Depression Flashcards
At the end of the learning the students will be able to: 1. List the diagnostic criteria for Major Depression including the two essential symptoms and time course and be able to identify the diagnosis in a vignette 2. State changes in sleep architecture seen in Major Depression 3. Compare and contrast normal grief, bereavement and major depression 4. List medical conditions and medications that are associated with depression and/or may produce symptoms consistent with depression 5. Des
“mood” is (internal/external)
internal
“affect” is (internal/external)
external
depression ranks ___ in the disablng disease hierechy
3rd
gender differences in adult MDD
more females than males
age group with less cumlative depression
60+
age of onset of MDD
20-40
6 frequent comorbidies (non psych) in MDD
heart disease, cancer, stroke, DM, HIV, parkinson’s
risk factors for suicide
male, over age 45/80, caucasian, living alone, single, marital status, previous attempt, chronic pain, illness, psyctic sx, unemployed
NT involved in MDD
NE, dopamine, serotonin
sleep issues in MDD
loss of deep sleep, increased nocturnal arousals, reduced REM latency, reduced REM density, reduced total sleep time
brain regions implicated in MDD
PFC, ACC, hippocampus, amygdala,
dysthymia vs MDD
dysthymia is longer term, less intense depression (for 2 years)
sx of atypical depression
weight gain, increased sleep, heaviness in arms/legs
dx criteria of derpression (number of sx and time)
5 or more sx for at least 2 weeks
sx of depression
depressed mood anhedonia sleep changes change in appetite/weight fatigue change in psycomotor activity feelings of guilt, worthlessness, hopelessness difficulty thinking and concentrating thoughts of death/sucidal idealation
