Micro Finals-virus Flashcards
Birnaviridae
- naked RNA
- icosahedral
- replicate in cytoplasm
- fecal/Oral route
- macrophages,p/lymphoid cells in cascade,duodenum,jejunum
- b-lymphocytes main target
- infectious bursa disease in young chicks
Orthomyxoviridae
- enveloped RNA
- helical
- replicate in nucleus, release by budding
- haemagglutinin, neuramidase
- influenza causing virus
- highly mutational, “mixing vessels”
- fecal/oral route
- replication in intestinal tract
- mainly respiratory disease
- lungs target organ
- avian, swine, equine influenza
Paramyxoviridae
-enveloped helical RNA
-large pleomorphic
-replication in cytoplasm, release by budding
-no recombination, only mutation
-affinity for mucus membranes
-direct contact/aerosols
-multiplication in pharyngeal/mandibular LN
-leukopenia and immunosuppression
Paramoxivirinae
Avila virus-New Castle Disease, poultry
Henipavirus-Nipah virus
Morbilivirus-peste de pestis in ruminants, rinderpest, canine distemper virus
Rhabdoviridae
-enveloped helical RNA
-replication in cytoplasm, release by budding
Rabies/Lyssa viruses
Vesicular stomatitis viruses-similar to foot/mouth, differential diagnosis
Bornaviridae
-enveloped spherical RNA
-replication in nuclei, release by budding
-ingestion or inhalation
Born a disease- neural disease in young horses, T-cell mediated meningeoencephalitis
Buyunaviridae
-enveloped spherical RNA
-replication in cytoplasm, release by exocytosis
-cytolysis in vertebrates
-vector borne, infected tissues, transplacental
-haemorrhagic fevers
Phlebovirus-rift valley fever
Nairovirus-Nairobi sheep disease
Orthobuynavirus- akabane mm, congenital defects
Picornaviridae
-naked icosahedral RNA
-replication in cytoplasm
-cytolytic infection
-inhalation, ingestion, insemination, inoculation, abraded skin
Enterovirus-swine vesicular disease virus, notifiable
Sapelovirus-porcine sapelovirus, severe encephalomyelitis
Tremovirus- avian encephalimyelitis, neurological signs
Apthovirus-foot and mouth disease, notifable
Caliciviridae
-small naked icosahedral RNA
-replication in cytoplasm, release by cell lysis
-respiratory disease, vesicular lesions, necrotizing hepatitis, gastroenteritis
Vesicular exanthema virus- vesicular disease in pigs, similar to foot/mouth
Feline calicivirus-URT disease in cats, vesicles in mouth, similar to feline herpesvirus 1
Rabbit haemorrhagic disease virus- mononuclear phagocytes main target, necrotizing hepatitis
Astroviridae
-small naked icasohedral RNA
-replication in cytoplasm, release by cell lysis
-fecal/oral route
Mamastovirus-gastroenteritis in mammals
Avastrovirus-hepatitis, nephritis, enteritis in avians
Coronaviridae
-enveloped pleomorphic RNA
-replication in cytoplasm, release by exocytosis
-tropism for respiratory and intestinal epithelium
Feline coronavirus-Feline infectious peritonitis, replication in enterocytes , effusive or non-effusive form
Canine coronavirus-diarrhea in dogs
Transmissible gastroenteritis virus-diarrhea and vomiting in pigs
Porcine epidemic diarrhea virus
Porcine haemagglutinating encephalomyelitis virus- nervous disease or vomiting in pigs
Avian coronavirus- infectious bronchitis, notifiable
Arteriviridae
-medium sized enveloped icosahedral RNA
-replication in cytoplasm, release by exocytosis
-macrophages and endothelial cells
-she’d in secretions
Arterivirus-equine arthritis virus/EAV, porcine porcine reproductive/respiratory syndrome virus/PRRS
Flaviviridae
-enveloped icosahedral RNA
-replication in cytoplasm, release by budding
Flavivirus-require vectors, West Nile virus
Pestivirus-border disease of lambs, bovine viral diarrhea/BVD, classical swine fever/SSFV=notifiable (similar to African swine fever)
