Neuro - Pt 1 Intro Flashcards

1
Q

Parasympathetic Division of the ANS

  • Responsible for [] functions: maintenance, conservation, protection of body resources etc.
  • Involved with [] autonomic aspect such as digestion
  • Also called the [] because the nerves come from the cranium and saccral region of the spinal cord.
A
  • Responsible for anabolic functions: maintenance, conservation, protection of body resources etc.
  • Involved with involuntary autonomic aspect such as digestion
  • Also called the craniosacral because the nerves come from the cranium and saccral region of the spinal cord.
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2
Q

The Sympathetic division of the ANS

  • Responsible for [] functions: expend bodys resources
  • Also called the [] division because the nerves come from the thorcic and lumbar regions of the spinal cord.
A
  • Responsible for catabolic functions: expend bodys resources
  • Also called the thoracolumbar division because the nerves come from the thorcic and lumbar regions of the spinal cord.
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3
Q

ANS:

  • PNS division
    • all preganglionic [] are in the []. Preganglionic fibers synapse close to their target
    • Postganglionic fibers are []
  • SNS division
    • All preganglionic axons synapse with the postganglionic neurons in the [] [] or in [] []
    • Post ganglionic fibers can be [], [], or [] and distribute widely throughout the body
A
  • PNS division
    • all preganglionic bodies are in the CNS. Preganglionic fibers synapse close to their target
    • Postganglionic fibers are short
  • SNS division
    • All preganglionic axons synapse with the postganglionic neurons in the paravertebral chain or in prevertebral ganglia
    • Post ganglionic fibers can be short, medium, or long and distribute widely throughout the body
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4
Q

The nervous system is composed of 2 types of cells - [] and [] cells

A

The nervous system is composed of 2 types of cells - neurons and glial cells

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5
Q

Glial Cells vs Neurons:

  • Glial cells are not [], but they do have [] []
  • Glial cells are able to divide []
  • Glial cellls are more []
  • Serve as [] cells to neurons.
A
  • Glial cells are not excitable, but they do have membrane potentials
  • Glial cells are able to divide mitotically
  • Glial cellls are more abundant
  • Serve as supporting cells to neurons.
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6
Q

What are the 2 types of Glial cells in the Peripheral nervous system?

A

Schwann Cells

Satelitte Cells

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7
Q

What are the 4 glial cells in the CNS?

A

Oligodendrocyte

Astorcytes

Microglia

Ependymal Cells

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8
Q

Glial cells of Peripheral NS:

  • Schwann Cell
    • form [] sheaths around nerve fibers only in peripheral NS.
    • [] axon is myelinated per Schwann, but there could be [] cells along the axon.
  • Satellite Cells
    • found in [] and provide []support and help regulate [] around ganglia
    • [] junctions exist between satellite cells and adjacent neurons
A
  • Schwann Cell
    • form myelin sheaths around nerve fibers only in peripheral NS.
    • One axon is myelinated per Schwann, but there could be mulitple cells along the axon.
  • Satellite Cells
    • found in ganglia and provide structural support and help regulate microenvironment around ganglia
    • Gap junctions exist between satellite cells and adjacent neurons
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9
Q

[] form myeling sheaths around nerve fibers only in the CNS. M[] axons can be myelinated by one cell.

A

Oligodendrocytes form myeling sheaths around nerve fibers only in the CNS. Many axons can be myelinated by one cell.

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10
Q

Astrocytes:

  • Most [] neuroglial cell
  • Only found in the []
  • Serve a [] function and help regulate [] neuronal environment
  • Make contact with [] vessels, repair damaged [] tissue, limit diffusion of [], [] synaptic ability by NT uptake, can [] NT
  • Highly permeable to [], so it can act as a []
  • They are not excitable, but do communicate with [] junctions
  • Help maintain [] junctions of capillaries and cover areas of neurons at [] [] []
A
  • Most numerous neuroglial cell
  • Only found in the CNS
  • Serve a nutritive function and help regulate extracellular neuronal environment
  • Make contact with blood vessels, repair damaged CNS tissue, limit diffusion of NT, terminate synaptic ability by NT uptake, can synthesize NT
  • Highly permeable to K+, so it can act as a buffer
  • They are not excitable, but do communicate with gap junctions
  • Help maintain tight junctions of capillaries and cover areas of neurons at nodes of Ranvier
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11
Q

Microglial Cells of CNS:

  • Respond to [] and [] and remove debris and foreign particles
  • So they ar [] cells
A
  • Respond to injury and inflammation and remove debris and foreign particles
  • So they are phagocytic cells
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12
Q

