Neuro - Pt 1 Intro Flashcards
Parasympathetic Division of the ANS
- Responsible for [] functions: maintenance, conservation, protection of body resources etc.
- Involved with [] autonomic aspect such as digestion
- Also called the [] because the nerves come from the cranium and saccral region of the spinal cord.
- Responsible for anabolic functions: maintenance, conservation, protection of body resources etc.
- Involved with involuntary autonomic aspect such as digestion
- Also called the craniosacral because the nerves come from the cranium and saccral region of the spinal cord.
The Sympathetic division of the ANS
- Responsible for [] functions: expend bodys resources
- Also called the [] division because the nerves come from the thorcic and lumbar regions of the spinal cord.
- Responsible for catabolic functions: expend bodys resources
- Also called the thoracolumbar division because the nerves come from the thorcic and lumbar regions of the spinal cord.
ANS:
- PNS division
- all preganglionic [] are in the []. Preganglionic fibers synapse close to their target
- Postganglionic fibers are []
- SNS division
- All preganglionic axons synapse with the postganglionic neurons in the [] [] or in [] []
- Post ganglionic fibers can be [], [], or [] and distribute widely throughout the body
- PNS division
- all preganglionic bodies are in the CNS. Preganglionic fibers synapse close to their target
- Postganglionic fibers are short
- SNS division
- All preganglionic axons synapse with the postganglionic neurons in the paravertebral chain or in prevertebral ganglia
- Post ganglionic fibers can be short, medium, or long and distribute widely throughout the body
The nervous system is composed of 2 types of cells - [] and [] cells
The nervous system is composed of 2 types of cells - neurons and glial cells
Glial Cells vs Neurons:
- Glial cells are not [], but they do have [] []
- Glial cells are able to divide []
- Glial cellls are more []
- Serve as [] cells to neurons.
- Glial cells are not excitable, but they do have membrane potentials
- Glial cells are able to divide mitotically
- Glial cellls are more abundant
- Serve as supporting cells to neurons.
What are the 2 types of Glial cells in the Peripheral nervous system?
Schwann Cells
Satelitte Cells
What are the 4 glial cells in the CNS?
Oligodendrocyte
Astorcytes
Microglia
Ependymal Cells
Glial cells of Peripheral NS:
- Schwann Cell
- form [] sheaths around nerve fibers only in peripheral NS.
- [] axon is myelinated per Schwann, but there could be [] cells along the axon.
- Satellite Cells
- found in [] and provide []support and help regulate [] around ganglia
- [] junctions exist between satellite cells and adjacent neurons
- Schwann Cell
- form myelin sheaths around nerve fibers only in peripheral NS.
- One axon is myelinated per Schwann, but there could be mulitple cells along the axon.
- Satellite Cells
- found in ganglia and provide structural support and help regulate microenvironment around ganglia
- Gap junctions exist between satellite cells and adjacent neurons
[] form myeling sheaths around nerve fibers only in the CNS. M[] axons can be myelinated by one cell.
Oligodendrocytes form myeling sheaths around nerve fibers only in the CNS. Many axons can be myelinated by one cell.
Astrocytes:
- Most [] neuroglial cell
- Only found in the []
- Serve a [] function and help regulate [] neuronal environment
- Make contact with [] vessels, repair damaged [] tissue, limit diffusion of [], [] synaptic ability by NT uptake, can [] NT
- Highly permeable to [], so it can act as a []
- They are not excitable, but do communicate with [] junctions
- Help maintain [] junctions of capillaries and cover areas of neurons at [] [] []
- Most numerous neuroglial cell
- Only found in the CNS
- Serve a nutritive function and help regulate extracellular neuronal environment
- Make contact with blood vessels, repair damaged CNS tissue, limit diffusion of NT, terminate synaptic ability by NT uptake, can synthesize NT
- Highly permeable to K+, so it can act as a buffer
- They are not excitable, but do communicate with gap junctions
- Help maintain tight junctions of capillaries and cover areas of neurons at nodes of Ranvier
Microglial Cells of CNS:
- Respond to [] and [] and remove debris and foreign particles
- So they ar [] cells
- Respond to injury and inflammation and remove debris and foreign particles
- So they are phagocytic cells
Ependymal Cells
- Line the fluid filled [] of the brain and the [] [] of the spinal cord.
