CNS Blood Flow

Question 1

CNS uses how much% of CO?

Answer 1

10-20%

Question 2

if arterial blood flow changes, how does it affect CNS?

Answer 2

autoregulation system keeps the brain adequately perfused

Question 3

How is perfusion maintained in brain?

Answer 3

via dense network of vessels

Question 4

circle of Willis is formed by what two systems?

Answer 4

Internal Carotid

vertebro-basilar system

Question 5

vertebral artery comes off? goes through where?

Answer 5

off subclavian, through first 6 transverse foramina>foramen magnum

Question 6

ACA supplies what?

Answer 6

medial part of frontal and parietal lobes

Question 7

ACA supplies what functional territories?

Answer 7

motor and sensory for lower limb

Question 8

MCA supplies what?

Answer 8

lateral surface of brain and part of all 5 lobes

Question 9

MCA functional territories supply?

Answer 9

1. motor sensory for most body except UL

2. Language (Broca’s Wernicke)

Question 10

PCA supplies what?

Answer 10

medial and inferior temporal/occipital lobes

Question 11

PCA territories?

Answer 11

visual cortex

Question 12

What supplies basal ganglia and internal capsule?

Answer 12

lenticulostriate arteries

Question 13

what supplies pons?

Answer 13

pontine branches of basilar artery

Question 14

What supplies hypothalamus/thalamus?

Answer 14

posterio perforating branches off of PCA

Question 15

perforating vessels off the ACOM supply?

Answer 15

optic chiasm/hypothalamus

Question 16

2 named arteries that come off internal carotid before turning into MCA?

Answer 16

1. opthalmic artery

2. anterior choroidal:deep lateral structures, ventricles, hippocampus

Question 17

Lenticulostriate arteries supply?

Answer 17

Basal Ganglia

Internal capsule

Question 18

3 vessels that supply the cerebellum?

Answer 18

1. superior cerebellar artery
2. anterior inferior cerebellar artery (first branch of basilar)
3. posterior inferior cerebellar artery (branch of vertebral

Question 19

Midbrain supplied by?

Answer 19

superior cerebellar artery

Question 20

pons supplied by?

Answer 20

basilar artery

Question 21

medulla supplied by?

Answer 21

1. PICA (lateral)
2. Vertebral artery (ventro-lateral)
3. anterior spinal (medial)

Question 22

what is medial medullary syndrome?

Answer 22

damage to anterior spinal artery resulting in

1. hypoglossal n. damage
2. medial lemniscus damage
3. contralateral hemiparesis/hemideficit

Question 23

Spinal arteries are reinforced by?

Answer 23

1. radicular arteries

2. segmental branches of aorta (intercostal/lumbar)

Question 24

venous drainage of brain?

Answer 24

inferior sagittal>Galen&internal cerebral>straight sinus>superior sagittal>confluence>transverse sinus>sigmoid sinus>internal jugular

Question 25

what can diffuse across BBB?

Answer 25

gases, lipid soluble substances

Question 26

what is actively transported across BBB?

Answer 26

glucose, AAs