Muscles (KT) Flashcards
The scientific study of muscles
Myology
How much total body mass does muscle account for?
45%- responsible for most of the work generated by the body
Functions of Muscles (5)
- Maintain posture and body position
- Movement
- Heat production
- Guard orifices
- Support visceral organs
Properties of Muscle Tissue (4)
- Excitability
- Contractility
- Extensibility
- Elasticity
The ability to receive and respond to electrical or chemical stimuli
Excitability
The ability to shorten forcibly when stimulated
Contractility
The ability to be stretched without damaging the tissue
Extendibility
The ability to return to original shape after being stretched
Elasticity
Muscle composition (5)
Muscles are organs… The consist of…
- Connective Tissue
- Arteries/Veins
- Nerves
- Lymphatics
- Contractile muscle cells
Skeletal Muscle Characteristics (7)
- Attaches to bone, skin, or fascia
- Striated with light and dark bands
- Voluntary control
- Long, thin, and multinucleate fibers
- Arranged into packages that attach to and cover the bony skeleton
- Contracts rapidly, but tire easily
- Exert great force
Fiber= 1 muscle cell
The main portion of a muscle
Belly/Gaster
Where is the belly of the muscle attached?
Belly is attached to tendons, and then tendons are attached to bones
- Dense irregular connective tissue that is around muscle
- Holds it in place and separates it from other muscles
Deep Fascia
- Loose connective tissue beneath skin
- Surrounds several muscles
Subcutaneous Fascia
How are skeletal muscles organized? (General)
- Many muscle fibers are bundled together into groups called fascicles
- 10-100 muscles fibers per fascicles
- Several fascicles make up a muscle
Skeletal muscle connective tissue that surrounds the whole muscle
Epimysium
Skeletal muscle connective tissue that surrounds the fascicles
Perimysium
Skeletal muscle connective tissue that separates individual muscle fibers (cells)
Endomysium
All connective tissue extends beyond the muscle belly to form the….
Tendon
Tendons that from thick flattened sheets are called…
Aponeuroses
Embryonic cells that fuse to form muscle fibers… (this is why they are long and multinucleate)
Myoblasts
Myoblasts that do not fuse become…
Myosatellite cells
What is the function of Myosatellite cells?
Assist in repair of damaged cells
Fiber cytoplasm
Sarcoplasm
Plasma membrane in a fiber
Sarcolemma
Extensions of the sarcolemma into the sacroplasm
Transverse (T) Tubule
Contractile organelles that…
- Extend the length of fiber
- Surrounded by the sarcoplasmic reticulum
Myofibrils
- Surround the myofibrils
- Similar to the ER
- Contain calcium ions
Sarcoplasmic Reticulum
What is the functional unit of a myofibril
Sarcomere
What are the 2 components of sarcomeres?
- Thick Filaments
2. Thin Filaments
What is the component of Thick Filaments?
-Myosin
What is the component of myosin?
- Twisted protein with globular heads
- 1.6 um long
- 500 per thick filament
What are the components of Thin Filaments? (2)
- Actin
2. Regulatory Proteins
Components of Actin… (2)
- Structural Proteins
2. Coiled “beads”
Components and function of Regulatory Proteins… (3)
- Allow/Prohibit attachment between actin and myosin
- Tropomyosin
- Troponin
Cause the striated appearance
Sarcomere bands
What are the 4 kinds of sarcomere bands?
- A Band
- I Band
- H Band
- Zone of Overlap
Type of band that includes the entire thick filament range
A Band
Type of band that includes only thin filaments
I Band
Type of band that includes only thick filaments
H Band
Type of band that includes both filaments
Zone of Overlap
These structures divide and flank the sarcomere
Sarcomere Lines
What are the 2 types of sarcomere lines?
- Z line
2. M Line
This type of sarcomere line…
- Is at the end of the sarcomere
- Made of actinin protein
- Anchors thin filaments
Z Line
This type of sarcomere line…
- Is in the middle of the sarcomere
- Stabilizes thick filaments
M Line
Structural Protein that…
- Anchors a thick filament to a Z line
- Accounts for elasticity and extensibility
Titin
Structural Protein that…
-Holds the F actin together on
thin filaments
Nebulin