encephalitis Flashcards

Diagnose viral encephalitis based on history, clinical presentation, and lab findings. Differentiate Eastern equine, Western equine, West Nile, St. Louis, California, and Japan encephalitis viruses. Diagnose hanta virus infection based on history, clinical presentation, and lab findings. Identify three viruses that cause hemorrhagic disease. Diagnose lymphocytic choriomeningitis based on history, clinical presentation, and lab findings

1
Q

virus causing eastern equine E

A

togavirus

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2
Q

virus causing venezualan equine E

A

togavirus

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3
Q

virus causing westen equine E

A

togavirus

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4
Q

virus causing rubella virus

A

rubivorus

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5
Q

morphology of togavirus

A

enveloped, RNA,

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6
Q

virus causing yellow fever

A

flaviviridae

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7
Q

virus casuing dengue

A

flaviviridae

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8
Q

virus causing st louis/japanese/west nile E

A

flaviviridae

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9
Q

virus causing california/La crosse E

A

bunyaviridae

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10
Q

main difference in tranmission between buyaviridae and other arboviruses

A

can be transmitted from adults to eggs (transovarially)

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11
Q

type of virus causing colorado tick fever

A

orbivirus

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12
Q

sx of colorado tick fever

A

acute onset of fever, chills, headache, severe back and leg pain

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13
Q

main resivoir of colorado tick fever

A

ground squirrel

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14
Q

early onsex sx of arbovirus infection

A

nausea, headache, fever, muscle ache, malaise and leukopenia

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15
Q

encephalitis sx

A

headache, insomnia, letharg, ataxia, tremors, convulsions and coma

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16
Q

resiviors for arbovirus encephalitis viruses

A

birds and wild rodents

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17
Q

highest fatality encephalitis

A

eastern equine

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18
Q

high fatality flaviridae encephalitis

A

St Louis

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19
Q

Encephalitis with a horse resivior

A

VEE

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20
Q

family of Encephalitis infecting kids

A

toga/bunyaviridae

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21
Q

causes severe necrosis of CNS and viscera

A

EEE

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22
Q

encchepalitis confined to eastern US

A

EEE

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23
Q

leading cause of epidemic encephalitis

A

St Louis

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24
Q

type of virus causing STL E

A

flavivirus

25
Q

Encephalitis endemic to upper midwest

A

california/LaCrosse

26
Q

Enchephalitis causing fever, convulsions, drowsiness, and neurologic signs

A

CEV/LEV

27
Q

cause of CEV/LEV

A

bunyavirus

28
Q

cause of VEE

A

togavirus

29
Q

cause of west nile

A

flavivirus

30
Q

clincial signs of west nile

A

fever, rash, and headache

31
Q

epidemic enphepalitis found in every state

A

WNE

32
Q

99% of ____ infections are asymtomatic

A

WNE

33
Q

early way to differentiate arbovirus from herpes encephalitis

A

Hx of outdoor travel and travel to endemic areas. Lab - IgM in CSF/RT-PCR in blood

34
Q

______ production can triggger adaptive immune response to endemic encephalitis

A

interferon

35
Q

antivirus in all suspected encephalitis

A

acyclovir

36
Q

sx of dengue

A

fever, myalgia, anorexia, asthenia, maculopapular or petechial rash

37
Q

severe form of dengue

A

dengue hemorrhagic fever

38
Q

dengue hemorrhagic fever found more often in what population

A

otherwise healthy kids

39
Q

possible mechanism for dengue hemorrhagic fever

A

pre-existing antibody to virus enhances binding and uptake of flaviiviruses to macrophages

40
Q

virus causing dengue

A

flaviviridae

41
Q

are dengue mosquitos that vector dengue present in US

A

yes

42
Q

areas reporting sporadic dengue cases

A

texas and florida

43
Q

major endemic areas of yellow fever

A

S America and Africa

44
Q

systemic disease resulting in jaudince from liver involvment

A

yellow fever

45
Q

two phase mosquito bourne virus

A

yellow fever

46
Q

sx of phase I yellow fever

A

flu like sx, n/v

47
Q

sx of phase ii yellow fever

A

jaundice, GI involvement, DIC and shock

48
Q

urban yellow fever spread my man-mosquito-man

A

urban

49
Q

jungle yellow fever spread by

A

mosquito-monkey-mosquito-man

50
Q

type if mosquito carrying yellow fever

A

aedes aegypti

51
Q

granular/sandy looking viruses

A

arenaviruses

52
Q

type of virus passed from rodents to humans

A

arenaviruses

53
Q

major arenavirus in the US

A

lymphatic choriomeningitis

54
Q

clinical manifestation of lypmoocytic choriomenigitis

A

viral pneumibitis or meningitis

55
Q

virus that causes hemorrhagic fevers 92)

A

arenavirus and hantavirus

56
Q

3 arenavirus hemorrhagic fevers

A

lassa, Junin and machupo

57
Q

junin and machupo endemic to

A

South America

58
Q

sx of hantavirus

A

flu like sx, pulmonary edema leading to respiratory failure