Local anaesthetic blocks Flashcards
What are the 2 types of local anaesthetics and how are they metabolised?
Amides: Metabolized by liver (e.g. lidocaine, bupivacaine)
Esters: Metabolized by plasma cholinesterases (e.g. procaine)
How do local anaesthetics work?
Local anesthetics are weak bases that exist in equilibrium between:
- Non-ionized (neutral), lipid-soluble form (B): Penetrates lipid membrane
- Ionized (charged), water-soluble form (BH+): Binds to sodium channel receptor within channel pore, blocking nerve signal transmission
Why are local anesthetics formulated as acidic hydrochloride salts?
To increase water solubility & ionization (pH 4–7), ensuring effectiveness in their water-soluble, charged form
What is the purpose of adding vasoconstrictors (e.g., adrenaline) to local anesthetics?
To prolong duration of action by reducing systemic absorption
What is the purpose of a testicular block during castration?
Provides intraoperative nociception & postoperative pain relief by diffusing to spermatic cord & associated structures
Reduces pain from surgical crushing of tissue at castration site
How is a testicular block performed?
- Use sterile hypodermic needle (25- to 22-Ga, length depending on patient size)
- Insert needle into testicular body, directing tip toward spermatic cord
- Aspirate to ensure needle is not in blood vessel
- Inject recommended dose of local anesthetic (bupivacaine, ropivacaine, or lidocaine) until testicle becomes slightly turgid or volume limit is reached
How do we inject local anaesthetic for a testicular block for castration?
Cats: Inject local anesthetic as needle exits testicle to block skin & subcutaneous tissue over incision
Dogs: Inject anesthetic into skin & subcutaneous tissue at prescrotal incision site
How is local anaesthetic used during an ovariohysterectomy?
Direct infiltration of mesovarium ligament
Alternatively, splash block can be applied to the ovaries
Additional step:
- lavage of peritoneal cavity with local anaesthetic to provide additional analgesia (careful with dosage)
skin & subcutaneous tissues at incision site should also be infiltrated with local anaesthetic.
What is retrobulbar anaesthesia, and when is it used?
Retrobulbar anaesthesia involves injecting local anaesthetic behind eye to block nerves & provide pain relief during ophthalmic procedures, such as enucleation
What are the indications for lumbosacral and sacrococcygeal epidurals in veterinary medicine?
Tail amputations (canine and feline).
Perineal urethrostomies.
Anal sacculectomies.
Catheterisation for relief of urethral obstruction.
Perineal relaxation for the delivery of puppies/kittens.
Other surgeries involving the penis or perineal region.
What anatomical regions are targeted with lumbosacral and sacrococcygeal epidurals?
Lumbosacral epidural: Provides analgesia & anaesthesia for hindlimb and pelvic region surgeries
Sacrococcygeal epidural: Focused on the tail and perineal region
What is the purpose of a rostral maxillary (infraorbital) dental block?
It provides analgesia for rostral maxillary soft tissues only (not teeth or bone)
Where is the local anaesthetic injected for a rostral maxillary (infraorbital) block?
injection made near infraorbital foramen, targeting infraorbital nerve
What nerve block is this?
Rostral maxillary (infraorbital)