Haematology 8: Lymphoma 1 Flashcards

1
Q

Which is more common Hodgkin lymphoma or NHL ?

A

NHL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Where does VDJ recombination occur ?

A

Bone marrow

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Where does class switching occur ?

A

Germinal centres

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Which lymphoma is associated with chronic H.pylori infection?

A

Gastric MALT lymphoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Which lymphoma is associated with Coeliac disease ?

A

EATL - enteropathy-associated T cell Lymphoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Which virus causes adult T cell lymphoma ?

A

HTLV1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Which CD marker is a marker of Germinal centre B cells ?

A

CD10

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What does Follicular lymphoma look like on Histology ?

A

Follicular pattern- lots of follicles in lymph tissue

BCL2 possitive

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Which 2 Lymphomas is associated with EBV infection ?

A

Burkitt’s lymphoma

Hodgkin’s lymphoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Which lymphoma has a starry-sky appearance

A

Burkitt’s lymphoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Which Lymphoma is particularly prevelant in the Caribbean and japan ?

A

Adult T cell Lymphoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Which cell allows differentiation between Hodgkin’s and NHL lymphoma ?

A

Reed-sternberg cells (seen in Hodgkin’s)

looks like Owl eyes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Describe the staging of Hodgkin Lymphoma from 1-4 A/B

A

Stage 1: one group of nodes
Stage 2: >1 group of nodes same side of diaphragm
Stage 3: nodes above and below the diaphragm
Stage 4: extranodal spread

A: without any B symptoms
B: Fever, Unexplained weightloss of more than 10% in 6 months, night sweats

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Name the staging system in Hodgkins lymphoma ?

A

Ann-Arbor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly