Key Phrases For Exam 3 Flashcards
most common “tumor” of the oral cavity
fibroma
McCune Albright Syndrome
Polyostotic Fibrous Dysplasia, with “coast of Maine” Cafe Au Lait spots AND multiple endocrinopathies (sexual precocity, pituitary adenoma, Hyperthyroidism)
Most common cutaneous / skin lymphoma
Mycosis Fungoides (resembles a fungal infection, but it’s a T-cell lymphoma)
Will have “Verocay bodies” on histo (indicating that it is the Antoni A variant)
Schwannoma (Neurilemoma)
Letterer-Siwe disease
ACUTE disseminated histocytosis (a disseminated subtype of langerhans cell histiocytosis)
The subtype of leukemia that is most common in kids
ALL - Acute LymphoBlastic Leukemia
Most common malignant salivary gland neoplasm IN THE SUBMANDIBULAR GLAND SPECIFICALLY
Adenoid Cystic Carcinoma
cotton wool or cotton roll appearance of bone
Paget’s disease of bone
Lisch Nodules
AKA Iris Hamartomas, or basically little freckles in your iris (assoc. with NF1 - NeuroFibromatosis type 1)
Most common cancer INVOLVING bone
Metastatic carcinoma, from another site.
Most common Mesenchymal neoplasm overall. Biopsy floats in formalin.
Lipoma
glossopyrosis, glossodynia, & tongue atropy/bald tongue all symptoms of:
Anemia
Pseudoepitheliomatous hyperplasia (also S-100 test positive)
Granular Cell tumor (most often seen in dorsal tongue)
Remember Congenital Epulis is NOT S-100 positive and doesn’t show the PEH)
Most common type of leukemia overall, & more often seen in adults
CLL - Chronic LymphoCytic Leukemia
Histologic term for the clinical diagnosis of “epulis fissuratum”
IFH - Inflammatory Fibrous Hyperplasia, caused by flange of an ill fitting denture
“punched out radiolucency” of bone, with teeth floating in air
langerhans cell histiocytosis
What 2 syndromes are “coast of Maine” Cafe Au Lait spots seen in?
Jaffe-Lichtenstein and McCune Albright syndrome
Jaffe-Lichtenstein Syndrome
Polyostotic Fibrous Dysplasia, with “coast of Maine” Cafe Au Lait Spots
“Starry-Sky pattern” on histo
Burkitt’s lymphoma (remember this is most common in african kids, so picture african kids all looking up at the starry sky on the savannah)
most common lymphoma of the oral cavity
Diffuse Large B Cell Lymphoma (a type of NON-hodgkin’s lymphoma)
differential of 4 most common “bump on the gums”
Inflammatory Fibrous Hyperplasia
Pyogenic Granuloma
Peripheral Giant Cell Granuloma
Peripheral Ossifying Fibroma
“loose bodies”, or radiographic appearance of “tonsilloliths in the TMJ area”,
Synovial chondromatosis
“Sunburst appearance” on radiograph, and “spiking resorption” of roots
Osteosarcoma
Often Blue-purple bump on the gums, may produce “cupping resorption” of underlying bone
Peripheral Giant Cell Granuloma
6+ Cafe Au Lait macules with “coast of california’
NF1 - NeuroFibromatosis type 1
Birbeck Granules
The rod shaped cytoplasmic structures that differentiate langerhans cells from other APC’s (langerhans cell histiocytosis)
Most common Fibro-osseous lesions seen in clinical practice
COD - Cemento-Osseous Dysplasia (3 types)
Reed-sternberg cells
The neoplastic cells seen in Hodgkin’s Lymphoma (though they only make up about 1-3% of cells in the lesion)
high urinary levels of vanillylmandelic acid seen in:
Melanotic neuroectodermal tumor of infancy
Bone tumor arising on the surface of bone
Osteoma
most common salivary gland neoplasm
Pleomorphic adenoma (so obviously also the most common benign one too)
Hand-Schuller Christian disease
CHRONIC disseminated histiocytosis (a disseminated subtype of langerhans cell histiocytosis)
“Von Recklinghausen’s disease of the skin”
NF1 - NeuroFibromatosis type 1
Defect in collagen type 1 maturation, also most common type of INHERITED bone disease
Osteogenesis Imperfecta
Most common tumor of infancy
Hemangioma
“Philadelphia chromosome” involves translocation of what 2 chromosomes, and what disease?
chromosomes 9 & 22, seen in CML - Chronic Myeloid Leukemia
Crowe’s sign
Freckling in the axillary region (assoc. with NF1 - NeuroFibromatosis type 1)
Bence Jones proteins
In Multiple Myeloma. These proteins will build up and overburden the kidneys, and make it out into the urine
swelling and eversion of lower lip / “bubba gump” with red inflamed salivary duct openings
Cheilitis glandularis
“blood soaked sponge” surgical appearance of bone lesion
Anuerysmal bone cyst
Sicca Syndrome
Sjogren’s syndrome with involvement of BOTH dry mouth and dry eyes
Most common malignant salivary gland neoplasm
Mucoepidermoid carcinoma
**except for in submandibular gland only then it’s Adenoid Cystic Carcinoma!
What syndrome is “coast of California” cafe au lait spots seen in?
Neurofibromatosis
Sezary Syndrome
an aggressive, diffuse form of mycosis fungoides
“pregnancy tumor” / Granuloma Gravidarum
Pyogenic Granuloma
“frosted shower door” or “ground glass” opacification of bone
Fibrous Dysplasia (monostotic & polyostotic)
neoplasm causing “downward bowing of the cortex of the mandible”
Ossifying Fibroma
“frog eggs” or “tapioca pudding” of anterior 2/3 tongue most commonly
lymphangioma
unilaterlal Port Wine Staining of the face / nevus flammeus
Seen with Sturge Weber Angiomatosis
though also seen in some other non-related disorders
