Lymphatic and Immunity Flashcards

1
Q

Lymphatic system functions

A

return fluid/solutes
lipids absorbed by SI transported blood
Pathogens transported to lymph nodes

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2
Q

Vessels of lymphatic system parallel the vessels of the

A

circulatory system

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3
Q

Peristalsis

A

slow contracting of smooth muscle

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4
Q

extracellular matrix

A

outside the cell

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5
Q

extracellular fluid

A

not manufactured by cell

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6
Q

interstitial fluid

A

between cells

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7
Q

how many liters of lymph enter hear

A

3 liters

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8
Q

lymph nodes

A

lymph must pass through at least one node

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9
Q

thymus

A

originate in red bone marrow and site of t cells

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10
Q

spleen

A

recycling of RBCs

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11
Q

immunity

A

is the capacity to resist and combat infection by pathogens such as viruses, bacteria, fungi, protists and worms

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12
Q

Antigen

A

any molecule particle or cell recognized by the body as “non self”

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13
Q

PAMPs

A

pathogen associated molecular patterns

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14
Q

innate immunity

A

a general defense against infection; Immediate responses;

born with

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15
Q

adaptive immunity

A

is a sytem defenses specifically targets different antigens an individual may encounter during its lifetime;
acquired.

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16
Q

3 lines of defense are

A

physical, chemical and mechanical barriers; Skin for example
Innate
Adaptive

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17
Q

Phagocytes (WBC) are

A

cell eating

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18
Q

Secretory cells

A

mast cells

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19
Q

lymphocytes

A

B and T cells, NK cells

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20
Q

All white blood cells synthesize and secrete cell to cell signaling molecules

A

cytokines; which run the system that coordinate all aspects of immunity

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21
Q

Lysozyme

A

anti-bacterial enzyme

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22
Q

Innate immune system: complment proteins

A

are inactive in the blood &/Or interstitial fluid; become activated when they encounter antigen

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23
Q

Neutrophils are known as

A

kamikaze cells because they are short lived and explode to pathogens

24
Q

Monocytes

A

circulate in blood; precursors of Macrophages when they leave blood

25
Q

Macrophages

A

“Big eaters” in interstitial fluid engulf and digest essentially everything except undamaged cells

26
Q

Dendritic cells

A

Patrol tissues tha contact the external environment and also engulf pathogens

27
Q

Inflammation

A

response to tissue damage; characterized by redness, warmth and swelling/pain.

28
Q

Cytokines stimulate brain cells to

A

release chemicals which act on the hypothalamus- causing vasoconstriction, increased heart&respiratory rates.

29
Q

B cells synthesize, secrete and display

A

antibody Naiive B cells.

30
Q

MHC markers

A

human self proteins , indicator saying its infected

31
Q

Antibodies are Y shaped antigen receptors made by

A

B cells

32
Q

Cell mediated Immunity

A

Cytotoxic T cells and NK cells detect and destroy infected or altered body cells; cancerous cells

33
Q

Humoral Immunity

A

B cells produce antibodies that bind to antigens in blood or interstitial fluids

34
Q

Macrophage are in

A

fluids

35
Q

Dendricites are in

A

tissue

36
Q

Memory cells

A

Lymphocytes produce B&T cells which can produce memory cells that provide “memory” for immune system for next infection if occurs

37
Q

Effector cells

A

destroy most antigens-bearing agents

38
Q

Naive B or T cell has not yet

A

encountered its specific antigen

39
Q

Helper T cells bind antigen-MHC complexes on activated B cells and secrete

A

cytokines

40
Q

B cells display

A

antibodies on the cell membrane

41
Q

B cells also synthesize and secrete

A

Antibodies into blood

42
Q

cytoxic T cell release protein-digesting enzymes and

A

perforins

43
Q

Autoimmune system

A

an immune response that is misdirected against the person’s own tissues; ex: rheumatoid arthritis

44
Q

Primary immodeficiency

A

results of mutation; ex: boy in bubble

45
Q

Secondary immunodeficiency

A

results from a virus; ex: HIV

46
Q

New stem cells arise from

A

Red bone Marrow

47
Q

Old and destroyed/recycled are down by the

A

spleen

48
Q

Totipotent stem cell

A

pontential to make a human

49
Q

Unipotent stem cell

A

pontential to make anything

50
Q

b cells

A

extracellular; makes plasma cells and release anti bodies

51
Q

T cell

A

intracellular and cell mediated

52
Q

NK cells

A

natural cells, kill ‘altered’ cells. Intracellular. MHC is there or not

53
Q

Cytotoxic T cells

A

Kill with perforin; MHC must be present

54
Q

Neutrophils

A

first responder, phagocytes

55
Q

Dendritic cells

A

phagocytes, B cell, innate and acquired

56
Q

Eosinphills

A

worms

57
Q

basophils and mast cells

A

part of allergies; like histamine.