Ependymal Cells

  • Line the fluid filled [] of the brain and the [] [] of the spinal cord.
  • Found in the [] [] and produce or form [] [] fluid
A
  • Line the fluid filled cavities of the brain and the central canal of the spinal cord.
  • Found in the choroid plexus and produce or form cerebral spinal fluid
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13
Q
  1. [] are groups of cell bodies within the CNS
  2. [] are groups of cell bodies within the Periphral NS
  3. [] are nerve fibers
A
  1. Nuclei are groups of cell bodies within the CNS
  2. Ganglia are groups of cell bodies within the Periphral NS
  3. Axons are nerve fibers
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14
Q

Multipolar Neuron:

  • Have several [] and 1 [] extending from the body
  • Ex: [] []
A
  • Have several dendrites and 1 axon extending from the body
  • Ex: Motor Neuron
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15
Q

Bipolar Neurons

  • Have 2 processes - 1 [] and 1 []- extending from the cell body at either end
  • Ex: neurons in the [] [] [] []
A
  • Have 2 processes - 1 axon and 1 dendrite- extending from the cell body at either end
  • Ex: neurons in the retina of the eye
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16
Q

Pseudo-unipolar Neurons:

  • Have a single short process that divides like a [] from the soma to form 1 long process.
  • One end receives [] stimuli and acts as a dendrite, the other end acts as an axon an [] with a relay center in []
A
  • Have a single short process that divides like a “T” from the soma to form 1 long process.
  • One end receives sensory stimuli and acts as a dendrite, the other end acts as an axon and synapses with a relay center in CNS
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17
Q

Gap Junctions in the Nervous System:

  1. Allows for []-[] transmission
  2. [] the major form of communication in the NS
  3. Found in
    1. Parts of brain where []-[] communication is needed
    2. between [] cells
    3. [] nervous system tissue
A
  1. Allows for 2-way transmission
  2. Not the major form of communication in the NS
  3. Found in
    1. Parts of brain where 2-way communication is needed
    2. between glial cells
    3. Embryonic nervous system tissue
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18
Q

[] [] are the major form of communication between cells in the nervous system

A

Chemical synapses

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19
Q

What are the 3 general types of chemical synapses?

A

Axodendritic

Axosomatic

Axoaxonic

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20
Q

Transmission at chemical synapses is []

A

Transmission at chemical synapses is unidirectional

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21
Q

Cerebral Sprinal Fluid

  • functions include protection, [] removal, and providing a [] environment for neurons and support cells
  • [] [] helps form CSF.
  • Continually circulates through ventricles and emptys into the [] []
  • Is in equillibirum with brain [] fluid
A
  • functions include protection, waste removal, and providing a constant environment for neurons and support cells
  • Choroid plexus helps form CSF.
  • Continually circulates through ventricles and emptys into the arachnoid villi
  • Is in equillibirum with brain interstitial fluid
22
Q

The CNS is made up of [] matter and [] matter

  • Gray matter consists of [] [] and []
  • White matter consists of axons that are []
  • In the spinal cord, gray matter is on the [] surrounded by [] matter
  • In the cerebrum, white matter is on the []and is surrounded by gray matter (called [])
A

The CNS is made up of gray matter and white matter

  • Gray matter consists of cell bodies and dendrites
  • White matter consists of axons that are myelinated
  • In the spinal cord, gray matter is on the inside surrounded by white matter
  • In the cerebrum, white matter is on the inside and is surrounded by gray matter (called cortex)
23
Q
  • The 4 cavities in the adult brain are called []
  • The cavity in the adult spinal cord is the [] []
A
  • The 4 cavities in the adult brain are called ventricles
  • The cavity in the adult spinal cord is the central canal
24
Q

Blood-Brain Barrier

  • CSF and blood [] [] have the same composition
  • [] and [] soluble substances pass freely from blood to CSF (O2, ethanol, ether etc)
  • [] and some [] [] are transported from blood to CSF
  • blood proteins an macromolcules are []from CSF
  • Not all of brain is behind this barrer - [] organs like the pituitary and hypothalamus have [] function and need blood supply.
A

