Chapter 12 lecture 2 soft tissue tumors Flashcards

1
Q

What is a true neoplasm exhibiting fibroblastic and histiocytic differentiation?

A

-Fibrous histiocytoma

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2
Q

Where does fibrous histiocytoma most commonly occur?

A

-Skin

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3
Q

What is a fibrous histiocytoma on the skin known as?

A

-Dermatofibroma

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4
Q

What represents the oral counterpart of cutaneous focal mucinosis?

A

-Oral focal mucinosis

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5
Q

What does oral focal mucinosis result from?

A

-Overproduction of hyaluronic acid by fibroblasts

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6
Q

Who does oral focal mucinosis most commonly occur in?

A

-Young females

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7
Q

Where does oral focal mucinosis tend to occur?

A
  • gingiva 2/3

- hard palate 1/3

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8
Q

What is not a true granuloma but is a reactive lesion to local irritation or trauma?

A

-Pyogenic granuloma

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9
Q

Where is the location that you can see a pyogenic granuloma?

A
  • Gingiva
  • Lips
  • Tongue
  • Buccal mucosa
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10
Q

Who is pyogenic granulomas most commonly found in?

A
  • Children

- Young adults

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11
Q

What is pyogenic granuloma also known as?

A
  • Pregnancy tumor

- Granuloma gravidarum

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12
Q

When you excise a pyogenic granuloma how far should you go?

A

-The excision should extend to periosteum

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13
Q

Besides pyogenic granuloma what is another granuloma that is a reactive lesion caused by local irritation or trauma?

A

-Peripheral Giant Cell Granuloma

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14
Q

Where does the peripheral Giant cell granuloma occur exclusively?

A

-On the gingiva or edentulous alveolar ridge

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15
Q

How do you differentiate a Pyogenic granuloma from a PGCG?

A

-The PGCG is more blue or purple compared to the bright red of a PG

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16
Q

What is the treatment for a pyogenic giant cell granuloma?

A

-local surgical excision down to underlying bone

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17
Q

What can pyogenic giant cell granulomas due to the bone?

A

-Produce a cupping resorption of the underlying alveolar bone

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18
Q

What are four differentials that you use if you see a bump on the gums?

A
  • IFH (inflammatory fibrous hyperplasia)
  • Pyogenic granuloma (vasculature)
  • Pyogenic giant cell granuloma (giant cells)
  • Peripheral Ossifying Fibroma (bone)
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19
Q

Where does a peripheral ossifying Fibroma occur exclusively?

A

-Gingiva

20
Q

Where does a peripheral ossifying fibroma originate from?

A

-Dental papilla

21
Q

Where do 50% of peripheral ossifying fibromas occur?

A

-Incisor cuspid region

22
Q

What is a benign tumor of fat?

A

-Lipoma

23
Q

What is the most common mesenchymal neoplasm?

A

-Lipoma

24
Q

T/F A Peripheral ossifying fibroma can occur on the mucosa

A

False

-It can only occur on the gingiva

25
Q

What is the average age of a person with a peripheral ossifying fibroma?

A

-15

26
Q

What does a peripheral ossifying fibroma appear as clinically most of the time?

A

-Pale bump on the gums

27
Q

What does a lipoma do in formalin?

A

-Float

28
Q

What is a neuroma?

A

-Benign tumor of nerve tissue

29
Q

What can a neuroma be?

A
  • A traumatic neuroma

- Palisaded encapsulated neuroma

30
Q

What is the most common area of a neuroma?

A

-Mental foramen area

31
Q

What is a palisaded encapsulated neuroma also known as?

A

-Solitary circumscribed neuroma

32
Q

What is a benign neural neoplasm of Schwann cell origin?

A

-Schwannoma (Neurilemoma)

33
Q

What are characteristics of a Shwannoma?

A
  • Slow-growing
  • Encapsulated
  • Associated with the nerve trung
34
Q

Who do Shwannomas most commonly occur in?

A

-Middle-aged adults

35
Q

What is the most common location for an oral Shwanoma?

A

-Tongue

36
Q

What are the histopathologic feature of a Shwannoma?

A
  • Antoni A

- Antoni B

37
Q

What do Antoni A bodies have associated with them?

A
  • Verocay bodies
38
Q

What do Antoni B bodies have with them?

A

-Everything that is not is not Antoni A

39
Q

What is the most common type of peripheral nerve neoplasm?

A

-Neurofibroma

40
Q

What can arise as solitary tumors or be a component of neurofibromatosis?

A

-Neurofibroma

41
Q

What is neurofibromatosis type I also known as?

A

-Recklinghausen’s disease of the skin

42
Q

What is a pathognomonic of NF1?

A

-Plexiform varient

43
Q

What are the diagnostic criteria of NF1? (need 2 or more)

A
  • Six or more cafe au lait macules
  • Two or more Neurofibromas or one plexiform Neurofibromas
  • Freckling in the axillary region (Crowe’s sign)
  • Optic glioma
  • Two or more iris hamartomas (Lisch nodules)
  • Osseous lesion such as sphenoid dysplasia
  • First degree relative with NF1
44
Q

What is crowe’s sign?

A

-Freckling in the axillary region

45
Q

What does a plexiform neurofibromatotis feel like?

A

Bag of worms

46
Q

What are the oral manifestations that can be seen with NF1?

A
  • Enlargment of the fungiform papilla
  • Intraoral neurofibromas
  • Enlargment of the mandibular foramen or canal
47
Q

What is a lisch nodule?

A

-Two or more iris hamartomas