Misc Flashcards

1
Q

glycoproteins that are normally synthesized by virus-infected cells with a wide range of anti viral & anti tumor props

A

Interferons

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2
Q

tx for chronic HepB, HepC, Kaposi sarcoma, hairy cell leukemia, condyloma acuminatum, renal cell carcinoma, malignant melanoma

A

IFN alpha

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3
Q

tx for multiple sclerosis

A

IFN beta

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4
Q

tx for chronic granulomatous disease

A

IFN gamma

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5
Q

Hep C therapy

A

Ribavirin, Simeprevir, Sofosbuvir

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6
Q

inhibits synthesis of guanine by competitively inhib inosine monophosphate dehydrogenase
tx chronic HCV & RSV

A

Ribavirin

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7
Q

HCV protease inhibitor - prevents viral replication

tx chronic HCV in combo w/ ribavirin & peginterferon alpha

A

Simeprevir

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8
Q

inhibit HCV RNAdep RNApol as a chain terminator

tx chronic HCV in combo w/ ribavirin +- peginterferon alpha

A

Sofosbuvir

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9
Q

abx to avoid in pregnancy

‘SAFe Children Take Really Good Care’

A

Sulfonamides, Aminoglycosides, Fluoroquinolones, Clarithromycin, Tetracyclines, Ribavirin, Griseofulvin, Chloramphenicol

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