HIV therapy Flashcards
1
Q
Indinavir
A
protease inhibitor
2
Q
Fosamprenavir
A
protease inhibitor
3
Q
HAART
A
3 drugs: 2 NRTIs + 1 of the following… NNRTI or protease inhibitor or integrase inhibitor
4
Q
Lopinavir
A
protease inhibitor
5
Q
Zidovudine
A
NRTI used for general prophyl & during pregnancy to reduce risk of fetal transmission
6
Q
Emtricitabine
A
NRTI
7
Q
prevent maturation of new viruses by inhib HIV1 protease from cleaving polypeptide products of HIV mRNA into functional parts
A
Protease inhibitors
8
Q
Ritonavir
A
protease inhibitor- boosts other drug conc. by inhib cytochrome P450
10
Q
competitively inhib nucleotide binding to RT & terminate DNA chain (lacks 3’OH)
must be phosphorylated to be active
A
NRTIs
11
Q
Darunavir
A
protease inhibitor
11
Q
Didanosine
A
NRTI
12
Q
Saquinavir
A
protease inhibitor
13
Q
Lamivudine
A
NRTI
14
Q
Tenofovir
A
NRTI
15
Q
Abacavir
A
NRTI