- Found in the [] [] and produce or form [] [] fluid
- Line the fluid filled cavities of the brain and the central canal of the spinal cord.
- Found in the choroid plexus and produce or form cerebral spinal fluid
- [] are groups of cell bodies within the CNS
- [] are groups of cell bodies within the Periphral NS
- [] are nerve fibers
- Nuclei are groups of cell bodies within the CNS
- Ganglia are groups of cell bodies within the Periphral NS
- Axons are nerve fibers
Multipolar Neuron:
- Have several [] and 1 [] extending from the body
- Ex: [] []
- Have several dendrites and 1 axon extending from the body
- Ex: Motor Neuron
Bipolar Neurons
- Have 2 processes - 1 [] and 1 []- extending from the cell body at either end
- Ex: neurons in the [] [] [] []
- Have 2 processes - 1 axon and 1 dendrite- extending from the cell body at either end
- Ex: neurons in the retina of the eye
Pseudo-unipolar Neurons:
- Have a single short process that divides like a [] from the soma to form 1 long process.
- One end receives [] stimuli and acts as a dendrite, the other end acts as an axon an [] with a relay center in []
- Have a single short process that divides like a “T” from the soma to form 1 long process.
- One end receives sensory stimuli and acts as a dendrite, the other end acts as an axon and synapses with a relay center in CNS
Gap Junctions in the Nervous System:
- Allows for []-[] transmission
- [] the major form of communication in the NS
- Found in
- Parts of brain where []-[] communication is needed
- between [] cells
- [] nervous system tissue
- Allows for 2-way transmission
- Not the major form of communication in the NS
- Found in
- Parts of brain where 2-way communication is needed
- between glial cells
- Embryonic nervous system tissue
[] [] are the major form of communication between cells in the nervous system
Chemical synapses
What are the 3 general types of chemical synapses?
Axodendritic
Axosomatic
Axoaxonic
Transmission at chemical synapses is []
Transmission at chemical synapses is unidirectional
Cerebral Sprinal Fluid
- functions include protection, [] removal, and providing a [] environment for neurons and support cells
- [] [] helps form CSF.
- Continually circulates through ventricles and emptys into the [] []
- Is in equillibirum with brain [] fluid
- functions include protection, waste removal, and providing a constant environment for neurons and support cells
- Choroid plexus helps form CSF.
- Continually circulates through ventricles and emptys into the arachnoid villi
- Is in equillibirum with brain interstitial fluid
The CNS is made up of [] matter and [] matter
- Gray matter consists of [] [] and []
- White matter consists of axons that are []
- In the spinal cord, gray matter is on the [] surrounded by [] matter
- In the cerebrum, white matter is on the []and is surrounded by gray matter (called [])
The CNS is made up of gray matter and white matter
- Gray matter consists of cell bodies and dendrites
- White matter consists of axons that are myelinated
- In the spinal cord, gray matter is on the inside surrounded by white matter
- In the cerebrum, white matter is on the inside and is surrounded by gray matter (called cortex)
- The 4 cavities in the adult brain are called []
- The cavity in the adult spinal cord is the [] []
- The 4 cavities in the adult brain are called ventricles
- The cavity in the adult spinal cord is the central canal
Blood-Brain Barrier
- CSF and blood [] [] have the same composition
- [] and [] soluble substances pass freely from blood to CSF (O2, ethanol, ether etc)
- [] and some [] [] are transported from blood to CSF
- blood proteins an macromolcules are []from CSF
- Not all of brain is behind this barrer - [] organs like the pituitary and hypothalamus have [] function and need blood supply.
Blood-Brain Barrier
- CSF and blood do not have the same composition
- Gases and lipid soluble substances pass freely from blood to CSF (O2, ethanol, ether etc)
- Glucose and some amino acids are transported from blood to CSF
- blood proteins an macromolcules are excluded from CSF
- Not all of brain is behind this barrer - circumventricular organs like the pituitary and hypothalamus have neuroendocrine function and need blood supply.
