Integumentary System (KT) Flashcards
What are the 2 components of the integumentary system?
- Cutaneous Membrane
2. Accessory Structures
What is included in the cutaneous membrane? (2)
- Epidermis
2. Dermis
What is included in the Accessory Structures? (3)
- Hair
- Nails
- Glands
Functions of the Integumentary System? (4)
- Protection
- Heat regulation
- Excretion of urea and uric acid
- Synthesizes Vitamin D
What does the integumentary system protect the body from? (6)
- Mechanical Damage
- Chemical Damage
- Bacterial Damage
- Thermal Damage
- UV radiation
- Desiccation
Characteristics of the epidermis (4)
- Stratified squamous epithelium
- Lacks blood vessels but can divide
- As new cells grow, the older cells get pushed to the surface
- Outer most layers are dead
The 4 cell types of the Epidermis
- Keratinocytes (90%)
- Melanocytes (8%)
- Langerhan Cells
- Merkel Cells
Characteristics of…
Keratinocytes
- produce keratin
- provide protection
Characteristics of…
Melanocytes
- produce melanin pigments which protects against UV radiation
- melanin transferred to other cells with long cell processes
Characteristics of…
Langerhan Cells
- from bone marrow
- part of an immune response
Stem cells divide to produce __________ at the basal lamina
Keratinocytes
As keratinocytes are pushed up towards the surface…
- They will fill with keratin and oils
- They slowly die
- Its a 4 week journey unless the outer layers are removed by abrasion
Layers of the Epidermis (5)
- Stratum Germinativum
- Stratum Spinosum
- Stratum Granulosum
- Stratum Lucidum
- Stratum Corneum
Characteristics of Stratum Germativum (2)
- Deepest single layer of cells
2. Combination of merkel cells, melanocytes, kerytinocytes and stem cells that divide repeatedly
How are cells attached in the Stratum Germativum layer?
Cells attached to each other and to the basal lamina by desmosomes & hemidesmosomes
Characteristics of the Stratum Spinosum (3)
- 8-10 cell layers held together by desmosomes
- Melanin taken in by the phagocytosis from near by melanocytes
- During slide preparation cells shrink and look spiny
Characteristics of Stratum Granulosum (3)
- 3 to 5 layers of flat dying cells
- Show nuclear degeneration
- Contain dark-staining keratohyalin granules
What are keratohyalin granules?
They release lipids that repel water
Characteristics of Stratum Lucidum (2)
- Seen in think skin on palms and soles of feet ONLY
2. 3 to 5 layers of clear, flat, dead cells
Characteristics of Stratum Corneum (4)
- 25 to 30 layers of flat dead cells filled with keratin and surrounded by lipids
- Continuously shed
- Barrier to light, heat, water, chemicals and bacteria
- Friction stimulates callus formation
2 types of Skin Thickness
- Thick Skin
2. Thin Skin
Think Skin
- Palmar and Planter surface
- About 30 layers of Stratum Corneum
- All 5 layers
Thin Skin
- Rest of body surfaces
- Fewer layers of Stratum Corneum
- No Stratum Lucidum
- Stratum germativum forms ridges that extend into the dermis
- Increases area of contact for better grip
Epidermal Ridges
-Produced in the epidermis by melanocytes
Melanin
Facts about Melanocytes
- Same number of melanocytes in everyone but different amounts of pigment produced
- UV in sunlight increases melanin production
Melanin production is in response to…
Melanocyte Stimulating Hormone
Melanocytes convert _________ to melanin?
Tyrosine
True/ False: There are several different types of melanin.
True
Typical brown or black melanin
Eumelanin
Red brown version of melanin
Pheomelanin
Freckles or liver spots…
Melanocytes in a patch
Benign localized overgrowth of melanocytes
Nevus or mole
Inherited lack of tyrosine; no pigment
Albinism
- Yellow orange pigment (precursor of Vitamin A)
- Found in stratum Corneum & Subcutaneous
Carotine