Chapter 6 Fungal and Protozoal diseases Flashcards

1
Q

What is the most common oral fungal infection in humans?

A

-Candidiasis

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2
Q

What bug causes candidiasis?

A

-Candida albicans

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3
Q

What are the two forms of candidiasis?

A
  • Yeast

- Hyphal

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4
Q

Which form of candidiasis is innocuous?

A

-Yeast

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5
Q

What form of candidiasis invades the host tissue?

A

-Hyphal

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6
Q

What are four clinical patterns of candidiasis?

A
  • Pseudomembranous
  • Erythematous
  • Chronic hyperplastic
  • Mucocutaneous
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7
Q

What is the only form of candidiasis that doesn’t rub off?

A

-Chronic hyperplastic

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8
Q

What is the best recognized form of candidiasis?

A

-Pseudomembranous

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9
Q

Can you wipe off candidiasis?

A

Yes

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10
Q

What are some symptoms of candidiasis?

A
  • Mild burning

- Mild unpleasant taste

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11
Q

What might initiate candidiasis?

A
  • Antibiotics
  • Immunocompromised
  • Asthma inhalers
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12
Q

With Erythematous candidiasis is there a major white component?

A

-No

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13
Q

What is the most common form of candidiasis?

A

-Erythematous

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14
Q

What are the clinical presentations of erythematous candidiasis?

A
  • Median rhomboid glossitis
  • Chronic multifocal candidiasis
  • angular chelitis
  • Denture stomatitis
  • Acute atrophic candidiasis
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15
Q

What is median rhomboid glossitis AKA?

A

-Central papillary atrophy

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16
Q

Where do you see median rhomboid glossitis?

A

-Posterior dorsal tongue anterior to circumvallate papilla

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17
Q

What is chronic multifocal candidiasis?

A

-Median rhomboid glossitis + signs of infection at other sites

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18
Q

If a patient and angular chelitis and median rhomboid glossitis what can you diagnose them with?

A

-Chronic multifocal candidiasis

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19
Q

What can be a component of chronic multifocal, but usually occurs alone and is accentuated at the corners of the mouth where saliva can pool?

A

-Angular chelitis

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20
Q

What is the clinical pattern termed for angular cheilitis?

A

-Cheilocandidiasis (due to chronic lip licking)

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21
Q

Where is denture stomatitis seen?

A

-Denture-bearing areas of a maxillary removable denture

22
Q

What type of erythematous candidiasis follows a course of broad spectrum antibiotic treatments?

A

-Acute atrophic candidiasis

23
Q

What is the least common form of candidiasis?

A

-Chronic hyperplastic

24
Q

How do you get mucocutaneous candidiasis?

A
  • Iron-deficiency anemia
  • APECED (autoimmune syndrome)
  • Endocrine candidiasis syndrome
25
What are three drugs used to treat candidiasis?
- Nystatin - Amphotericin B - Imidazole agents
26
What is the most common systemic fungal infection in the US?
-Histoplasmosis
27
What bug causes Histoplasmosis?
-Histoplasma capsulatum
28
Where are the endemic areas of the US to get histoplasmosis?
- Ohio | - Mississippi River Valley
29
If a person has a painful ulcer that looks like a chancre what could it be?
-Histoplasmosis
30
Why do you find histoplasmosis in Ohio and Mississippi River Valley?
-Found with bat poop or bird pop
31
What bug causes blastomycosis?
-Blastomyces dermatitidis
32
Where do you find blastomycosis?
-Eastern areas of the US and into Canada
33
What differentiates blastomycosis from other cancers?
-Histology of psudoepitheliaomatous hyperplasia
34
What does Paracoccidioides brasiliensis cause?
-Paracoccidiodomycosis
35
What animal carries paracoccidiodomycosis?
-Nine-banded armadillo
36
Candida is the hyphal form that is infectious, most other fungal infections what is the infectious form?
-Spore (yeast)
37
Who do you find paracoccidiomycosis more commonly in and why?
-Men because female hormones protect them.
38
What does paracoccidiomycosis appear as in a histology slide?
-Mariners wheel (spore form)
39
What is Coccidiomycosis AKA?
-San Joaquin Valley Fever
40
What causes coccidiomycosis?
-Coccidioides immitis
41
What are the endemic areas of coccidiomycosis?
- Southwestern US | - Mexico
42
If you have erythema nodosum that affects the legs and is characterized by multiple painful inflammatory nodules and this reaction is occurring in conjunction with coccidiomycosis what is that termed?
-Valley fever
43
What causes cryptococcosis?
-Cryptococcus neoformans
44
What is unique to cryptococcosis?
-A Mucopolysaccharide capsule that protects it from host defense
45
Where do you get cryptococcosis?
-Pigeon poop
46
Where do you get Coccidiomycosis?
-Decaying/dead animals
47
Where do you get Zygomycosis?
-Decaying organic material
48
What population of people get zygomycosis?
-Diabetics
49
What form of mucormycosis or zygomycosis is important to health care provider?
-Rhinocerebral form (The one that causes problems)
50
What does zygomycosis appear as clinically?
-Black and necrotic
51
What is the second in frequency to candidiasis for a fungal infection?
-Aspergillosis
52
If an aspergillosis mass undergoes dystrophic calcification what can be seen via a radiograph?
-Antrolith