- Cerebrum is the [] portion of the brain and cosists of right and left []
- The hemispheres are connected by a large giber tract called the [] []
- Most structures are found on both sides of the brain, but in some cases, structures which look alike have different functiosn = [] [] []
- Cerebrum is the largest portion of the brain and cosists of right and left hemispheres
- The hemispheres are connected by a large fiber tract called the corpus callosum
- Most structures are found on both sides of the brain, but in some cases, structures which look alike have different functiosn = laterality of function
Left Hemisphere:
- [] functions: Linguistic, analytical, intellectual
- Example: [] ability and languages
-
Symbolic functions: Linguistic, analytical, intellectual
- Example: Mathematical ability and languages
Right Hemisphere:
- [] Functions: Aesthetic, Senses, Mood
- Ex: Musical Ability, Spatial Ability
-
Associative Functions: Aesthetic, Senses, Mood
- Ex: Musical Ability, Spatial Ability
- [] - elevations of folds
- [] - grooves
- Fissures - deep grooves that divide hemispheres into []
- Gyri - elevations of folds
- Sulci - grooves
- Fissures - deep grooves that divide hemispheres into lobes
Brainstem consists of: [], [], and []
Midbrain, pons, and Medulla
Frontal Lobe:
- [] motor control
- Neurons for voluntary control are found in the [] []
- Integration of [] and [] input
- personality, concentration, verbal communication, [] of inappropriate behavior
- Muscles capable of fine, skilled movements have more [] devoted to them tahn muscles for coarse movements.
- Voluntary motor control
- Neurons for voluntary control are found in the precentral gyrus
- Integration of sensory and motor input
- personality, concentration, verbal communication, inhibition of inappropriate behavior
- Muscles capable of fine, skilled movements have more cortex devoted to them than muscles for coarse movements.
If damage occurs to the frontal lobe:
- loss of [] control to the [] side
- Deterioration of higher [] abilities
- Loss of planning and [] solving
- Loss of initiative and []
- loss of motor control to the contralateral side
- Deterioration of higher intellectual abilities
- Loss of planning and problem solving
- Loss of initiative and personality
Parietal Lobe:
- Interpretation of [] and [] sensations, [] interpretation
- Understanding [] and [] words
- Neurons are found in the [] [] []
- If Damaged:
- Decreased [] orientation
- Loss of [] image on the [] side
- Interpretation of cutaneous and muscle sensations, shape interpretation
- Understanding speech and formulating words
- Neurons are found in the post-central gyrus
- If Damaged:
- Decreased spatial orientation
- Loss of body image on the contralateral side
Temporal Lobe:
- [] cortex for hearing (arranged in a [] map)
- [] of sights and sounds
- [] behavior
Temporal Lobe:
- Auditory cortex for hearing (arranged in a tonotopic map)
- Memory of sights and sounds
- Emotional behavior
Damage to Temporal Lobe:
- []-[] Syndrome
- placidity, loss of fear, decreased aggressiveness, hypersexuality, excessive tendency to examine object
- Low threshold for [] - which may produce [] in sights, sounds and smells.
Damage to Temporal Lobe:
-
Kluver-Bucy Syndrome
- placidity, loss of fear, decreased aggressiveness, hypersexuality, excessive tendency to examine object
- Low threshold for siezures - which may produce hallucinations in sights, sounds and smells.
Occipital Lobe
- Primarily responsible for [] and coordination of [] []
- Damage: causes problems with []
Occipital Lobe
- Primarily responsible for vision and coordination of eye movements
- Damage: causes problems with vision
Insular Lobe
- Functions in []
- [] of other cerebral activities
Insular Lobe
- Functions in memory
- Integration of other cerebral activities
How man layers are in a cerebral cortex column?
6
- Layers 1-3 of the cerebral column are involved in [] between different cortical layers
- Layer 4:Receives thalamic []
- Layer 5: Sends cortical [] to brainstema nd spinal cord
- Layer 6: Send [] to the []
- Layers 1-3 of the cerebral column are involved in connections between different cortical layers
- Layer 4:Receives thalamic input
- Layer 5: Sends cortical output to brainstema nd spinal cord
- Layer 6: Send output to the thalamus
Basal Ganglia:
- Masses of [] matter located within the [] matter of the cerebrum, but not part of the []
- Includes the [] nucleus, [], and [] pallidus
- [] with initiation of movement patterns elicted by the motor cortex that connect with [] fiber tracts
- Controls [] movements and dteremines direction, force and speed of movement
- Masses of gray matter located within the white matter of the cerebrum, but not part of the cerebrum
- Includes the Caudate nucleus, putamen, and globus pallidus
- Helps with initiation of movement patterns elicted by the motor cortex that connect with extrapyramidal fiber tracts
- Controls gross movements and deteremines direction, force and speed of movement
T/F - The Basal Ganglia initiate muscle movement.
