encephalitis Flashcards
Diagnose viral encephalitis based on history, clinical presentation, and lab findings. Differentiate Eastern equine, Western equine, West Nile, St. Louis, California, and Japan encephalitis viruses. Diagnose hanta virus infection based on history, clinical presentation, and lab findings. Identify three viruses that cause hemorrhagic disease. Diagnose lymphocytic choriomeningitis based on history, clinical presentation, and lab findings
virus causing eastern equine E
togavirus
virus causing venezualan equine E
togavirus
virus causing westen equine E
togavirus
virus causing rubella virus
rubivorus
morphology of togavirus
enveloped, RNA,
virus causing yellow fever
flaviviridae
virus casuing dengue
flaviviridae
virus causing st louis/japanese/west nile E
flaviviridae
virus causing california/La crosse E
bunyaviridae
main difference in tranmission between buyaviridae and other arboviruses
can be transmitted from adults to eggs (transovarially)
type of virus causing colorado tick fever
orbivirus
sx of colorado tick fever
acute onset of fever, chills, headache, severe back and leg pain
main resivoir of colorado tick fever
ground squirrel
early onsex sx of arbovirus infection
nausea, headache, fever, muscle ache, malaise and leukopenia
encephalitis sx
headache, insomnia, letharg, ataxia, tremors, convulsions and coma
resiviors for arbovirus encephalitis viruses
birds and wild rodents
highest fatality encephalitis
eastern equine
high fatality flaviridae encephalitis
St Louis
Encephalitis with a horse resivior
VEE
family of Encephalitis infecting kids
toga/bunyaviridae
causes severe necrosis of CNS and viscera
EEE
encchepalitis confined to eastern US
EEE
leading cause of epidemic encephalitis
St Louis
type of virus causing STL E
flavivirus
Encephalitis endemic to upper midwest
california/LaCrosse
Enchephalitis causing fever, convulsions, drowsiness, and neurologic signs
CEV/LEV
cause of CEV/LEV
bunyavirus
cause of VEE
togavirus
cause of west nile
flavivirus
clincial signs of west nile
fever, rash, and headache
epidemic enphepalitis found in every state
WNE
99% of ____ infections are asymtomatic
WNE
early way to differentiate arbovirus from herpes encephalitis
Hx of outdoor travel and travel to endemic areas. Lab - IgM in CSF/RT-PCR in blood
______ production can triggger adaptive immune response to endemic encephalitis
interferon
antivirus in all suspected encephalitis
acyclovir
sx of dengue
fever, myalgia, anorexia, asthenia, maculopapular or petechial rash
severe form of dengue
dengue hemorrhagic fever
dengue hemorrhagic fever found more often in what population
otherwise healthy kids
possible mechanism for dengue hemorrhagic fever
pre-existing antibody to virus enhances binding and uptake of flaviiviruses to macrophages
virus causing dengue
flaviviridae
are dengue mosquitos that vector dengue present in US
yes
areas reporting sporadic dengue cases
texas and florida
major endemic areas of yellow fever
S America and Africa
systemic disease resulting in jaudince from liver involvment
yellow fever
two phase mosquito bourne virus
yellow fever
sx of phase I yellow fever
flu like sx, n/v
sx of phase ii yellow fever
jaundice, GI involvement, DIC and shock
urban yellow fever spread my man-mosquito-man
urban
jungle yellow fever spread by
mosquito-monkey-mosquito-man
type if mosquito carrying yellow fever
aedes aegypti
granular/sandy looking viruses
arenaviruses
type of virus passed from rodents to humans
arenaviruses
major arenavirus in the US
lymphatic choriomeningitis
clinical manifestation of lypmoocytic choriomenigitis
viral pneumibitis or meningitis
virus that causes hemorrhagic fevers 92)
arenavirus and hantavirus
3 arenavirus hemorrhagic fevers
lassa, Junin and machupo
junin and machupo endemic to
South America
sx of hantavirus
flu like sx, pulmonary edema leading to respiratory failure