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CNS I > NeuroImaging > Flashcards

NeuroImaging Flashcards

Be able to describe how neuroimaging technologies (specifically MRI, PET & CAT) work. Be able to list benefits and drawbacks of each technology, such as invasiveness and resolution. Be able to describe consistent neuroimaging findings for psychiatric and neurological disorders.

1
Q

shows up brightest in T1

A

solid tissues, such as WM, Bone, Fat, GM

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2
Q

shows up brightest in T2

A

liquids, such as CSF

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3
Q

dye useful to distinguish old lesions from new lesions in MRI

A

gadolinium

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4
Q

why is gadolinium used to check for new lesions in MRI

A

does not cross blood brain barrier, so will be extruded in new bleeding lesions

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5
Q

advantages of FLAIR MR imaging

A

T2 image that suppresses CSF, can see lesions close to ventricles

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6
Q

lesion in T1 view of MS

A

hypointense lesions in Corpus callosum

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7
Q

lesion in T2 view of MS

A

hyperintense WM plaques

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8
Q

lesion in FLAIR view of MS

A

hyperintensites

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9
Q

imaging that can show white matter tracts

A

DTI

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10
Q

advantages of CT over MRI

A

cheaper, more widely available,can be used with metal in pt

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11
Q

disadvantages of CT

A

uses ionizing radiation

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12
Q

advantages of MR over CT

A

better spatial resolution, non ionizing radiation

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13
Q

way PET

A

radioactive glucose-type molecule is not metabolized, and sticks to the cell

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14
Q

PET shows

A

baseline metabolism

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15
Q

PET good for showing

A

cancer and epileptic loci

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16
Q

imaging findings characteristic of dementia

A

global reduction in gray matter volume

17
Q

imaging findings characteristic of schizophrenia

A

no consistant abnormality, but increase in number of common abnormalities. Possibly enlarged ventricles

18
Q

imaging findings characteristic of depression

A

POSSIBLE increase in amygdala

19
Q

PET finding in depression

A

amygdala hypometabolism

20
Q

FMRI finding in depression

A

subgenual cingulate hypo-response
inferior frintal hypo-response to positive images
amydgala hyper response to negative images

21
Q

fMRI finding in PTSD

A

hyper-resoponse in right frontal and amygdala to threatening stimuli, reduced benzo binding, smaller hippocampal volumes

22
Q

PET finding in OCD

A

hyper-metabolism of OFC, cingulate, caudate

23
Q

fMRI finding in OCD

A

hyper-response in OFC, cingulate, and caudate to conflict tasks

24
Q

fMRI imaging findings in schizophrenia

A

decreased DLPFC activity during executive function tasks, elevated auditory cortex activity with auditory hallucinations

CNS I (36 decks)

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