Lipid Modifications and Membrane Localization

Question 1

What type of lipid modification is this? What are the parameters?
What side is this done on?

Answer 1

Enzymes add the bolded molecules to the amino acid(s) listed.
These lipid modifications make the protein able to anchor to the hydrophobic membrane core. Making them act more like integral membrane proteins.

Question 2

What type of lipid modification is this? What are the parameters?
What side is this done on?

Answer 2

Enzymes add the bolded molecules to the amino acid(s) listed.
These lipid modifications make the protein able to anchor to the hydrophobic membrane core. Making them act more like integral membrane proteins.

Question 3

What type of lipid modification is this? What are the parameters?
What side is this done on?

Answer 3

Enzymes add the bolded molecules to the amino acid(s) listed.
These lipid modifications make the protein able to anchor to the hydrophobic membrane core. Making them act more like integral membrane proteins.

Question 4

We have learned 3 broad classes of anchored proteins.
GPI
Palmitoyl
And Prenylated
Which side and where on the membrane protien are they found?

Answer 4

Question 5

Define what Caveolin is.

Answer 5

Shape the membrane protein from inside the cell!
Red in figure shows palmitoylation of Caveolin.

Question 6

The Red blood cell (RBC) is specialized. Explain how it’s special.

Answer 6

Question 7

What shape do red blood cells have?
Why does it have the shape and what important qualities does the red blood still have because of it?

Answer 7