GI - ANDERSON Flashcards
What cells secrete Histamine in the ST?
what triggers this?
Gastrin from G cells trigger ECL-cells to release Histamine which stimulates the Proton Pump and release of Gastric H+
What are the cells of the Duodenum and Jejunum that secrete and aid in digestion?
K –> GIP -> stimulate beta cells to release insulin
I -> CCK -> release of bile
S -> secretin -> stim. pancrease and GB to release BICARB
K cells of the SI release?
GIP
I cells of the SI release?
CCK
What is absorbed in the terminal ileum?
What about Iron?
bile salts and B12
- iron is absorbed in the duodenum
Primary Bile Acids
Cholic Acid
Chenodeoxycholic
Secondary Bile Acids are converted from primary via what?
bacteria in the SI
- Deoxycholic
- Lithocholic
Conjugation of bile acids makes BILE SALTS which is done by the _____ with AA’s _____ and ______.
LR
- GLYCINE, TAURINE
RLE enzyme of bile acid synthesis?
7-alpha hydroxylase
B3, NAC, is used in what kinds of rxns?
Xu is called?
DEHYDROGENASE RXNS
Xu –> Pellagra
Remember, B5 is …
CoA
- pantothenic acid
Active form of B6 is…
pyridoxal 5-phosphate
- AA metabolism
- needs Mg as cofactor
Homocysteine -> Methionine
vitamin needed?
B12 - COBALAMIN
B12 also frees _____ to make THF.
FOLATE
Vit C used in what type of RXNs?
HYDROXYLATION