Lung cancer - non surgical options Flashcards
what percent of lung cancer are non small lung cell cancer
85%
what percent of lung cancers are small cell lung cancre
15%
what happends during a mdt meeting
discuses teh stading of teh cancer, the type and the patient whihx, and the possible therapeutic options
what its the easter cooperative group perfousce measuremt
give a number on their breathlessness e.g. 3 = has to rest for more than 50% of the day and 4 equals bed bound
what is the rough doubling time for a non small cell lung cancer
130 days
what si teh 5 year survical using surgery
about 40%
what requirements are needed for surgury
fev1 and lymph node sampling
what ar teh post oppoerative threray after surgy
rt, chemo
what stages are chemotherpy and radiothepry normally used
1 and 2
what is neoadjuvant therapy
given before procedures
what stadge lung cancer benifited from neoaddjvant cehmotherapy
3 only
what radiotheearpy ragimes are availible
monday to friady for 4 weeks, or 3 times a day for 12 consecutive days
what is teh 5 year survical for radiotherapy
about 20%
what test is essental for radiotherapy
peak flow
what is a risk on concurent chemotheray with rt
increse toxicity effects
what is the 2 year survical rate for ougbe cheoheary
27%
what is immunotherapy
giving the body chemical to incrae imune system response, this mean that it is more likely to attack the cancer cells
what is stereotactic ablative radiotherapy
very high doese of radiothery which can have similar outcomes to surgery
what are the pallitive care options
chemotherapy, immunotherapy, tki, palliative radiotherapy,
what is pdl1
a programmed death liganed that prevents the immune system attacking cells in the body, this is secreted by cancers
what is nivolumab
it stops being of pd1 and pdl1 and stops cancers being masked and not being destroyed by immune cells
what is the benifit of pallative radiotherpay
prevents bone metaais, cord compressoi, haemoptysis
what is the benifit of high dose pallative
helps if the diseas is to large to encoupass raiclly, has a survacla advantage
what is the doubling time for small lung cancer
29 days
what do small lung cancer look like histolically
limeitd to one hemithroax,
what is the treatment for small cell lung cancer in chemothepary
cisplaint and etoposide
what is the mediam survial for smallcell lung cancer in locailsed without reatment
8 months
what are the side effects of chemotherapy
marrow suppersion, (neutropanenic sepsis ), nausea, comiting, gi upset, mucositis, fatique, lethargy, neuropaty, incrased risk mi/ stroke, renal impairment
what are the side effects of radiotherapy
lethargy, risk to surrounding organs, pneumonits, dysphagia, fibrous, stricutre, increased risk mi
what is the side effects of immutotherapy
colitis(inflamtion of endo of gi), pneumonitis, dermatitis, endocrinopathies(endocrine disorders)
what is teh type of sepsis in chemotherapy
neutropaneic sepsis
what are tkis sutible for
those who can’t have chemotherapy