Blood-Brain Barrier

  • CSF and blood do not have the same composition
  • Gases and lipid soluble substances pass freely from blood to CSF (O2, ethanol, ether etc)
  • Glucose and some amino acids are transported from blood to CSF
  • blood proteins an macromolcules are excluded from CSF
  • Not all of brain is behind this barrer - circumventricular organs like the pituitary and hypothalamus have neuroendocrine function and need blood supply.
25
* Cerebrum is the [] portion of the brain and cosists of right and left [] * The hemispheres are connected by a large giber tract called the [] [] * Most structures are found on both sides of the brain, but in some cases, structures which look alike have different functiosn = [] [] []
* Cerebrum is the **largest** portion of the brain and cosists of right and left **hemispheres** * The hemispheres are connected by a large fiber tract called the **corpus callosum** * Most structures are found on both sides of the brain, but in some cases, structures which look alike have different functiosn = **laterality of function**
26
Left Hemisphere: * [] functions: Linguistic, analytical, intellectual * Example: [] ability and languages
* **Symbolic** functions: Linguistic, analytical, intellectual * Example: **Mathematical** ability and languages
27
Right Hemisphere: * [] Functions: Aesthetic, Senses, Mood * Ex: Musical Ability, Spatial Ability
* **Associative** Functions: Aesthetic, Senses, Mood * Ex: Musical Ability, Spatial Ability
28
* [] - elevations of folds * [] - grooves * Fissures - deep grooves that divide hemispheres into []
* **Gyri** - elevations of folds * **Sulci** - grooves * Fissures - deep grooves that divide hemispheres into **lobes**
29
Brainstem consists of: [], [], and []
Midbrain, pons, and Medulla
30
Frontal Lobe: * [] motor control * Neurons for voluntary control are found in the [] [] * Integration of [] and [] input * personality, concentration, verbal communication, [] of inappropriate behavior * Muscles capable of fine, skilled movements have more [] devoted to them tahn muscles for coarse movements.
* **Voluntary** motor control * Neurons for voluntary control are found in the **precentral gyrus** * Integration of **sensory** and **motor** input * personality, concentration, verbal communication, **inhibition** of inappropriate behavior * Muscles capable of fine, skilled movements have more **cortex** devoted to them than muscles for coarse movements.
31
If damage occurs to the frontal lobe: * loss of [] control to the [] side * Deterioration of higher [] abilities * Loss of planning and [] solving * Loss of initiative and []
* loss of **motor** control to the **contralateral** side * Deterioration of higher **intellectual** abilities * Loss of planning and **problem** solving * Loss of initiative and **personality**
32
Parietal Lobe: * Interpretation of [] and [] sensations, [] interpretation * Understanding [] and [] words * Neurons are found in the [] [] [] * If Damaged: * Decreased [] orientation * Loss of [] image on the [] side
* Interpretation of **cutaneous** and **muscle** sensations, **shape** interpretation * Understanding **speech** and formulating **words** * Neurons are found in the **post-central gyrus** * If Damaged: * Decreased **spatial** orientation * Loss of **body** image on the **contralateral** side
33
Temporal Lobe: * [] cortex for hearing (arranged in a [] map) * [] of sights and sounds * [] behavior
Temporal Lobe: * **Auditory** cortex for hearing (arranged in a **tonotopic** map) * **Memory** of sights and sounds * **Emotional** behavior
34
Damage to Temporal Lobe: * []-[] Syndrome * placidity, loss of fear, decreased aggressiveness, hypersexuality, excessive tendency to examine object * Low threshold for [] - which may produce [] in sights, sounds and smells.
Damage to Temporal Lobe: * **Kluver-Bucy** Syndrome * placidity, loss of fear, decreased aggressiveness, hypersexuality, excessive tendency to examine object * Low threshold for **siezures** - which may produce **hallucinations** in sights, sounds and smells.
35
Occipital Lobe * Primarily responsible for [] and coordination of [] [] * Damage: causes problems with []
Occipital Lobe * Primarily responsible for **vision** and coordination of **eye movements** * Damage: causes problems with **vision**
36
Insular Lobe * Functions in [] * [] of other cerebral activities
Insular Lobe * Functions in **memory** * **Integration** of other cerebral activities
37
How man layers are in a cerebral cortex column?
6
38
* Layers 1-3 of the cerebral column are involved in [] between different cortical layers * Layer 4:Receives thalamic [] * Layer 5: Sends cortical [] to brainstema nd spinal cord * Layer 6: Send [] to the []
* Layers 1-3 of the cerebral column are involved in **connections** between different cortical layers * Layer 4:Receives thalamic **input** * Layer 5: Sends cortical **output** to brainstema nd spinal cord * Layer 6: Send **output** to the **thalamus**
39
Basal Ganglia: * Masses of [] matter located within the [] matter of the cerebrum, but not part of the [] * Includes the [] nucleus, [], and [] pallidus * [] with initiation of movement patterns elicted by the motor cortex that connect with [] fiber tracts * Controls [] movements and dteremines direction, force and speed of movement
