Hemocyanins and Sickle Cell Anemia Flashcards
1
Q
What are Hemocyanins? What is its function? What are the two types of hemocyanins?
A
2
Q
What type of symmetry do Hemocyanins have?
A
3
Q
Describe the structure of the oxygen binding center for Hemocyanins.
A
Copper does get oxidized, unlike iron in hemoglobin!
4
Q
What is sickle cell anemia?
A
A genetic disease that involves the mutation of hemoglobin. Radically altered morphology of red blood cells.
HbS= mutation that causes disease.
HbA= normal hemoglobin.
5
Q
What molecularly happens to cause sickle cell anemia?
A
6
Q
What makes the HbS mutation so bad? (Why is the B1-B2 interaction so disastrous?)
A
7
Q
Why is HbS so common? Hint: it’s especially common in Africa.
A
SPECIFICALLY HETEROZYGOTES GET THE MOST BENEFIT.
