Integumentary System Flashcards
What percentage does the integumentary system make up in our body weight?
16%
What are the 6 functions of the integumentary system?
Protect underlying tissues and organs
excretes salts, water, organic wastes
maintains body temperature
stores lipids
synthesize vitamin D3
Detects touch, pressure, pain, and temperature
What are the 2 parts of the integument?
Cutaneous and accessory structures
Includes the epidermis and dermis
Cutaneous
Includes the hair, nails, and exocrine glands
Accessory structures
Glands that secretes onto surfaces and ducts
Exocrine gland
What are the 2 regions of the cutaneous membrane?
Epidermis and dermis
Outermost protective shield, 4-5 layers of stratified squamous cells, avascular
Epidermis
What part of the cutaneous membrane is the origin of accessory structures?
Epidermis
What type of tissue make up the epidermis?
Epithelium
What type of tissue make up the dermis?
Connective
Tough leathery layer, vascular
Dermis
What are the functions of the hypodermis?
Stabilize and support integument
What type of tissues make up the hypodermic?
Areolar and adipose
What does loose connective tissues function for the hypodermic?
Insulation, shock absorption, energy storage
How many layers does thin skin have and where is it located?
4; most of body
How many layers does the thick skin have and where is it located?
5; palms, fingertips, soles of feet
What are the layers of the epidermis from superficial to deep?
Stratum corneum, Stratum lucidum, stratum granulosum, stratum spinosum, stratum basale
Mitotic stem cells; 25% of these cells are melanocytes
Stratum basale
Infrequent mitosis
Stratum spinosum
Transition layer where keratinization begins
Stratum granulosum
Present only in thick skin
Stratum lucidum
15- 30 cells thick, continuously shed, keratinized
Stratum corneum
Formation of a superficial layer of dead, tough, protective cells with keratin
Keratinization
How long does it take for cells to move from the stratum basale to the stratum corneum?
2 weeks
What are the 2 influences on skin color?
Pigment, degree of dermal blood circulation
Yellow-black pigment that are stored in transport vesicles and transferred to keratinocytes
Melanin
What is melanin produced by?
Melanocytes
No melanin production
Albinism
Melanocytes in certain areas lose their ability to produce melanin
Vitiligo
UV radiation is used in _____ synthesis
Vitamin D3
What does melanin protect us from?
UV radiation
Least malignant type of skin cancer that rarely spreads
Basal cell carcinoma
Rare type of skin cancer that is the leading causes of death of skin cancer
Melanoma
Liver and kidneys convert vitamin D3 into _____
Calcitriol
Aids in absorption of calcium
Calcitriol
What can an insufficient amount of vitamin D3 cause?
Rickets
What are the 2 major layers of the dermis?
Papillary and reticular
Layer of dermis that is made of loose connective tissue and contains capillaries and feeds the epidermis
Papillary
Layer of dermis that is made of deep irregular connective tissue, elastic and collagen fibers
Reticular layer
Dead keratinized and epithelial cells
Hair
Surrounds and produces hair
Hair follicle
What is the function of hair?
Protection, reduction of heat loss, sense of light touch
Secretes sebum and is an exocrine gland
Sebaceous gland
Prevents dehydration of hair and skin; inhibits bacterial and fungal growth
Sebum
Inflammation of the sebaceous gland
Acne
Sweat gland that helps with thermoregulation, waste removal, active throughout live and is found all over skin
Eccrine (merocrine) sweat glands
Sweat gland that is associated with sexual excitement, active during puberty, limited distribution
Apocrine sweat glands
Dead epidermal cells packed with keratin
Nails
What are the effects of aging on integument?
Epidermal and dermal thinning, decrease in melanocyte activity, increase risk of infection and sun damage, slower skin repair, decreased vitamin D3 synthesis, diminished blood supply, decreased glandular activity
Hormone that increases epidermal thickness, accelerate wound healing, increase number of cells protecting against cancer cells sand pathogen
Sex hormone
Hormone that stimulates collagen synthesis, stimulates basal cell division
Growth hormone
Hormone that stimulates basal cell division, accelerates production of keratin
Epidermal growth factor
Why does the skin increase in number of cell layers during skin injury/healing?
Mechanical stress
Why does the skin have really good regenerative ability?
Stem cells in epidermis and dermis
During skin injury what are the risks?
Infection, dehydration, thermoregulation decreases, scar tissue
Replacement of integument with acellular, inflexible, tissue which lacks glands and hair follicles
Scar tissue
Raised scar tissue
Keloid
Where are melanocytes located?
Stratum Basale
What dermis layer is affected by stretch marks?
Reticular layer