Neuro lV

Question 1

alpha-synuclein defect found in what?

Answer 1

Lewy Body Dementia

Question 2

Classic Triad of MS:

Dx’d by?

Answer 2

SIIN: Scanning speech, Intention tremor, Incontinence, Internuclear Ophthalmoplegia, Nystagmus

• MRI is gold standard
• see increased protein in CSF
• oligoclonal bands, periventricular plaques

Question 3

What is the most common variant of Guillain-Barre?

Answer 3

Acute Inflammatory Demyelinating Polyradiculpathy

- remember AI attacks PNS

Question 4

Dz: demyelination of CNS by destruction of oligodendrocytes and is assoc w JC virus

Answer 4

Progressive Multifocal Leukoencephalopathy

Question 5

Complex vs Simple Seizure

Answer 5

Complex = impaired consciousness

Question 6

“Atonic” generalized seizure

Answer 6

“drop” seizure

Question 7

Absence gen seizure

Answer 7

literally think absence - blank stare

Question 8

Epilepsy is?

Answer 8

recurrent seizures

Question 9

Meningioma, a brain tumor:

• from what cells?
• benign?

Answer 9

from arachnoid cells

• see spindle cells and psammoma bodies
• benign primary tumor

Question 10

Hemangioblastoma, a brain tumor:

• from what area?
• assoc w ?
• histo?

Answer 10

• cerebellum, primary tumor
• assoc w von Hippel-Lindau Syndrome
• can produce EPO –> secondary polycythemia
• so see thin walled capillaries

Question 11

MC childhood supratentorial brain tumor? remnants of what?

Answer 11

Craniopharyngioma - primary

- remnant of Rathke pouch

Question 12

Primary brain tumor found usu in 4th ventricle that can lead to hydrocephalus in children.

Answer 12

Ependymoma

- see perivascular rosettes

Question 13

Malignant primary brain tumor found in children found in the cerebellum.

Answer 13

Medulloblastoma
can METS thru spinal cord
Homer-Wright Rosettes

Question 14

Benign primary brain tumor found in children with characteristic Rosenthal Fibers.

Answer 14

Pilocytic Astrocytoma