Developmental Defects TEST #1 Flashcards
What forms the upper lip?
-Medial nasal processes merging with each other as well as the maxillary processes
What forms the primary palate?
-Merger of the medial nasal process
What forms the secondary palate?
-Maxillary processes
What is cleft lip?
-Defective fusion of the medial nasal process with the maxillary processes
T/F Most cases of cleft lift are bilateral
False
-Most are unilateral
What is the treatment of cleft LIP?
-Rule of 10s (10 weeks, 10 lbs, 10% HM)
What causes cleft palate?
-Failure of the palatal shelves to fuse
When thinking of CL and CP what is the most common and least common in developmental cases?
- CL and CP are most common
- CP (30%)
- CL (25%)
What is the most common CL and CP in syndromic cases?
-Cleft Palate Only
What is the most common syndromic orofacial cleft ?
-Vander Woude Syndrome
What do you see with Pierre Robin sequence?
- CP
- Mandibular micrognathia
- Glossoptosis
What causes a lateral facial cleft?
-Failure of fusion of maxillary and mandibular processes
In what ethnicity are you most likely to see orofacial clefting?
- Native Americans
- Asians
- Caucasians
- African Americans
What is a submucous palatal cleft?
-Minimal appearance of a cleft palate
What is a minimal manifestation of cleft palate?
-Bifid uvula
What syndrome are paramedian pits associated with?
-Van der Woude syndrome
What do you find in van der woude syndrome?
- Paramedian lip pits
- Cl + CP
- Autosomal Dominant
What is involved in Ascher syndrome?
- Double lip
- Blepharochalasis
- Nontoxic thyroid enlargement
What syndrome has paramedian lip pits, CL + CP, and Autosomal dominant?
-Van der woude syndrome
What syndrome presents with Double lip, blepharochalasis, nontoxic thyroid enlargement?
-Ascher syndrome
Where does double lip occur more commonly?
-upper lip
What is a fordyce granules?
-Ectopic sebaceous glands
Where is the most common location of fordyce granules?
-Buccal mucosa
What population of of people to fordyce granules occur most commonly in?
-Adults
What do fordyce granules clinically appear as?
–Yellow or yellow-white papular lesions