* Masses of **gray** matter located within the **white** matter of the cerebrum, but not part of the **cerebrum** * Includes the **Caudate** nucleus, **putamen**, and **globus** pallidus * **Helps** with initiation of movement patterns elicted by the motor cortex that connect with **extrapyramidal** fiber tracts * Controls **gross** movements and deteremines direction, force and speed of movement
40
T/F - The Basal Ganglia initiate muscle movement.
False They help execute movements, but cannot initiate.
41
Caudate Nucleus: * Part of the [] [] * Functions in [] control of motor activity pattersn as a consequence of [] * Helps the cortex execute [], but learned patterns of movement
Caudate Nucleus: * Part of the **Basal Ganglia** * Functions in **cognitive** control of motor activity patterns as a consequence of **thought** * Helps the cortex execute **subconscious**, but learned patterns of movement
42
Lentiform Nucleus: * Part of the [] [] and contains the [] and [] pallidus * functions to [] learned, [] patterns of motor behavior
Lentiform Nucleus: * Part of the **Basal Ganglia** and contains the **putamen** and **globus** pallidus * functions to **control** learned **complex** patterns of motor behavior
43
Basal Ganglia Disorders: * [] disease - resting tremor, mask0like face, rigidity, shuffling gait * [] - sudden jerky and purposeless movement. * [] - continuous slow writhing movements of the hands, wrist, neck, face etc. * [] - wild flailing
* **Parkinson's** disease - resting tremor, mask0like face, rigidity, shuffling gait * **Chorea** - sudden jerky and purposeless movement. * **Athetosis** - continuous slow writhing movements of the hands, wrist, neck, face etc. * **Hemiballisumus** - wild flailing
44
Thalamus: * [] and [] relay and integration center to and from the [] cortex * All sensory information, except [], pass through here on its way to the cerebral cortex
* **Sensory** and **motor** relay and integration center to and from the **cerebral** cortex * All sensory information, except **smell**, pass through here on its way to the cerebral cortex
45
Hypothalamus * Vital interface between the [] formation and the [] system * Involved in maintaining []/[] cycles and [] cycles
* Vital interface between the **reticular** formation and the **endocrine** system * Involved in maintaining **sleep/wake** cycles and **menstrual** cycles
46
Hypothalamus: 1. Chronic stimulation of [] hypothalamus causes [] 2. Osmoreceptors in the hypothalamus stimulate [] and [] release from the [] pituitary 3. The hypothalamus is important in [] 4. The body' [] is in the hypothalamus
1. Chronic stimulation of **lateral** hypothalamus causes **overeating** 2. Osmoreceptors in the hypothalamus stimulate **thirst** and **ADH** release from the **posterior** pituitary 3. The hypothalamus is important in **emotions** 4. The body' **thermostat** is in the hypothalamus
47
Hypothalamus: * Receives information directly from the internal environment and operates directly on the [] environment * Via the limbic system, can interact with the [] environment * Regulates functions which involve [] [] [] or perhaps several organ systems
* Receives information directly from the internal environment and operates directly on the **internal** environment * Via the limbic system, can interact with the **external** environment * Regulates functions which involve **more than one** or perhaps several organ systems
48
Limbic System: * Structures have many connections with the thalamus and [], called [] [], but not with the cerebral hemispheres. * More concerned with [] and [] to action and the processes of learning and []. * Its "older" so we don't have great control over emotions...
Limbic System: * Structures have many connections with the thalamus and **hypothalamus**, called **Papez circuit**, but not with the cerebral hemispheres. * More concerned with **mood** and **incentives** to action and the processes of learning and **memory**. * Its "older" so we don't have great control over emotions...
49
Simplified - the cerebrum consists of the [] (new) and the [] system (old)
Simplified - the cerebrum consists of the **neocortex** (new) and the **limbic** system (old)
50
The neocortex regulates precise [] communication wiht environment and formal [] capabilites
The neocortex regulates precise **spatiotemporal** communication with environment and formal **intellectual** capabilites
51
The Cerebellum * Purely [] in function, best [] of all motor structures * Involved in the [] of motor output * provides [] and [] movement * Connected to... * joint, [] , [] receptors * [] cortex * brainstem and spinal cord * Controls motion on the [] side
* Purely **Motor** in function, best **informed** of all motor structures * Involved in the **stabilization** of motor output * provides **smooth** and **coordinated** movement * Connected to... * joint, **tendon**, **muscle** receptors * **Motor** cortex * brainstem and spinal cord * Controls motion on the **ipsilateral** side
52
Disorders due damge of Cerebellum: * Defects in [] of movement, not [] * [] of movement
* Defects in **excecution** of movement, not **initiation** * **Decomposition** of movement