Chapter 12 lecture 2 soft tissue tumors Flashcards
What is a true neoplasm exhibiting fibroblastic and histiocytic differentiation?
-Fibrous histiocytoma
Where does fibrous histiocytoma most commonly occur?
-Skin
What is a fibrous histiocytoma on the skin known as?
-Dermatofibroma
What represents the oral counterpart of cutaneous focal mucinosis?
-Oral focal mucinosis
What does oral focal mucinosis result from?
-Overproduction of hyaluronic acid by fibroblasts
Who does oral focal mucinosis most commonly occur in?
-Young females
Where does oral focal mucinosis tend to occur?
- gingiva 2/3
- hard palate 1/3
What is not a true granuloma but is a reactive lesion to local irritation or trauma?
-Pyogenic granuloma
Where is the location that you can see a pyogenic granuloma?
- Gingiva
- Lips
- Tongue
- Buccal mucosa
Who is pyogenic granulomas most commonly found in?
- Children
- Young adults
What is pyogenic granuloma also known as?
- Pregnancy tumor
- Granuloma gravidarum
When you excise a pyogenic granuloma how far should you go?
-The excision should extend to periosteum
Besides pyogenic granuloma what is another granuloma that is a reactive lesion caused by local irritation or trauma?
-Peripheral Giant Cell Granuloma
Where does the peripheral Giant cell granuloma occur exclusively?
-On the gingiva or edentulous alveolar ridge
How do you differentiate a Pyogenic granuloma from a PGCG?
-The PGCG is more blue or purple compared to the bright red of a PG
What is the treatment for a pyogenic giant cell granuloma?
-local surgical excision down to underlying bone
What can pyogenic giant cell granulomas due to the bone?
-Produce a cupping resorption of the underlying alveolar bone
What are four differentials that you use if you see a bump on the gums?
- IFH (inflammatory fibrous hyperplasia)
- Pyogenic granuloma (vasculature)
- Pyogenic giant cell granuloma (giant cells)
- Peripheral Ossifying Fibroma (bone)
Where does a peripheral ossifying Fibroma occur exclusively?
-Gingiva
Where does a peripheral ossifying fibroma originate from?
-Dental papilla
Where do 50% of peripheral ossifying fibromas occur?
-Incisor cuspid region
What is a benign tumor of fat?
-Lipoma
What is the most common mesenchymal neoplasm?
-Lipoma
T/F A Peripheral ossifying fibroma can occur on the mucosa
False
-It can only occur on the gingiva
What is the average age of a person with a peripheral ossifying fibroma?
-15
What does a peripheral ossifying fibroma appear as clinically most of the time?
-Pale bump on the gums
What does a lipoma do in formalin?
-Float
What is a neuroma?
-Benign tumor of nerve tissue
What can a neuroma be?
- A traumatic neuroma
- Palisaded encapsulated neuroma
What is the most common area of a neuroma?
-Mental foramen area
What is a palisaded encapsulated neuroma also known as?
-Solitary circumscribed neuroma
What is a benign neural neoplasm of Schwann cell origin?
-Schwannoma (Neurilemoma)
What are characteristics of a Shwannoma?
- Slow-growing
- Encapsulated
- Associated with the nerve trung
Who do Shwannomas most commonly occur in?
-Middle-aged adults
What is the most common location for an oral Shwanoma?
-Tongue
What are the histopathologic feature of a Shwannoma?
- Antoni A
- Antoni B
What do Antoni A bodies have associated with them?
- Verocay bodies
What do Antoni B bodies have with them?
-Everything that is not is not Antoni A
What is the most common type of peripheral nerve neoplasm?
-Neurofibroma
What can arise as solitary tumors or be a component of neurofibromatosis?
-Neurofibroma
What is neurofibromatosis type I also known as?
-Recklinghausen’s disease of the skin
What is a pathognomonic of NF1?
-Plexiform varient
What are the diagnostic criteria of NF1? (need 2 or more)
- Six or more cafe au lait macules
- Two or more Neurofibromas or one plexiform Neurofibromas
- Freckling in the axillary region (Crowe’s sign)
- Optic glioma
- Two or more iris hamartomas (Lisch nodules)
- Osseous lesion such as sphenoid dysplasia
- First degree relative with NF1
What is crowe’s sign?
-Freckling in the axillary region
What does a plexiform neurofibromatotis feel like?
Bag of worms
What are the oral manifestations that can be seen with NF1?
- Enlargment of the fungiform papilla
- Intraoral neurofibromas
- Enlargment of the mandibular foramen or canal
What is a lisch nodule?
-Two or more iris hamartomas
