Memory Disorders Flashcards

1
Q

subject memory complaints predicts what?

A

predate formal deficits in some dementia

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2
Q

Case of HM was?

A

bilateral mediall temporal lobe resection = no long term memory creation, amnesia, but intact procedural and working memory

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3
Q

Immediate memory is?

A

short=term, keeping info like digits in our heads and manipulate if need be

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4
Q

long term memory is?

A

storing information over minutes/hours/years

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5
Q

what is non-declarative memory?

A

skills/habits

priming/classical conditioning

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6
Q

what is 2 kinds of declarative memory?

A

episodic: events
semantic: facts (banana is yellow)

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7
Q

semantic memory contextual?

A

Nope

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8
Q

3 important brain areas for declarative memory? damage does what?

A
  1. Hippocampus
    2.entorhinal cortex
  2. perirhinal cortex
    damage to any of the three causes memory deficits
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9
Q

Right hippocampus better for?

A

non verbal memory: faces, visuospatial associations

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10
Q

left hippocampus better for?

A

verbal: list learning/story recall

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11
Q

4 big causes of memory impairment?

A
  1. degenerative disorders
  2. cerebrovascular disorders
  3. paroxysmal/transient (eg. trauma)
  4. surgical resection
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12
Q

what happens to hippocampus in temporal lobe epilepsy? histologically and clinically?

A
hippocampal sclerosis (CA1)
declarative memory deficit
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13
Q

what happens if you remove mammillary bodies?

A

dense amnesia

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14
Q

what is transient global amnesia?

A

anterograde amnesia from some precipitating event, unknown cause

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15
Q

3 kinds of transient memory disorders?

A
  1. transient global
  2. transient epileptic
  3. post-traumatic
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16
Q

what’t eh most common dementia?

A

Alzheimer’s ~50%

17
Q

what is first signs of Alzheimers

A

mild cognitive impairment

18
Q

mild cognitive impairment is what 4 things?

A
  1. self reported complaint, hx 6-12mo
  2. objective memory impairement
  3. general cog is good
  4. normal ADLs
19
Q

Alzheimers Braak and Braak stag V-VI affects?

A

neocortex

20
Q

Alzheimers Braak and Braak stage I-II affects?

A

transentorhinal

21
Q

Alzheimers Braak and Braak stage III-IV affects?

A

limbic system

22
Q

what are two early memory compalints in MCI?

A
  1. name-face association

2. object -place association

23
Q

dysnomia is?

A

fluent empty language

24
Q

alzheimer’s affects not just memory but?

A

language too