False
They help execute movements, but cannot initiate.
Caudate Nucleus:
- Part of the [] []
- Functions in [] control of motor activity pattersn as a consequence of []
- Helps the cortex execute [], but learned patterns of movement
Caudate Nucleus:
- Part of the Basal Ganglia
- Functions in cognitive control of motor activity patterns as a consequence of thought
- Helps the cortex execute subconscious, but learned patterns of movement
Lentiform Nucleus:
- Part of the [] [] and contains the [] and [] pallidus
- functions to [] learned, [] patterns of motor behavior
Lentiform Nucleus:
- Part of the Basal Ganglia and contains the putamen and globus pallidus
- functions to control learned complex patterns of motor behavior
Basal Ganglia Disorders:
- [] disease - resting tremor, mask0like face, rigidity, shuffling gait
- [] - sudden jerky and purposeless movement.
- [] - continuous slow writhing movements of the hands, wrist, neck, face etc.
- [] - wild flailing
- Parkinson’s disease - resting tremor, mask0like face, rigidity, shuffling gait
- Chorea - sudden jerky and purposeless movement.
- Athetosis - continuous slow writhing movements of the hands, wrist, neck, face etc.
- Hemiballisumus - wild flailing
Thalamus:
- [] and [] relay and integration center to and from the [] cortex
- All sensory information, except [], pass through here on its way to the cerebral cortex
- Sensory and motor relay and integration center to and from the cerebral cortex
- All sensory information, except smell, pass through here on its way to the cerebral cortex
Hypothalamus
- Vital interface between the [] formation and the [] system
- Involved in maintaining []/[] cycles and [] cycles
- Vital interface between the reticular formation and the endocrine system
- Involved in maintaining sleep/wake cycles and menstrual cycles
Hypothalamus:
- Chronic stimulation of [] hypothalamus causes []
- Osmoreceptors in the hypothalamus stimulate [] and [] release from the [] pituitary
- The hypothalamus is important in []
- The body’ [] is in the hypothalamus
- Chronic stimulation of lateral hypothalamus causes overeating
- Osmoreceptors in the hypothalamus stimulate thirst and ADH release from the posterior pituitary
- The hypothalamus is important in emotions
- The body’ thermostat is in the hypothalamus
Hypothalamus:
- Receives information directly from the internal environment and operates directly on the [] environment
- Via the limbic system, can interact with the [] environment
- Regulates functions which involve [] [] [] or perhaps several organ systems
- Receives information directly from the internal environment and operates directly on the internal environment
- Via the limbic system, can interact with the external environment
- Regulates functions which involve more than one or perhaps several organ systems
Limbic System:
- Structures have many connections with the thalamus and [], called [] [], but not with the cerebral hemispheres.
- More concerned with [] and [] to action and the processes of learning and [].
- Its “older” so we don’t have great control over emotions…
Limbic System:
- Structures have many connections with the thalamus and hypothalamus, called Papez circuit, but not with the cerebral hemispheres.
- More concerned with mood and incentives to action and the processes of learning and memory.
- Its “older” so we don’t have great control over emotions…
Simplified - the cerebrum consists of the [] (new) and the [] system (old)
Simplified - the cerebrum consists of the neocortex (new) and the limbic system (old)
The neocortex regulates precise [] communication wiht environment and formal [] capabilites
The neocortex regulates precise spatiotemporal communication with environment and formal intellectual capabilites
The Cerebellum
- Purely [] in function, best [] of all motor structures
- Involved in the [] of motor output
- provides [] and [] movement
- Connected to…
- joint, [] , [] receptors
- [] cortex
- brainstem and spinal cord
- Controls motion on the [] side
- Purely Motor in function, best informed of all motor structures
- Involved in the stabilization of motor output
- provides smooth and coordinated movement
- Connected to…
- joint, tendon, muscle receptors
- Motor cortex
- brainstem and spinal cord
- Controls motion on the ipsilateral side
Disorders due damge of Cerebellum:
- Defects in [] of movement, not []
- [] of movement
- Defects in excecution of movement, not initiation
- Decomposition of movement