Bipolar Flashcards

• Describe a manic episode and differentiate it from hypomania or a primary psychotic episode • Differentiate between Bipolar I, Bipolar II and Cyclothymia • List common medications, medical conditions and environmental changes associated with mania

1
Q

age of onset in bipolar

A

20s

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2
Q

more severe bipolar (1/2)

A

2

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3
Q

prevalance of bipolar

A

1% lifetime prevalence

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4
Q

gender distribution in biolar

A

equal in I, more females in II

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5
Q

define hypomania

A

manic sx without psychotic sx

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6
Q

predictor of poor outcome in bipolar

A

psychotic mania

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7
Q

worsens the course of Bipolar

A

substance abuse

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8
Q

causes of mania after age 40

A

drugs, steroids, brain trauma, HIV, stroke, MS, epilepsy, tumor

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9
Q

precipitants for mania (7)

A

post-partum state, sleep deprivation, dopamine agonists, antidepressents, stroke/brain injury, jet lag, severe stress

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10
Q

hypomaniac pts are diagnosed with what type of bipolar

A

II

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11
Q

do pts know they are having a manic episode?

A

no, usually the behaviour is brought to their attention

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12
Q

rapid cycling definition

A

4 or more mood episodes a year

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13
Q

define dysphoric mania

A

depression and mania smultaniously

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14
Q

more common: depression or mania

A

depression

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15
Q

more likely to be depressed: bipolar 1 or 2

A

2

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16
Q

more likely to be asymptomatic at any given time, 1 or 2

A

1

17
Q

possible first sign of bipolar in teens

A

atypical depression

18
Q

may result from Li+ use

A

hypothyroidism

19
Q

can mimic depression

A

hypothyroidism

20
Q

risk of antidepressents in bipolar

A

can bring about manic episode

21
Q

definition of cyclothymia

A

2 years of hypomania and numerous periods of depressive sx that do not meet criteria for major depression

22
Q

chance of a bipolar pt having substance addiction

A

50%

23
Q

manic sx

A

inflated self esteem, decreased need for sleep, distractability, rapid speech, racing thoughts, increased goal directed behavior, excessive involvement in pleasurable activites

24
Q

acroym for manic sx

A

DIGFAST

25
Q

DIGFAST

A
distractable
increased activity
grandiosity
flight of ideas (racing thoughts)
activites that are dangerous or hypersexuality
sleep decreased
talkative speech
26
Q

definition of bipolar 1

A

manic episode, with or without episode of major depression

27
Q

definition of bipolar 2

A

major depression and hypomania

28
Q

dx criteria of bipolar 1

A

one manic episode (because 90% are going to have a depressive episode at some point(

29
Q

dx criteria of bipolar 2

A

hypomania and an episode of major depression

30
Q

distinguishes schizophrenia from bipolar

A

schizophrenia thoughts are mopre fragmented and bizzare with less intense affect

31
Q

areas in the brain effected by bipolar

A

PFC, Ventrat tegmental area, periaqueductal grey matter, basal ganglia

32
Q

define kindling in bipolar

A

idea that each episode makes it easier to have a subsequent episode

33
Q

3 bipolar classic mood stabilizers

A

lithium, valproic acid, carbamazepine

34
Q

6 2nd gen mood stabilizers

A

aripirazole, quetiapine, risperidone, ziprasidone, olanzapine

35
Q

drug combo for bipolar depression

A

fluoxetine-olanzaoine

36
Q

serious condition that lamotrigrine can cause

A

steven-johnson syndrome

37
Q

appoved for maintaince in bipolar

A

lamotrigine