Misc Flashcards
glycoproteins that are normally synthesized by virus-infected cells with a wide range of anti viral & anti tumor props
Interferons
tx for chronic HepB, HepC, Kaposi sarcoma, hairy cell leukemia, condyloma acuminatum, renal cell carcinoma, malignant melanoma
IFN alpha
tx for multiple sclerosis
IFN beta
tx for chronic granulomatous disease
IFN gamma
Hep C therapy
Ribavirin, Simeprevir, Sofosbuvir
inhibits synthesis of guanine by competitively inhib inosine monophosphate dehydrogenase
tx chronic HCV & RSV
Ribavirin
HCV protease inhibitor - prevents viral replication
tx chronic HCV in combo w/ ribavirin & peginterferon alpha
Simeprevir
inhibit HCV RNAdep RNApol as a chain terminator
tx chronic HCV in combo w/ ribavirin +- peginterferon alpha
Sofosbuvir
abx to avoid in pregnancy
‘SAFe Children Take Really Good Care’
Sulfonamides, Aminoglycosides, Fluoroquinolones, Clarithromycin, Tetracyclines, Ribavirin, Griseofulvin, Chloramphenicol