Medical Issues Vocab #2 Flashcards
pharmacodynamics
the actions of a drug on the body
pharmacodynamics components
mechanisms of action drug interactions side effects adverse reactions allergic reactions
pharmacotherapeutics
the study of the therapeutic uses and effects of drugs
pharmacokinetics
how the body acts on a drug
pharmacokinetics components
absorption
distribution
metabolism
elimination
absorption
process of getting the drug into the body through a variety of routes
absorption routes
oral rectal vaginal intravenous intramuscular inhalation topical
distribution
the process of delivering the drug throughout the tissues and fluids of the body
factors that effect distribution
whether the drug is fat or water soluble
the drug’s ability to cross the blood-brain barrier
hydrophilicity
water solubility
lipophilicity
fat solubility
metabolism
process by which a drug is changed into one or more chemical entities that differ from the parent drug
metabolism primary location
liver
elimination
process of getting a drug out of the body
includes the elimination of the drug and its metabolites
elimination methods
renal excretion
fecal excretion
half-life
the length of time that it takes for blood levels or tissue levels of a drug to decrease by one half;
half-life is ___ ___ to the volume of distribution and ____ ____ to the clearance
directly proportional
inversely proportional
enteral administration
orally admitted
parenteral ddministration
not orally admitted
iontophoresis
the administration of a drug into the body via electricity
phonophoresis
the administration of a drug into the body via ultrasound
agonist drugs
drugs that attach to cellular receptors in the body, causing stimulation of the receptor
antagonist drugs
drugs that attach to cellular receptors in the body, causing inhibition of the receptor
corticosteroids
a steroid hormone produced by the adrenal cortex that is used to treat inflammatory and allergic diseases
corticosteroids divisions
glucocorticosteroids (carb. metabolism)
mineralocorticosteroids (regulate electrolyte imbalance)
prothrombin time
test used to time clot formation
prothrombin time uses
can detect defects in the ability of the blood to coagulate, which are usually caused by a deficiency of factor V, VII, or X
narcotic analgesics
pain-relieving agents that stimulate the opiate receptors