Microbiology 18: Fungal Infections Flashcards

1
Q

Name 3 yeasts ?

A

Candida
Cryptococcus
Histoplasma

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2
Q

Name 2 Moulds ?

A

Aspergillus

Dermatophytes

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3
Q

What does it mean if a fungi is dimorphic?

A

It can change between yeasts and moulds depending on environmental conditions

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4
Q

Which groups of people are particularly at risk of systemic candidiasis ?

A

Very low birth weight infants
Immunocompromised
Patients on ITU
Patients receiving TPN

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5
Q

How do you differentiate Candida Albicans from other Candidas ?

A

They form Germ tubes

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6
Q

What is the candida infection that affects skin folds in children called ?

A

Intertrigo

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7
Q

Which yeast infection is particularly more common in HIV +ve patients ?

A

Cryptococcus

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8
Q

Which yeast shows capsules when stained on India ink ?

A

Cryptococcus

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9
Q

Name the Cryptococcus Neoformans variant which causes meningitis in immunosupressed people especially around SE asia and Australia where there are Eucalyptus trees ?

A

Cryptococcus Neoformans var. gatii

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10
Q

Which antigen if detected in serology can suggest aspergillus infection ?

A

Galactomannan

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11
Q

Name an aggressive disease caused by a mould which is considered a surgical emergency and requires debridement ?

A

Mucormycosis

Characterised by cellulitis of the orbit and face which progresses with discharge and black pus from the palate and nose

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12
Q

A hyper pigmented lesion on the back which has a “spaghetti and meatballs” appearance on microscopy and orange fluorescence under Wood’s light.

Most likely organism ?

A

M.furfur

This is pityriasis versicolour

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13
Q

A rose gardener gets pricked by a rose thorn on his arm. This leads to small nodular lesions on the surface which start to ulcerate.

Most likely organism ?

A

Sporothrix schenkii (rose gardener’s disease)

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14
Q

This fungus causes loss of hair and scaly red lesions on the scalp.

Most likely organism ?

A

Tinea capatis

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15
Q

List 3 types of infections caused by Tinea ?

A

Athletes foot (Tinea pedis)
Ringworm (Tinea Corporis)
Tinea capatis

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16
Q

What is the main treatment for Aspergillus infection ?

A

Ampoterecin B

17
Q

Which anti fungal is used to treat Candida infection ?

A
Echinocandins 
or Fluconazole (but losing sensitivity)
18
Q

Which anti fungal is used to treat Cryptococcus infection ?

A

Ampoterecin B

19
Q

Which organism causes Pityriasis versicolour ?

A

Malassezia. FurFur

20
Q

Which organism causes seborrheic dermatitis ?

A

Malassezia globosa