Neural Tissue and Physiology Flashcards
Study of the nervous system
Neurology
What is the primary function of the nervous system?
Communication
Brain and spinal cord
CNS
31 pairs of spinal nerves, 12 pairs of cranial nerves, sensory receptors
PNS
What are the functions of the CNS?
Process and coordinate sensory data, motor commands, higher functions
Control activities of peripheral organs
Motor commands
Includes intelligence, memory
Higher function
Deliver sensory information from PNS sensory receptors to CNS
Afferent division of PNS
Carry motor commands from CNS to PNS muscles and glands
Efferent division of PNS
What are the 3 components of the PNS?
Somatic, autonomic, enteric
Controls voluntary actions, sensory info from skin, joints, skeletal muscles– motor info to skeletal muscle
Somatic
Controls most involuntary actions, sensory info from visceral organs – motor info to smooth muscle, cardiac, muscle, glands
Autonomic
What are the 2 divisions of the autonomic nervous system?
Sympathetic and parasympathetic
Stimulating effect “fight or flight”
Sympathetic
Relaxing effect “rest and digest”
Parasympathetic
Controls the GI tract
Enteric nervous system
What are the 2 general types of nervous cells?
Neurons, neuroglial cells
Cells that send and receive signals
Neuron
Non-conducting cells that support, insulate, and provide nutrients to neurons
Neuroglial cells
Basic function of nervous system, excitable ells that communicate by transmitting electrical impulses
Neurons
What are the 3 main parts of the neuron?
Axon, soma, dendrite
Highly branched extensions of the cytoplasm that functions to conduct electrical signals towards the cell body
Dendrites
Perikaryon, contains nucleus
Soma
Gives gray matter to its color
Nissl bodies
Somas found in aggregates within the CNS
Nucleus
Somas found in aggregates outside the CNS
Ganglion
Functions to conduct nerve impulses away from the cell body to another neuron, muscle or gland
Axon
Axons and dendrites found in bundles within the CNS
Tract
Axons and dendrites found in bundles outside the CNS
Nerve
Where soma connects to axon, area adjacent is where action potential is initiated
Axon hillock
Bulb shaped structures that contain synaptic vesicles filled with neurotransmitters
Axon terminal
Site of communication between a neuron and another cell
Synapse
Neuron that sends the messages
Presynaptic cell
Cell that receives the message
Postsynaptic cell
Small gap that separates the presynaptic membrane and the postsynaptic membrane
Synaptic cleft
Chemical messengers released form postsynaptic cell
Neurotransmitters
Afferent neurons of the PNS; delivers info from sensory receptors to CNS via afferent fibers
Sensory neurons
What are the 2 sensory neurons?
Unipolar and bipolar
Efferent neurons of the PNS; carry instructions from CNS to peripheral effectors via efferent fibers
Motor neurons
What is 1 kind of motor neuron?
Multipolar
Association neurons of the CNS
Interneurons
What are the 2 kinds of interneurons?
Multipolar and anaxonic
Found in brain and spinal cord and special sense organs
Anaxonic neuron
Special sensory neurons found in retina
Bipolar neuron
General sensory neurons of the PNS
Unipolar
Motor neurons found in typical spinal nerve; efferent fibers carry motor impulse away from the CNS
Multipolar neuron
What is the most common type of cell in the nervous system?
Neuroglial cells
What are the 2 types of neuroglial cells in the PNS?
Schwann and satellite
What are the 4 types of neuroglial cells in the CNS?
Astrocytes, microglia, oligodendrocytes, ependymal
Form the blood brain barrier
Astrocytes
Protects neurons from harmful substances in blood
Blood brain barrier
Engulf wastes and destroy microbes
Microglia
Line ventricles of brain and central canal of spinal cord; produce, monitors, and circulates CSF
Ependymal cells
Produce the myelin sheet around axons of neurons in CNS
Oligodendrocytes
Neuroglia cells within the CNS
Oligodendrocytes
Neuroglial cells outside the CNS
Schwann cells
Increases speed of action potential; gives axons white color
Myelin
Junction between myelinated portions of axons
Node of Ranvier
Autoimmune disease; myelin sheath is attacked in CNS
Multiple sclerosis
Regions of CNS with myelinated tracts
White matter
Unmyelinated areas of CNS
Gray matter
Produce myelin sheath around axons and dendrites of neurons in PNS
Schwann cell
Surround cell body of neurons in ganglia, regulate environment around PNS neurons
Satellite cell
Caused by a bacteria that infects the respiratory tract or skin; releases toxin that damages Schwann cells and destroys myelin sheaths of the PNS, leads to sensory and motor problems
Diphtheria
Autoimmune disease that damages the myelin sheaths that are produced by Schwann cells in PNS
Guillai Barre Syndrome
Environmental stimuli are transducer into the common information currency of ___ ____
Nerve impulses
Transmembrane potential of resting cell
Resting potential
Localized change in resting potential caused by a stimulus
Graded potential
Electrical impulse; produced by a large enough graded potential
Action potential
Releases neurotransmitters at presynaptic membrane due to action potential; produces graded potentials in postsynaptic membrane
Synaptic activity
Response of postsynaptic cell
Information processing
Potential difference that results form the unequal distribution of positive and negative ions across the plasma membrane
Transmembrane potential
Is the inside or outside of the cell more negative?
Inside
Concentration gradients of ions across the plasma membrane
Chemical gradient
Due to its chemical gradient, which direction does K want to move through the channel?
outside
Due to its chemical gradient, which direction does Ca want to move through the channel?
Inside
Due to the electrical gradient, which direction does K want to move through the channel?
Inside
Due to the electrical gradient, which direction does Ca want to move through the channel?
Inside
Sum of electrical and chemical forces for a particular ion
Electrochemical gradient
Which way does K move according to the electrochemical gradient?
Out
Which way does Ca move according to the electrochemical gradient?
Inside
Transmembrane potential at which there is no net movement of a particular ion across the cell membrane
Equilibrium potential
How many mV is the equilibrium potential of K?
-90
How many mV is the equilibrium potential of Ca?
66
How does the cell maintain the normal resting potential?
Sodium potassium pump
Pump that maintains resting potential and powered by ATP
Sodium potassium pump
What is the resting membrane potential?
-70 mV
Sodium influx making the membrane potential more positive
Depolarization
Potassium efflux making the membrane potential more negative
Repolarization
More polarized than resting potential
Hyperpolarization