Microbiology 17: Neonatal and childhood infections Flashcards
List 4 infectious diseases screened for during pregnancy ?
Hep B
HIV
Rubella
Syphilis
What is the most common cause of congenital deafness in the UK ?
CMV
Which disease is transmitted by cat poo ?
Toxoplasmosis
What are some of the signs of congenital toxoplasmosis infection ?
60% asymptomatic Choroidoretinitis Microcephaly Seizures Hepatosplenomegally Intracranial calcification Low IQ + deafness (later)
What is the classical triad of signs of congenital rubella infection ?
Cataracts
Congenital heart disease
Deafness
What signs do you get with congenital HSV infection ?
Blistering rash
Meningoencephalitis
Disseminated infection
What can Chlamydia trachomatis cause in the neonate ?
Neonatal conjunctivitis
Pneumonia
Which 3 organisms most commonly cause early onset (<48h) sepsis in the neonate ?
GBS (group b streptococcus)
E.coli
Listeria monocytogenes
Which organism most commonly causes late onset (48-72h) sepsis in the neonate ?
Coagulase negative staphylococci (e.g s.epidermidis, s.saprophyticus)
Which antibiotics are often used to treat early onset sepsis in the neonate?
Benzylpenicillin (treats GBS) + gentamicin (treats e.coli)
Which bacteria classically causes superinfection with chicken pox ?
Invasive Group A streptococcus
Bullous myringitis (vesicles on the tympanic membrane) and otitis media are suggestive of which organism ?
Mycoplasma Pneumoniae
Extra pulmonary manifestation
Which bacteria causes whooping cough ?
Bordatella Pertussis