation of what 2 chromosomes, and what disease?

Answer 36

chromosomes 9 & 22, seen in CML - Chronic Myeloid Leukemia

Question 37

Crowe's sign

Answer 37

Freckling in the axillary region (assoc. with NF1 - NeuroFibromatosis type 1)

Question 38

Bence Jones proteins

Answer 38

In Multiple Myeloma. These proteins will build up and overburden the kidneys, and make it out into the urine

Question 39

swelling and eversion of lower lip / "bubba gump" with red inflamed salivary duct openings

Answer 39

Cheilitis glandularis

Question 40

"blood soaked sponge" surgical appearance of bone lesion

Answer 40

Anuerysmal bone cyst

Question 41

Sicca Syndrome

Answer 41

Sjogren's syndrome with involvement of BOTH dry mouth and dry eyes

Question 42

Most common malignant salivary gland neoplasm

Answer 42

Mucoepidermoid carcinoma | ****except for in submandibular gland only then it's Adenoid Cystic Carcinoma!

Question 43

What syndrome is "coast of California" cafe au lait spots seen in?

Answer 43

Neurofibromatosis

Question 44

Sezary Syndrome

Answer 44

an aggressive, diffuse form of mycosis fungoides

Question 45

"pregnancy tumor" / Granuloma Gravidarum

Answer 45

Pyogenic Granuloma

Question 46

"frosted shower door" or "ground glass" opacification of bone

Answer 46

Fibrous Dysplasia (monostotic & polyostotic)

Question 47

neoplasm causing "downward bowing of the cortex of the mandible"

Answer 47

Ossifying Fibroma

Question 48

"frog eggs" or "tapioca pudding" of anterior 2/3 tongue most commonly

Answer 48

lymphangioma

Question 49

unilaterlal Port Wine Staining of the face / nevus flammeus

Answer 49

Seen with Sturge Weber Angiomatosis | though also seen in some other non-related disorders