Microbiology 2: G.I Infections

Question 1

Name 3 organisms that cause an inflammatory diarrhoea ?

Answer 1

Campylobacter. Jejuni
Shigella.spp
Non-typhoidal salmonella serotypes

Question 2

Name an organism that causes a secretory diarrhoea ?

Answer 2

Vibrio cholerae

Question 3

What is the difference between secretory and inflammatory diarrhoea ?

Answer 3

Inflammatory diarrhoea also has a fever and white blood cells in stool sample

Question 4

Which bacteria is commonly found in re-heated fried rice ?

Answer 4

B.Cereus

Question 5

List the 3 Cs of antibiotics commonly responsible for causing Pseudomembranous colitis ?

Answer 5

Cephalosporins
Ciprofloxacin
Clindamycin

Question 6

Name 2 drugs used to treat Pseudomembranous colitis ?

Answer 6

Metronidazole

Vancomycin

Question 7

Which organism present in refrigerated food causes gastroenteritis with fever and particularly affects pregnant women ?

Answer 7

Listeria monocytogenes

Question 8

Which organism is commonly responsible for traveler’s diarrhoea ?

Answer 8

ETEC- Etoxogenic E.Coli

Question 9

Young child visited petting farm and now presents with haemorrhagic stools and Renal failure.

Which organism is responsible?

Answer 9

EHEC - haemoragic E.Coli 0157:H7

Question 10

Which organism is found in raw seafood and commonly causes self limiting diarrhoea in japan ?

Answer 10

Vibrio. Parahaemolyticus

Question 11

Which organism causes cellulitis In shellfish handlers which can cause fatal septicaemia ?

Answer 11

VIbrio. Fulnificus

Question 12

Which comma shaped bacteria can cause abdominal pain and watery diarrhoea and is commonly transmissited by eating BBQ meat ?

Answer 12

Campylobacter

Question 13

Which protozoal organism with 4 nuclei present in unboiled water causes “flask-shaped” ulcers, tenesmus, RUQ pain, dysentery and liver abscesses ?

Answer 13

Entamoeba. Hystolytica

Question 14

Which Protozoal organism causes severe diarrhoea in the immuno compromised and is diagnosed by the presence of Oocysts in the stool seen by staining with Modified Kinyoung acid fast stain ?

Answer 14

Cryptosporidium.Parvum

Question 15

Which dsRNA “wheel shaped” virus causes secretory diarrhoea in children ?

Answer 15

Rotavirus

Question 16

Which virus causes outbreaks and often requires hospital wards to be closed?

Answer 16

Norovirus

Question 17

Which virus causes non bloody diarrhoea in <2 year olds or immunocompromised patients ?

Answer 17

Adenovirus

Question 18

List 2 ways that Salmonella is commonly transmitted ?

Answer 18

Eating infected meats (often raw chicken)

Reptiles (you often see recurrent infections)

Question 19

List differences in the presentation of Salmonella enteritidis and Salmonella typhi ?

Answer 19

Enteritidis: non-bloody Diarrhoea, no fever, self-limiting, stool culture +ve

Typhi: Constipation, typhoid fever, can cause bacteraemia, affects sickle cell patients more, splenomegally and rose spots, blood culture +ve

Question 20

What is dysentery ?

Answer 20

Infection of the intestines resulting in severe diarrhoea with blood and mucous

Question 21

Name a gram possitive coccus bacteria that causes food poisoning ?

Answer 21

S.aureus

Question 22

Name an organism that affects the ileum, appendix and colon. It invades peyer’s patches leading to mesenteric lymph node enlargement with necrotising granulomas. Complication can include peritonitis, pharyngitis and pericarditis.

Answer 22

Yersinia

Question 23

Which organism causes “rice water stools” ?

Answer 23

Cholera

Question 24

Which organism causes an afebrile, explosive diarrhoea and vomiting, abdominal pain and bloating, steatorrhea with cysts in the stool ?

Answer 24

Giardiasis

Question 25

Which organism causes a rapid onset of nausea and vomiting after eating buffet ham. Thought to be due to a heat stable preformed toxin ?

Answer 25

S.aureus

Question 26

S-shaped microaerophillic bacteria in stool culture ?

Answer 26

Campylobacter

Question 27

Which gram -ve bacteria often gives rise to travellers diarrhoea ?

Answer 27

E.Coli

Question 28

Which organism often found in refrigerated food or unpasteurised dairy products shows "tumbling motility" on microscopy and can cause gastroenteritis outbreaks ?

Answer 28

Listeria Monocytogenes Pregnant women need to be careful with eating soft cheeses. Neonates and immunocompromised are especially susceptible and can get sepsis, meningitis and encephalitis.

Question 29

Which organism can cause HUS ?

Answer 29

EHEC 0157:H7

Question 30

Which 'comma' organism is responsible for profuse watery diarrhoea ?

Answer 30

V.Cholerae

Question 31

Which organism is "pear shaped" and causes foul smelling steatorrhoea with cysts visible on microscopy ?

Answer 31

Giardia Lamblia

Question 32

Which bacteria transmitted via dog faeces can cause complications such as GBS (Guillan Barre Sydrome) and Reiter's syndrome ?

Answer 32

Campylobacter Jejuni

Question 33

Which organism can cause watery diarrhoea + abdominal cramps after eating reheated meats? This organism can also cause gas gangrene and mainly acts on the small bowel.

Answer 33

Clostridia Perfringens

Question 34

Which organism mainly affects the distal ileum and colon causing a fever and painful, bloody diarrhoea ?

Answer 34

Shigella